Bioclues Newsletter January-March 2022

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Quarterly newsletter of Bioclues.org
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January - March 2022 | Vol 13 | Issue 1
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BIOCLUES SPEAKS
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Dear Members,

Bioclues is a non-profit virtual organization for, by, and of the Indian Bioinformaticians. One of the fastest growing bioinformatics societies in India, Bioclues was built on the foundation of connecting people. Bioclues aims to bring together the Indian bioinformaticians, foster a strong working mentor-mentee relationship, provide access to bioinformatics resources, organize conferences and workshops besides imparting information about research, training, education, employment, and current events and news from bioinformatics, genomics, and related fields.

Read on to know more about our latest events and members

Stay Safe | Be healthy
Editors: Team Bioclues

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Happy International Women's Day: March 8th, 2022
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“Imagine a gender equal world.
A world free of bias, stereotypes, and discrimination.
A world that is diverse, equitable, and inclusive.
A world where difference is valued and celebrated.
Together we can forge women's equality”

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We have celebrated International Women’s Day 2022 on 8th March 2022. Today, we cannot imagine science without women and their outstanding contributions, overcoming gender bias remains an issue in our society.  

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WE-CARE Introduction
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Towards the end of 2021, Bioclues had taken the initiative to develop Women Empowerment for career break women and encourage them to continue re-establish themselves in the science work front. On the eve of International Women’s Day, 8th March, 2022, we had eminent and reputed speakers from all over the country - Dr. Chandana Basu, Dr. Krishna Goyal and Ms. Anand Saxena, who inspired the upcoming young generation with their success story, with a special note on establishment of start-ups! A wonderful panel discussion! Speakers as well as participants had fascinating sessions in sharing their experiences and thoughts on upholding societal views on women's education. This was really such phenomenal session we experienced, We-CARE, as part of Bioclues, has developed a bridging network for women scientists, who had break in their career, in further re-establishing scientific identity of women and to portray that women scientists have been and will always be capable to establish multi-potent skills in and across their homestead! The wide-across celebration of International Women's Day was a whole-hearted effort contributed by WE-CARE!!

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LEADER IN SPOTLIGHT
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Dr. Bhawana Bissa

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Assistant Professor
Department of Biochemistry
Central University of Rajasthan
Rajasthan, India

 

 

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My journey as a scientist began when I enrolled for my PhD at All India Institute of Medical Sciences, Delhi. Being good at academics, my career options always involved being either a doctor or a scientist. As fate would have it, I succeeded in getting my fellowship and starting my PhD at AIIMS under guidance of Prof. Kunzang Chosdol.

 

The first taste of what scientific ecstasy might feel like, came when I could successfully knock down a gene in a glioblastoma cell line. The research work eventually proved the oncogenic role of FAT1 gene in glial tumorigenesis and was published in the journal Oncogene. The sheer pleasure of seeing the cells and the processes within them gave me unprecedented happiness. As with most PhD scholars, I would spend hours in the lab, just for getting that one ‘experiment’ done right. My enthusiasm to continue in science could not be tapered down by essential life events. Marriage and the birth of my son were a part of my PhD journey.

 

After my PhD, I joined IGIB, Delhi for my first post doc and worked with Dr. Soumya Sinha Roy to understand the role of autophagy in cancer chemoresistance. Later in 2015, with motivation from family, I did postdoctoral training at Ohio State University, where my research involved elucidating the role of lysosomal nucleoside transporters in regulating the autophagy pathway. Soon after I started working on autophagy, I was thrilled when the Nobel prize was awarded in 2016 for discovery of this pathway. Ultimately, I started my second post doctoral training with a renowned scientist in the field of autophagy, Prof. Vojo Deretic at University of New Mexico. Here, I was engaged in deciphering the activation of AMPK (Adenosine monophosphate kinase) by lysosomal damage. During my tenure at University of New Mexico, I enjoyed working with American, European and Chinese colleagues, which enhanced my
perspectives about research and life in general. My research work identified a novel pathway involved in AMPK activation after lysosomal damage and the study got published in Molecular Cell. My post-doctoral training imparted immense confidence and passion to start my own lab as Independent Principal Investigator. 

 

In 2019, I joined Central University of Rajasthan as Assistant Professor in Dept. of Biochemistry. Initially, the daunting task of setting up my own laboratory made me apprehensive of a career in science. But, gradually I learnt the art of juggling teaching, research and administrative work. With recommendation for research grants from UGC, SERB and ICMR, I was in a good position to begin my scientific exploration. The next haunting question was how to begin experimentation, whom to enroll for PhD guidance and how to approach for collaborations. But as it is said, “where there is will, there is a way”, I found people interested in similar areas of research as mine. Slowly and steadily my lab is built and presently we are working to elucidate the role of autophagy in cancer progression, understanding transcriptional regulation of AMPK subunits, identifying the crosstalk between autophagy and exosome pathways and are open to new and interesting research directions. The research career trajectory and timelines are different for different people but as long as your love for science and your passion for finding the unknowns is alive, you are on the right track. 

 

My advice to young researchers is that do not run after popular science but rather look for areas of research which have been abandoned, areas which are marred by contradictions and areas which question the fundamental dogmas. Be fearless in traversing the uncharted waters for these are the areas that harbor the maximum potential for breakthroughs and discoveries. The path will undoubtedly be precarious but with constant zeal and enthusiasm the results will be fabulous.

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OUR PAST EVENTS
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In ‘Sci’versation with Prash:

Kiran K Telukunta, Ph.D.

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Founder, TMS Foundation
on January 07, 2022.

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View recording >>

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Insights into SARS-CoV2 antibody titer measures

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by Ram Jaiswal M.D., Director, Transplant Immunology, MGUMST, Jaipur on January 27, 2022.

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View recording >>

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How to write an effective cover letter | LanBix2022

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Dan Bosler, Ph.D., N.V. Chandrasekharan, Ph.D., Sakshi Singh, Ph.D., Anuj Kumar, Ph.D. on January 29, 2022.

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View recording >>

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GCCI Webinar: Sickle cell and Thalassemia: Why to screen ourselves?

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Naresh Tayade, M.Ch.,Director, Life Care Hospitals, Amaravan | February 10, 2022.

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View recording >>

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In ‘Sci’versation with Prash:

Ratnagiri Polavarapu, Ph.D.

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Director, Genomix Biotech, USA/India & Advisor, NIH on February 18, 2022.

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View recording >>

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In ‘Sci’versation with Prash:

Madhurima Kahali, Ph.D.

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Editor II, Life Sciences, CRC Press, Taylor and Francis on March 4, 2022.

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View recording >>

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GCCI Webinar: Challenges in the areas of genetic disorders and counselling

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by Annie Q Hassan, Ph.D., Senior Consultant, Kamineni Hospitals, Hyderabad on March 16, 2022.

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View recording >>

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In ‘Sci’versation with Prash:

Sunil K. Polipalli, Ph.D.

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Senior Scientist, MAMH, Lok Navak Hospital on March 18, 2022.

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RECENT PUBLICATIONS
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  1. Book chapter: Manjari, K.S., Chakraborty, D., Kumar, A. and Singh, S. (2021). Biodiversity and Importance of Plant Bioprospecting in Cosmetics. In Bioprospecting of Plant Biodiversity for Industrial Molecules (eds S.K. Upadhyay and S.P. Singh). https://doi.org/10.1002/9781119718017.ch10
     
  2. Editorial Perspective: Shukla N, Prasad A, Kanga U, Suravajhala R, Nigam VK, Kishor PK, Polavarapu R, Chaubey G, Singh KK, Suravajhala P. SARS-CoV-2 Transgressing LncRNAs Uncovers the Known Unknowns. Physiol Genomics. 2021 Sep 7. doi: 10.1152/physiolgenomics.00075.2021. Epub ahead of print. PMID: 34492207.
     
  3. Review: Choudhary C, Sharma S, Meghwanshi KK, Patel S, Mehta P, Shukla N, Do DN, Rajpurohit S, Suravajhala P, Shukla JN. Long Non-Coding RNAs in Insects. Animals (Basel). 2021 Apr 14;11(4):1118. doi: 10.3390/ani11041118. PMID: 33919662; PMCID: PMC8069800.
     
  4. Research: Suravajhala R, Parashar A, Choudhir G, Kumar A, Malik B, Nagaraj VA, Padmanaban G, Polavarapu R, Suravajhala P, Kishor PBK. Molecular docking and dynamics studies of curcumin with COVID-19 proteins. Netw Model Anal Health Inform Bioinform. 2021;10(1):44. doi: 10.1007/s13721-021-00312-8. Epub 2021 Jun 10. PMID: 34131556; PMCID: PMC8192041.
     
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Introducing IN-KIND Life Memberships
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Dear Members,

Bioclues as a non-profit organization would like to introduce 100 "in-kind" Life Members (LM) of our society and accorded from all States and Union Territories of India. In the next one month, we want to have 100 "in-kind" LMs who are needy, facing financial problems, but love doing bioinformatics, and are eager to join this society. If you have any student who is deprived of taking services at the expense of not being able to pay the membership fee, please let us know! The members would be given a full fee waiver for Life Membership. We anticipate that these less-privileged members will bring one paid LM each in due course.

Contact our secretary to express your interest sugu...@bioclues.org

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Check out the Benefits enjoyed by a Life Member!

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This Year (2021-22) In Kind members:
 

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  1. Madhurima Kahali
  2. Dr. Bipin Nair
  3. Anchita Prasad
  4. Lessa Fabrice Tchohou
  5. Prasad Manne
  6. Indrani Biswas
  7. Shalini Mukherjee
  8. Sandeep Chavan
  9. Bhumandeep Kaur
  10. Arya Aloor
  11. Vandana Sankar
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   12. Shyam Diwakar 
   13. Indhulekha Pillai
   14. Ajith M
   15. Sanjay Pal
   16. Geetha Kumar
   17. Sundarslal
   18. Jayashree S 
   19. Nidheesh M
   20. Rajaguru Aradhya
   21. Nandita Mishra
   22. Somesh Kumar

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LIFE MEMBERSHIP
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Become a Life Member!

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Benefits enjoyed by a Life Member

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BIXS PROGRAMME UPDATES
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Bioinformatics for School children (BIXS) is a flagship programme of Bioclues where school children aged 12-18 years are given an introduction to bioinformatics. The first three batches passed out successfully in December 2020, June 2021 and December 2021. The fourth batch kicks off from April, 2022 with an orientation. 
The call for the fourth cohort is open now!
If interested to enroll your ward, please fill the form here.


Brief curriculum weeks ( Two lectures a month during Saturdays) :
 

  1. Introduction to Bioinformatics
  2. Molecules
  3. Microbiology
  4. Big data
  5. Basics of Linux programming
  6. Systems biology and Protein Interactions
  7. Statistics
  8. Genetics
  9. 9-12 orientation followed by 16-24 weeks of projects

 

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STUDENT CORNER

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Bioclues have a well established Mentor-Mentee relationship, in which every student from both North and South chapters of Bioclues are given an opportunity to get trained in several skills. Leading scientists here possess wide research expertise right from Bioinformatics, system biology till deep learning methods or algorithms of artificial intelligence, molecular-cell biology or working in area of hard core biotechnology, which is published in and across reputed journals! Gaining experience in and across either of the subjects or expertise allows to develop nourishing skills for the students, to develop with revolutionary scientific ‘seed-soil’ platform!

 

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OUR INDUSTRY PARTNERS

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NanoTemper

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Enabling everyone to do science that matters by always pushing the limits

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WOULD YOU LIKE TO CONTRIBUTE?

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We would love to publish your research highlights, achievements, popular science articles, poems, drawing, cartoon or photographs. 

Write to us at sak...@bioclues.org.

Newsletter Editors: Team Bioclues

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BIOinformatics CLUb for Experimenting Scientists (BIOCLUES)
Mail: ad...@bioclues.org
 
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