How Science intersects with culture AND more in PNAS

[Virtual Post Bioclues]

Proceedings of the National Academy of Sciences 17 January 2017; Vol. 114, No. 3 This Week in PNAS In This Issue Letters (Online Only) Relevance of Kondo physics for the temperature dependence of the bulk modulus in plutonium Marc Janoschek, Gerry Lander, Jon M. Lawrence, E. D. Bauer, Jason C. Lashley, Mark Lumsden, Douglas L. Abernathy, and J. D. Thompson Reply to Janoschek et al.: The excited δ-phase of plutonium Albert Migliori, Per Söderlind, Alexander Landa, Franz J. Freibert, Boris Maiorov, B. J. Ramshaw, and Jon B. Betts Science and Culture Science and Culture: Searching for shared inspiration, artists head to the world’s largest science experiment  Amber Dance How science intersects with culture. Core Concepts Core Concept: How nonequilibrium thermodynamics speaks to the mystery of life  Stephen Ornes A brief introduction to emerging topics in science. Commentaries Astrocytes fuel the fire of lymphocyte toxicity after stroke Meaghan Roy-O’Reilly and Louise D. McCullough When bottom-up meets top-down Zvi Shtein and Oded Shoseyov When protected areas prove insufficient: Cheetah and “protection-reliant” species Joshua R. Ginsberg PNAS Plus Significance Statements PNAS Plus Significance Statements Brief statements written by the authors about the significance of their papers. Perspective Opportunity for marine fisheries reform in China Ling Cao, Yong Chen, Shuanglin Dong, Arthur Hanson, Bo Huang, Duncan Leadbitter, David C. Little, Ellen K. Pikitch, Yongsong Qiu, Yvonne Sadovy de Mitcheson, Ussif Rashid Sumaila, Meryl Williams, Guifang Xue, Yimin Ye, Wenbo Zhang, Yingqi Zhou, Ping Zhuang, and Rosamond L. Naylor Physical Sciences Applied Physical Sciences Stochastic initiation and termination of calcium-mediated triggered activity in cardiac myocytes  Zhen Song, Zhilin Qu, and Alain Karma Programming function into mechanical forms by directed assembly of silk bulk materials  Benedetto Marelli, Nereus Patel, Thomas Duggan, Giovanni Perotto, Elijah Shirman, Chunmei Li, David L. Kaplan, and Fiorenzo G. Omenetto Matrix stiffening promotes a tumor vasculature phenotype  Francois Bordeleau, Brooke N. Mason, Emmanuel Macklin Lollis, Michael Mazzola, Matthew R. Zanotelli, Sahana Somasegar, Joseph P. Califano, Christine Montague, Danielle J. LaValley, John Huynh, Nuria Mencia-Trinchant, Yashira L. Negrón Abril, Duane C. Hassane, Lawrence J. Bonassar, Jonathan T. Butcher, Robert S. Weiss, and Cynthia A. Reinhart-King Biophysics and Computational Biology Cell morphology drives spatial patterning in microbial communities William P. J. Smith, Yohan Davit, James M. Osborne, Wook Kim, Kevin R. Foster, and Joe M. Pitt-Francis Chemistry Statistical mechanical model of gas adsorption in porous crystals with dynamic moieties  Cory M. Simon, Efrem Braun, Carlo Carraro, and Berend Smit Directional emission from dye-functionalized plasmonic DNA superlattice microcavities Daniel J. Park, Jessie C. Ku, Lin Sun, Clotilde M. Lethiec, Nathaniel P. Stern, George C. Schatz, and Chad A. Mirkin Computer Sciences On-demand high-capacity ride-sharing via dynamic trip-vehicle assignment  Javier Alonso-Mora, Samitha Samaranayake, Alex Wallar, Emilio Frazzoli, and Daniela Rus Engineering Imaging individual neurons in the retinal ganglion cell layer of the living eye   Ethan A. Rossi, Charles E. Granger, Robin Sharma, Qiang Yang, Kenichi Saito, Christina Schwarz, Sarah Walters, Koji Nozato, Jie Zhang, Tomoaki Kawakami, William Fischer, Lisa R. Latchney, Jennifer J. Hunter, Mina M. Chung, and David R. Williams Social Sciences Social Sciences On-demand high-capacity ride-sharing via dynamic trip-vehicle assignment  Javier Alonso-Mora, Samitha Samaranayake, Alex Wallar, Emilio Frazzoli, and Daniela Rus Sustainability Science Ancient human disturbances may be skewing our understanding of Amazonian forests Crystal N. H. McMichael, Frazer Matthews-Bird, William Farfan-Rios, and Kenneth J. Feeley Biological Sciences Anthropology Brain enlargement and dental reduction were not linked in hominin evolution Aida Gómez-Robles, Jeroen B. Smaers, Ralph L. Holloway, P. David Polly, and Bernard A. Wood Biochemistry Structural characterization of nonactive site, TrkA-selective kinase inhibitors Hua-Poo Su, Keith Rickert, Christine Burlein, Kartik Narayan, Marina Bukhtiyarova, Danielle M. Hurzy, Craig A. Stump, Xufang Zhang, John Reid, Alicja Krasowska-Zoladek, Srivanya Tummala, Jennifer M. Shipman, Maria Kornienko, Peter A. Lemaire, Daniel Krosky, Amanda Heller, Abdelghani Achab, Chad Chamberlin, Peter Saradjian, Berengere Sauvagnat, Xianshu Yang, Michael R. Ziebell, Elliott Nickbarg, John M. Sanders, Mark T. Bilodeau, Steven S. Carroll, Kevin J. Lumb, Stephen M. Soisson, Darrell A. Henze, and Andrew J. Cooke Resolution of single and double Holliday junction recombination intermediates by GEN1  Rajvee Shah Punatar, Maria Jose Martin, Haley D. M. Wyatt, Ying Wai Chan, and Stephen C. West MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus Yanqiang Wang, Huiling He, Wei Li, John Phay, Rulong Shen, Lianbo Yu, Baris Hancioglu, and Albert de la Chapelle Identification of NAD+ capped mRNAs in Saccharomyces cerevisiae  Robert W. Walters, Tyler Matheny, Laura S. Mizoue, Bhalchandra S. Rao, Denise Muhlrad, and Roy Parker Structural basis for regiospecific midazolam oxidation by human cytochrome P450 3A4 Irina F. Sevrioukova and Thomas L. Poulos Cell Biology SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes Anne Norris, Prasad Tammineni, Simon Wang, Julianne Gerdes, Alexandra Murr, Kelvin Y. Kwan, Qian Cai, and Barth D. Grant Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling  Andrew M. Kidger, Linda K. Rushworth, Julia Stellzig, Jane Davidson, Christopher J. Bryant, Cassidy Bayley, Edward Caddye, Tim Rogers, Stephen M. Keyse, and Christopher J. Caunt Matrix stiffening promotes a tumor vasculature phenotype  Francois Bordeleau, Brooke N. Mason, Emmanuel Macklin Lollis, Michael Mazzola, Matthew R. Zanotelli, Sahana Somasegar, Joseph P. Califano, Christine Montague, Danielle J. LaValley, John Huynh, Nuria Mencia-Trinchant, Yashira L. Negrón Abril, Duane C. Hassane, Lawrence J. Bonassar, Jonathan T. Butcher, Robert S. Weiss, and Cynthia A. Reinhart-King p53 pathway is involved in cell competition during mouse embryogenesis Guoxin Zhang, Yinyin Xie, Ying Zhou, Cong Xiang, Lai Chen, Chenxi Zhang, Xiaoshuang Hou, Jiong Chen, Hui Zong, and Geng Liu TRAIL-death receptor endocytosis and apoptosis are selectively regulated by dynamin-1 activation Carlos R. Reis, Ping-Hung Chen, Nawal Bendris, and Sandra L. Schmid Developmental Biology In vivo severity ranking of Ras pathway mutations associated with developmental disorders Granton A. Jindal, Yogesh Goyal, Kei Yamaya, Alan S. Futran, Iason Kountouridis, Courtney A. Balgobin, Trudi Schüpbach, Rebecca D. Burdine, and Stanislav Y. Shvartsman Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer  Zhi-Hui Chen, Reema Singh, Christian Cole, Hajara Mohammed Lawal, Christina Schilde, Melanie Febrer, Geoffrey J. Barton, and Pauline Schaap Ecology Ancient human disturbances may be skewing our understanding of Amazonian forests Crystal N. H. McMichael, Frazer Matthews-Bird, William Farfan-Rios, and Kenneth J. Feeley The global decline of cheetah Acinonyx jubatus and what it means for conservation  Sarah M. Durant, Nicholas Mitchell, Rosemary Groom, Nathalie Pettorelli, Audrey Ipavec, Andrew P. Jacobson, Rosie Woodroffe, Monika Böhm, Luke T. B. Hunter, Matthew S. Becker, Femke Broekhuis, Sultana Bashir, Leah Andresen, Ortwin Aschenborn, Mohammed Beddiaf, Farid Belbachir, Amel Belbachir-Bazi, Ali Berbash, Iracelma Brandao de Matos Machado, Christine Breitenmoser, Monica Chege, Deon Cilliers, Harriet Davies-Mostert, Amy J. Dickman, Fabiano Ezekiel, Mohammad S. Farhadinia, Paul Funston, Philipp Henschel, Jane Horgan, Hans H. de Iongh, Houman Jowkar, Rebecca Klein, Peter Andrew Lindsey, Laurie Marker, Kelly Marnewick, Joerg Melzheimer, Johnathan Merkle, Jassiel M'soka, Maurus Msuha, Helen O'Neill, Megan Parker, Gianetta Purchase, Samaila Sahailou, Yohanna Saidu, Abdoulkarim Samna, Anne Schmidt-Küntzel, Eda Selebatso, Etotépé A. Sogbohossou, Alaaeldin Soultan, Emma Stone, Esther van der Meer, R udie van Vuuren, Mary Wykstra, and Kim Young-Overton Evolution Higher rates of sex evolve during adaptation to more complex environments Pepijn Luijckx, Eddie Ka Ho Ho, Majid Gasim, Suyang Chen, Andrijana Stanic, Connor Yanchus, Yun Seong Kim, and Aneil F. Agrawal Dinosaur incubation periods directly determined from growth-line counts in embryonic teeth show reptilian-grade development  Gregory M. Erickson, Darla K. Zelenitsky, David Ian Kay, and Mark A. Norell Antibiotic stress selects against cooperation in the pathogenic bacterium Pseudomonas aeruginosa  Marie Vasse, Robert J. Noble, Andrei R. Akhmetzhanov, Clara Torres-Barceló, James Gurney, Simon Benateau, Claire Gougat-Barbera, Oliver Kaltz, and Michael E. Hochberg Genetics Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms  Michael H. Guo, Satish K. Nandakumar, Jacob C. Ulirsch, Seyedeh M. Zekavat, Jason D. Buenrostro, Pradeep Natarajan, Rany M. Salem, Roberto Chiarle, Mario Mitt, Mart Kals, Kalle Pärn, Krista Fischer, Lili Milani, Reedik Mägi, Priit Palta, Stacey B. Gabriel, Andres Metspalu, Eric S. Lander, Sekar Kathiresan, Joel N. Hirschhorn, Tõnu Esko, and Vijay G. Sankaran SIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences Eric J. Foss, Uyen Lao, Emily Dalrymple, Robin L. Adrianse, Taylor Loe, and Antonio Bedalov ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations  Amity R. Roberts, Louise H. Appleton, Adrian Cortes, Matteo Vecellio, Jonathan Lau, Laura Watts, Matthew A. Brown, and Paul Wordsworth Immunology and Inflammation GAS6 is a key homeostatic immunological regulator of host–commensal interactions in the oral mucosa Maria Nassar, Yaara Tabib, Tal Capucha, Gabriel Mizraji, Tsipora Nir, Meirav Pevsner-Fischer, Gili Zilberman-Schapira, Oded Heyman, Gabriel Nussbaum, Herve Bercovier, Asaf Wilensky, Eran Elinav, Tal Burstyn-Cohen, and Avi-Hai Hovav CD74 is a novel transcription regulator Naama Gil-Yarom, Lihi Radomir, Lital Sever, Matthias P. Kramer, Hadas Lewinsky, Chamutal Bornstein, Ronnie Blecher-Gonen, Zohar Barnett-Itzhaki, Vita Mirkin, Gilgi Friedlander, Lev Shvidel, Yair Herishanu, Elias J. Lolis, Shirly Becker-Herman, Ido Amit, and Idit Shachar Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia Jay R. Thiagarajah, Jeffrey Chang, Jeremy A. Goettel, Alan S. Verkman, and Wayne I. Lencer Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation William A. McEwan, Benjamin Falcon, Marina Vaysburd, Dean Clift, Adrian L. Oblak, Bernardino Ghetti, Michel Goedert, and Leo C. James Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis Peiwen Chen, Hao Zuo, Hu Xiong, Matthew J. Kolar, Qian Chu, Alan Saghatelian, Daniel J. Siegwart, and Yihong Wan Medical Sciences Imaging individual neurons in the retinal ganglion cell layer of the living eye   Ethan A. Rossi, Charles E. Granger, Robin Sharma, Qiang Yang, Kenichi Saito, Christina Schwarz, Sarah Walters, Koji Nozato, Jie Zhang, Tomoaki Kawakami, William Fischer, Lisa R. Latchney, Jennifer J. Hunter, Mina M. Chung, and David R. Williams Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation Zhaowei Tu, Mustafa Bilal Bayazit, Hongbin Liu, Jingjing Zhang, Kiran Busayavalasa, Sanjiv Risal, Jingchen Shao, Ande Satyanarayana, Vincenzo Coppola, Lino Tessarollo, Meenakshi Singh, Chunwei Zheng, Chunsheng Han, Zijiang Chen, Philipp Kaldis, Jan-Åke Gustafsson, and Kui Liu Microbiology Cell morphology drives spatial patterning in microbial communities William P. J. Smith, Yohan Davit, James M. Osborne, Wook Kim, Kevin R. Foster, and Joe M. Pitt-Francis Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges Gerald Lackner, Eike Edzard Peters, Eric J. N. Helfrich, and Jörn Piel Diverse evolutionary patterns of pneumococcal antigens identified by pangenome-wide immunological screening Nicholas J. Croucher, Joseph J. Campo, Timothy Q. Le, Xiaowu Liang, Stephen D. Bentley, William P. Hanage, and Marc Lipsitch Impact of short-chain galactooligosaccharides on the gut microbiome of lactose-intolerant individuals  M. Andrea Azcarate-Peril, Andrew J. Ritter, Dennis Savaiano, Andrea Monteagudo-Mera, Carlton Anderson, Scott T. Magness, and Todd R. Klaenhammer Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast  Ge Li, Melissa Poulsen, Csaba Fenyvuesvolgyi, Yoko Yashiroda, Minoru Yoshida, J. Marc Simard, Robert C. Gallo, and Richard Y. Zhao Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure  Cyril Le Nouën, Thomas McCarty, Michael Brown, Melissa Laird Smith, Roberto Lleras, Michael A. Dolan, Masfique Mehedi, Lijuan Yang, Cindy Luongo, Bo Liang, Shirin Munir, Joshua M. DiNapoli, Steffen Mueller, Eckard Wimmer, Peter L. Collins, and Ursula J. Buchholz Cryo-EM study of slow bee paralysis virus at low pH reveals iflavirus genome release mechanism  Sergei Kalynych, Tibor Füzik, Antonín Přidal, Joachim de Miranda, and Pavel Plevka Neuroscience Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity  Minshu Li, Zhiguo Li, Yang Yao, Wei-Na Jin, Kristofer Wood, Qiang Liu, Fu-Dong Shi, and Junwei Hao REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation–differentiation balance in the developing brain Caitlin E. Monaghan, Tamilla Nechiporuk, Sophia Jeng, Shannon K. McWeeney, Jianxun Wang, Michael G. Rosenfeld, and Gail Mandel Contribution of propriospinal neurons to recovery of hand dexterity after corticospinal tract lesions in monkeys Takamichi Tohyama, Masaharu Kinoshita, Kenta Kobayashi, Kaoru Isa, Dai Watanabe, Kazuto Kobayashi, Meigen Liu, and Tadashi Isa Physiology Stochastic initiation and termination of calcium-mediated triggered activity in cardiac myocytes  Zhen Song, Zhilin Qu, and Alain Karma Tbx20 controls the expression of the KCNH2 gene and of hERG channels Ricardo Caballero, Raquel G. Utrilla, Irene Amorós, Marcos Matamoros, Marta Pérez-Hernández, David Tinaquero, Silvia Alfayate, Paloma Nieto-Marín, Guadalupe Guerrero-Serna, Qing-hua Liu, Roberto Ramos-Mondragón, Daniela Ponce-Balbuena, Todd Herron, Katherine F. Campbell, David Filgueiras-Rama, Rafael Peinado, José L. López-Sendón, José Jalife, Eva Delpón, and Juan Tamargo Plant Biology ATG9 regulates autophagosome progression from the endoplasmic reticulum in Arabidopsis Xiaohong Zhuang, Kin Pan Chung, Yong Cui, Weili Lin, Caiji Gao, Byung-Ho Kang, and Liwen Jiang Corrections (Online Only) Correction for Novack-Gottshall, Love, not war, drove the Mesozoic marine revolution Correction for Lin et al., DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure