Interesting: Weekly Highlights From the JAMA Network

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Oct 26, 2025, 10:15:23 AM (16 hours ago) Oct 26
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These featured articles published during the past week have been selected by our editors. Click below to read them on the JAMA Network website for free.

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October 26, 2025
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These articles were most popular among readers in the last week. Click below to read them for free.

JAMA
Clinical Review & Education
AI, Health, and Health Care Today and Tomorrow: The JAMA Summit Report on Artificial Intelligence
Derek C. Angus, MD, MPH; Rohan Khera, MD, MS; Tracy Lieu, MD, MPH; et al
News & Insight
Microplastics and Human Health
Shruthi Mahalingiah, MD; Kari C. Nadeau, MD, PhD; David C. Christiani, MD, MPH
Research
Social Media Use Trajectories and Cognitive Performance in Adolescents
Jason M. Nagata, MD, MSc; Jennifer H. Wong, MPH; Kristen E. Kim, BA; et al
JAMA Cardiology
Research
Clonal Hematopoiesis and Cardiovascular Disease and Bleeding Risk and the Effectiveness of Aspirin
Zoe K. McQuilten, MBBS, PhD; Le T. P. Thao, PhD; Alexander G. Bick, MD, PhD; et al
Research
Short-Term Exposure to Low and High Temperatures and Mortality Among Patients With Heart Failure in Sweden
Wenli Ni, PhD; Lina Benson, MSc; Petter Ljungman, MD, PhD; et al
Research
Prognostic Value of Papillary Muscle Scarring in Patients With Dilated Cardiomyopathy
Yodying Kaolawanich, MD; David C. Wendell, PhD; Han W. Kim, MD; et al
JAMA Dermatology
News & Insight
Chronic Spontaneous Urticaria
Gil Yosipovitch, MD; Andrea D. Maderal, MD; Scott A. Elman, MD
Clinical Review & Education
Unusual Congenital Scalp Lesion in a Child
Marina de la Puente Alonso, MD; Verónica Parra Blanco, MD; Minia Campos Domínguez, MD, PhD
Clinical Review & Education
Dowling-Degos Disease
Moizza Tahir, MBBS, MHPE; Asma Malik, MBBS; Saima Shahid, MBBS
JAMA Health Forum
Opinion
Most-Favored-Nation Drug Pricing—How Courts Could Shape Future Health Regulation
Nicholas Bagley, JD; Craig Garthwaite, PhD; Benedic Ippolito, PhD
Research
Glucagon-Like Peptide-1 Receptor Agonist Order Fills and Out-of-Pocket Costs by Race, Ethnicity, and Indication
Ameet Sarpatwari, PhD, JD; Mark J. Soto, MA; Ishani Ganguli, MD, MPH; et al
Opinion
E-Cigarettes in Historical Context—Innovation, Risk, and Regulation
Michael F. Pesko, PhD; Jamie Hartmann-Boyce, PhD; Rachel Y. L. Fung, PhD; et al
JAMA Internal Medicine
Research
Effectiveness of Colchicine for the Treatment of Long COVID: A Randomized Clinical Trial
Abhinav Bassi, MPH; Niveditha Devasenapathy, PhD, MBBS, MSc; Shani S. Thankachen, MPH; et al
Research
Food Insecurity Interventions to Improve Blood Pressure: The Healthy Food First Factorial Randomized Clinical Trial
Seth A. Berkowitz, MD, MPH; Alice S. Ammerman, DrPH, MPH; Patricia Knoepp, MPH; et al
Research
Slow-Tempo Music and Delirium/Coma-Free Days Among Older Adults Undergoing Mechanical Ventilation: A Randomized Clinical Trial
Babar A. Khan, MD, MS; Sikandar H. Khan, DO, MS; Anthony J. Perkins, MS; et al
JAMA Network Open
Research
Implications of a New Obesity Definition Among the All of Us Cohort
Lindsay T. Fourman, MD; Aya Awwad, MD, MMSc; Alba Gutiérrez-Sacristán, PhD; et al
Research
Screen Time and Standardized Academic Achievement Tests in Elementary School
Xuedi Li, MSc; Charles D. Keown-Stoneman, PhD; Jessica A. Omand, PhD; et al
Research
First-Trimester mRNA COVID-19 Vaccination and Risk of Major Congenital Anomalies
Clément Bernard, MSc; Tom Duchemin, PhD; Lise Marty, PhD; et al
JAMA Neurology
Research
Sedation vs General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke: The SEGA Randomized Clinical Trial
Peng Roc Chen, MD; Carlos A. Artime, MD; Sunil A. Sheth, MD; et al
Clinical Review & Education
Diffuse Reversible Leukoencephalopathy in Intracranial Aspergillus Infection
Haijiang Li, MB; Haimei Sun, MD; Yanbing Hang, MD
JAMA Oncology
Research
Artificial Intelligence–Detected Tumor-Infiltrating Lymphocytes and Outcomes in Anti–PD-1–Based Treated Melanoma
Mark Schuiveling, MD; Isabella A. J. van Duin, PhD; Laurens S. ter Maat, PhD; et al
Clinical Review & Education
Guidelines for Next-Generation Sequencing in Sarcoma Diagnosis and Treatment: A Consensus Review
César Serrano, MD, PhD; Sebastian Bauer, MD; Jean-Yves Blay, MD, PhD; et al
JAMA Ophthalmology
Research
Pickleball-Related Ocular Injuries Among Patients Presenting to Emergency Departments
Corey R. Lacher, MD; Irene Koc, MD; Jonathan C. Tsui, MD
Research
Endothelial Cell Loss 1 Year After Successful DMEK in the Diabetes Endothelial Keratoplasty Study: A Randomized Clinical Trial
Jonathan H. Lass, MD; Beth Ann Benetz, MA; David D. Verdier, MD; et al
Research
Leveraging Large Language Models to Generate Multiple-Choice Questions for Ophthalmology Education
Shahrzad Gholami, MSC, PhD; Daniel B. Mummert, MFA; Beth Wilson, MBA, CHCP; et al
JAMA Otolaryngology - Head & Neck Surgery
Clinical Review & Education
Midline Tongue Defect in a Pediatric Patient
Katherine C. Babin, MD; Kaylee Zettler, BS; Jeffrey Carron, MD
Opinion
Contralateral Tonsil in p16-Positive Tonsil Squamous Cell Carcinoma
Louis-Xavier Barrette, MD; Michelle Gentile, MD, PhD; Karthik Rajasekaran, MD
Research
Reimbursement for Thyroid Surgery and Potential Solutions
Philip R. Brauer, MD; David Octeau, MD; Benjamin Wajsberg, MD; et al
JAMA Pediatrics
Opinion
A Collaborative Approach to Assessment and (Non)Diagnosis of Autism
Lester Liao, MD, MTS; Mohammad Zubairi, MD, MEd
Research
Cannabis and Alcohol Use to Initiate Sleep Among Young Adults
Megan E. Patrick, PhD; Yuk C. Pang, PhD; Yvonne M. Terry-McElrath, MSA
Research
Derivation and Validation of Predictive Models for Early Pediatric Sepsis
Elizabeth R. Alpern, MD, MSCE; Halden F. Scott, MD, MSCS; Fran Balamuth, MD, PhD, MSCE; et al
JAMA Psychiatry
Research
Serial Ketamine Infusions as Adjunctive Therapy to Inpatient Care for Depression: The KARMA-Dep 2 Randomized Clinical Trial
Ana Jelovac, PhD; Cathal McCaffrey, MB, BCh, BAO; Masashi Terao, MD; et al
Research
Pragmatic Comparative Effectiveness of Primary Care Treatments for Posttraumatic Stress Disorder: A Randomized Clinical Trial
John C. Fortney, PhD; Debra L. Kaysen, PhD; Charles C. Engel, MD; et al
Research
Contrasting Risk Profiles for Suicide Attempt and Suicide Using Danish Registers and Genetic Data
Fenfen Ge, MD, PhD; Yue Wang, MD, PhD; Esben Agerbo, PhD; et al
JAMA Surgery
Clinical Review & Education
The Difficult Cholecystectomy
Vincenzo Villani, MD; Lilian S. Kao, MD, MS; Yuman Fong, MD, DSc
Research
Mesh Weight in Reoperation for Recurrence After Laparoscopic Inguinal Hernia Repair
Can Deniz Deveci, MD; Jason Joe Baker, PhD; Jacob Rosenberg, DMSc
Research
Gene Expression Profile–Based Test to Predict Melanoma Sentinel Node Status: The MERLIN_001 Study
Tina J. Hieken, MD; Michael E. Egger, MD, MPH; Christina V. Angeles, MD; et al

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