The New England Journal of Medicine, June 12, 2025

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Jun 12, 2025, 12:12:02 AM6/12/25
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This Week at NEJM.org, June 12, 2025

CLINICAL DECISIONS

Setting for Initial Diabetes Education

Featured Image

A. Cheung, J.B.Q. Quintos, and S. Agarwal | N Engl J Med 2025;392:2164-2167

This feature about a teenager with a new diagnosis of type 1 diabetes mellitus offers a case vignette accompanied by two essays, one supporting referral of the patient to a hospital for inpatient diabetes education and the other recommending intensive outpatient diabetes education.

Read the opinions and cast your vote at NEJM.org.

Poll
Perspective

Undermining Women’s Health Research — Gambling with the Public’s Health

A.N. Kallen and Others

N Engl J Med 2025;392:2185-2187 | Published Online May 28, 2025

Audio

Addressing Antifungal Drug Resistance — A “One Health–One World” Challenge

G.R. Thompson III and A.N. Desai

N Engl J Med 2025;392:2187-2189 | Published Online June 7, 2025

Acknowledging Racism, Building Trust — Conversations That Matter in Maternal Medicine

B.F. Kahn

N Engl J Med 2025;392:2189-2191 | Published Online June 7, 2025

Original Articles

Nerandomilast in Patients with Idiopathic Pulmonary Fibrosis

L. Richeldi and Others

N Engl J Med 2025;392:2193-2202 | Published Online May 18, 2025

CME Video

Nerandomilast in Patients with Progressive Pulmonary Fibrosis

T.M. Maher and Others

N Engl J Med 2025;392:2203-2214 | Published Online May 19, 2025

Video

Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight

L. Ji and Others

N Engl J Med 2025;392:2215-2225 | Published Online May 25, 2025

CME Video

Sustained Clinical Benefit of AAV Gene Therapy in Severe Hemophilia B

U.M. Reiss and Others

N Engl J Med 2025;392:2226-2234

Brief Report: Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

K. Musunuru and Others

N Engl J Med 2025;392:2235-2243 | Published Online May 15, 2025

Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes

R. Agarwal and Others

DOI: 10.1056/NEJMoa2410659 | June 5, 2025

Review Article

Nutrition in Medicine: Malnutrition in Older Adults

A.J. Cruz-Jentoft and D. Volkert

N Engl J Med 2025;392:2244-2255

CME

Image Challenge

More Image Challenge
Image Challenge

What’s the diagnosis?

Answer

Additional Published Content

Additional Published Content
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Images in Clinical Medicine

Cardiac Injury Detected by Smartwatch

T.R. Basala and S.W. Sharkey

N Engl J Med 2025;392:2256 | Published Online June 7, 2025

Ramsay Hunt Syndrome

J. Guo and W. Li

N Engl J Med 2025;392:e53

Case Records of the Massachusetts General Hospital

Case 16-2025: A 34-Year-Old Man with a Nasopharyngeal Mass

R.W. Bergmark and Others

N Engl J Med 2025;392:2257-2265

CME
Editorials

Progress through Persistence — Turning the Page in Pulmonary Fibrosis Clinical Trials

J.S. Lee

N Engl J Med 2025;392:2267-2269 | Published Online May 19, 2025

Overweight and Obesity — Capturing the Whole Picture

V.R. Aroda and L. Perreault

N Engl J Med 2025;392:2269-2271 | Published Online May 25, 2025

Progress in the Development of N-of-1 Therapy

P. Marks

N Engl J Med 2025;392:2271-2272 | Published Online May 15, 2025

Science behind the Study: Personalized Gene Editing to Treat an Inborn Error of Metabolism

A.L. Gropman and A.C. Komor

N Engl J Med 2025;392:2273-2276 | Published Online May 15, 2025

Medicine and Society

John Collins Warren — Journal Founder, Institution Builder, and Racial Theorist

C.D.E. Willoughby and Others

N Engl J Med 2025;392:2277-2281

Correspondence

BCMA-Targeted T-Cell Engager for Autoimmune Hemolytic Anemia after CD19 CAR T-Cell Therapy

Long-Term Effects of Empagliflozin in Chronic Kidney Disease

Blinatumomab in Childhood B-Cell Acute Lymphoblastic Leukemia

Case 4-2025: A Man with Syncope, Ankle Swelling, and Abnormal Chest Imaging

NEJM CareerCenter
Physician Jobs June 12, 2025
Chiefs/Directors/Dept. Heads California
Electrophysiology Chief opportunity in Los Angeles
The Department of Cardiology, Smidt Heart Institute has an exciting opportunity for a senior faculty leader to serve as Division Director, Cardiac Electrophysiology. This is an exceptional opportunity to lead and grow a thriving electrophysiology....
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Cardiologist needed to join growing team in Fort Worth
The Medical City Institute for Advanced Cardiac Care is seeking a board-certified advanced heart failure and transplant cardiologist to join our growing team. This position offers the opportunity to work in one of the largest healthcare systems in....
Looking for a new practice opportunity? View these jobs and other listings at NEJM CareerCenter.

Search now for both permanent and locum tenens jobs in many specialties.

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--
Prashanth N Suravajhala, Ph.D.
Professor, Systems Genomics Lab,
Department of Biosciences, Room # 323D, AB-3, 
Manipal University Jaipur, Dehmi Kalan 303007,  India.
Founder, Bioclues.org
Twitter: @prashbio

"One rule is important in science- only courageous people win "   ~ Max Planck
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