The biophysical landscape of viral evolution // Proceedings of the National Academy of Sciences Vol. 121, No. 27, July 2, 2024 is now available online

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New Issue Available JULY 2, 2024  |  VOL.121  |  NO.27 VIEW TABLE OF CONTENTS

Special Feature Physics Meets Machine Learning Machine learning meets physics: A two-way street Herbert Levine and Yuhai Tu Machine learning in biological physics: From biomolecular prediction to design Jonathan Martin, Marcos Lequerica Mateos, José N. Onuchic, Ivan Coluzza and Faruck Morcos Learning dynamical systems from data: An introduction to physics-guided deep learning Rose Yu and Rui Wang Representations and generalization in artificial and brain neural networks Qianyi Li, Ben Sorscher and Haim Sompolinsky APACE: AlphaFold2 and advanced computing as a service for accelerated discovery in biophysics Hyun Park, Parth Patel, Roland Haas and E. A. Huerta Pairing interacting protein sequences using masked language modeling Umberto Lupo, Damiano Sgarbossa and Anne-Florence Bitbol Programming patchy particles for materials assembly design Ella M. King, Chrisy Xiyu Du, Qian-Ze Zhu, Samuel S. Schoenholz and Michael P. Brenner Sampling with flows, diffusion, and autoregressive neural networks from a spin-glass perspective Davide Ghio, Yatin Dandi, Florent Krzakala and Lenka Zdeborová Explaining neural scaling laws Yasaman Bahri, Ethan Dyer, Jared Kaplan, Jaehoon Lee and Utkarsh Sharma The neuron as a direct data-driven controller Jason J. Moore, Alexander Genkin, Magnus Tournoy, Joshua L. Pughe-Sanford, Rob R. de Ruyter van Steveninck and Dmitri B. Chklovskii

This Week in PNAS In This Issue

Retrospective Daniel Kahneman: The psychologist who won a Nobel Prize in Economics for replacing Homo economicus with flesh-and-blood humans Maya Bar-Hillel

Profile Profile of Jonathan C. Cohen Jennifer Viegas

Commentaries The biophysical landscape of viral evolution Claus O. Wilke Thermoelectricity, metallic liquidity, and magnetohydrodynamics Kamran Behnia Why we need long-term monitoring to understand ecosystem change Robert D. Hollister

Letters Reconstruct the intertropical convergence zone over the Indo-Pacific Warm Pool with extended records and empirical orthogonal function Fuzhi Lu, Francesco S. R. Pausata and