iScience: June 2024 (Volume 27, Issue 6)

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Jun 21, 2024 Vol. 27, Iss. 6 Open Access Website Table of Contents Online Now Archive

Highlights Announcements Follow us on LinkedIn Join our community on LinkedIn and stay updated with the latest and most exciting research. Trends Voices on SDGs: Affordable and clean energy View the new collection focused on the UN Sustainable Development Goal of affordable and clean energy. Call for papers: Joint special issue on brain-body interactions We are interested in studies at the intersection of neuroscience and broader biological systems Navigating the Pyrocene On July 11, join experts as they discuss managing fire risk in a warming world.

Table of Contents Backstory From cells to cars: Developing an electrochemical techniques and diagnostics course for new battery engineers Wesley Chang, Matthieu Dubarry, Jeffrey S. Lowe, Shannon Reed Reviews Optimized lipid nanoparticles (LNPs) for organ-selective nucleic acids delivery in vivo Tian Zhang, Han Yin, Yu Li, Haiyin Yang, Kun Ge, Jinchao Zhang, Qing Yuan, Xuyan Dai, Abid Naeem, Yuhua Weng, Yuanyu Huang, Xing-Jie Liang Drug delivery system; Nanoparticles; Nucleic acids Two-dimensional materials and their applications in fuel cells Zeyu Lu, Erbo Zhao, Chao Zhang, Chen Chen Electrochemical materials science; Materials science; Nanomaterials; Energy materials The role of yes activated protein (YAP) in melanoma metastasis Andrew Leask, John Nguyen, Angha Naik, Pratyusha Chitturi, Bruce L. Riser Molecular biology; Cell biology; Cancer Catalytic conversion of chitin-based biomass to nitrogen-containing chemicals Xinlei Ji, Yufeng Zhao, Matthew Y. Lui, László T. Mika, Xi Chen Catalysis; Chemical energy Unveiling the intratumoral microbiota within cancer landscapes Shusheng Che, Zhiyong Yan, Yugong Feng, Hai Zhao Cancer; Microbiology; Microbiome; Microenvironment Manufacturing and validation of small-diameter vascular grafts: A mini review Deyanira Hernandez-Sanchez, Maxime Comtois-Bona, Marcelo Muñoz, Marc Ruel, Erik J. Suuronen, Emilio I. Alarcon Cardiovascular medicine; Bioengineering; Tissue engineering; Biomaterials Fine nanostructure design of metal chalcogenide conversion-based cathode materials for rechargeable magnesium batteries Wenxing Miao, Hui Peng, Shuzhen Cui, Jingtian Zeng, Guofu Ma, Lei Zhu, Ziqiang Lei, Yuxi Xu Applied sciences; Materials science; Nanomaterials Design principles and therapeutic applications of novel synthetic WNT signaling agonists Yorick Post, Chenggang Lu, Russell B. Fletcher, Wen-Chen Yeh, Huy Nguyen, Sung-Jin Lee, Yang Li Molecular medicine; Cell biology Principles and research progress of physical prevention and control technologies for algae in eutrophic water Yuyao Wang, Yuanrong Zhu, Kuo Wang, Yidan Tan, Xiaojie Bing, Juan Jiang, Wen Fang, Liang Chen, Haiqing Liao Environmental science; Water resources engineering; Environmental engineering Recent advances in dynamic reconstruction of electrocatalysts for carbon dioxide reduction Jianfang Zhang, Shuai Xia, Yan Wang, Jingjie Wu, Yucheng Wu Catalysis; Engineering; Materials science Aseasonal, undirected migration in insects: 'Invisible' but common Thomas W. Sappington Environmental science; Ecology; Entomology Organoids as regenerative medicine for inflammatory bowel disease Alexander Hammerhøj, Deepavali Chakravarti, Toshiro Sato, Kim Bak Jensen, Ole Haagen Nielsen Molecular biology; Immunology; Cell biology; Stem cells research Monoclonal antibody biosimilars for cancer treatment Linda N. Broer, Daan G. Knapen, Derk-Jan A. de Groot, Peter G.M. Mol, Jos G.W. Kosterink, Elisabeth G.E. de Vries, Marjolijn N. Lub-de Hooge Health sciences; Biological sciences; Immunology; Cancer Hallmarks of cancer resistance Muhammad Tufail, Jia-Ju Hu, Jie Liang, Cai-Yun He, Wen-Dong Wan, Yu-Qi Huang, Can-Hua Jiang, Hong Wu, Ning Li Health sciences; Microenvironment; Biological sciences; Molecular biology; Epigenetics; Cancer. Perspectives Overcoming barriers to improved decision-making for battery deployment in the clean energy transition Brian Tarroja, Julie M. Schoenung, Oladele Ogunseitan, Alissa Kendall, Yang Qiu, Timothy Malloy, Jens Peters, J. Mijin Cha, Dustin Mulvaney, Oliver Heidrich, Manuel Baumann Electrochemical energy storage; Energy policy; Engineering AI and climate resilience governance Sara Mehryar, Vahid Yazdanpanah, Jeffrey Tong Natural sciences; Earth sciences; Environmental science; Environmental policy; Social sciences Articles Enzymatic depletion of circulating glutamine is immunosuppressive in cancers Monish Kumar, Ankita Leekha, Suman Nandy, Rohan Kulkarni, Melisa Martinez-Paniagua, K. M. Samiur Rahman Sefat, Richard C. Willson, Navin Varadarajan Molecular biology; Immunity; Cancer Photoreceptors for immediate effects of light on circadian behavior Daniel Bidell, Natalie-Danielle Feige, Tilman Triphan, Claudia Müller, Dennis Pauls, Charlotte Helfrich-Förster, Mareike Selcho Biological sciences; Entomology; Neuroscience DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in mice Xiaoke Ge, Bram Slütter, Joost M. Lambooij, Enchen Zhou, Zhixiong Ying, Ceren Agirman, Marieke Heijink, Antoine Rimbert, Bruno Guigas, Johan Kuiper, Christoph Müller, Franz Bracher, Martin Giera, Sander Kooijman, Patrick C.N. Rensen, Yanan Wang, Milena Schönke Cardiovascular medicine; Cellular physiology; Molecular genetics Unraveling biochemical spatial patterns: Machine learning approaches to the inverse problem of stationary Turing patterns Antonio Matas-Gil, Robert G. Endres Biochemistry; Machine learning Photothermally carbonized natural kelp for hydrovoltaic power generation Daewoong Kim, Jakyung Eun, Sangmin Jeon Chemistry; Chemical engineering; Electrochemistry; Electrochemical energy production. Ovulation provides excessive coagulation and hepatocyte growth factor signals to cause postoperative intraabdominal adhesions Vaishnavi Seenan, Che-Fang Hsu, Kanchana Subramani, Pao-Chu Chen, Dah-Ching Ding, Tang-Yuan Chu Surgery; Cellular physiology; Female reproductive endocrinology Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway Chuang Xi, Guoqiang Zhang, Nan Sun, Mengyue Liu, Nianting Ju, Chentian Shen, Hongjun Song, Quanyong Luo, Zhongling Qiu Phytopharmacy; Molecular biology; Cell biology; Cancer Nuclei-level prior knowledge constrained multiple instance learning for breast histopathology whole slide image classification Xunping Wang, Wei Yuan Bioinformatics; Machine learning Sarcoma_CellminerCDB: A tool to interrogate the genomic and functional characteristics of a comprehensive collection of sarcoma cell lines Camille Tlemsani, Christine M. Heske, Fathi Elloumi, Lorinc Pongor, Prashant Khandagale, Sudhir Varma, Augustin Luna, Paul S. Meltzer, Javed Khan, William C. Reinhold, Yves Pommier Cell biology; Cancer systems biology; Cancer; Genomics; Proteomics ; Transcriptomics Localizing 3D motion through the fingertips: Following in the footsteps of elephants Adi Snir, Katarzyna Cieśla, Gizem Ozdemir, Rotem Vekslar, Amir Amedi Biological sciences; Neuroscience; Techniques in neuroscience hESC- and hiPSC-derived Schwann cells are molecularly comparable and functionally equivalent Kathryn R. Moss, Ruifa Mi, Riki Kawaguchi, Jeffrey T. Ehmsen, Qiang Shi, Paula I. Vargas, Bipasha Mukherjee-Clavin, Gabsang Lee, Ahmet Höke Neuroscience; Cell biology; Stem cells research; Transcriptomics RNA editing in host lncRNAs as potential modulator in SARS-CoV-2 variants-host immune response dynamics Partha Chattopadhyay, Priyanka Mehta, Kanika, Pallavi Mishra, Chinky Shiu Chen Liu, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey Biological sciences; Molecular biology; Immune response; Virology Enhanced quantum secret sharing protocol for anonymous secure communication utilizing W states Guo-Dong Li, Wen-Chuan Cheng, Qing-Le Wang, Long Cheng, Ying Mao, Heng-Yue Jia Quantum measurement; Applied sciences; Computer security and privacy SENP1 facilitates OM-MSC differentiation through activating OPTN-mediated mitophagy to mitigate the neurologic impairment following ICH Jun He, Jun Peng, You Li, Junwen Jiang, Jiameng Li, Long Lin, Jian Wang, Ying Xia Biological sciences; Cell biology; Molecular biology; Stem cells research Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma Ruizhi Zhang, Jingjing Dai, Feifan Yao, Suiqing Zhou, Wei Huang, Jiali Xu, Kai Yu, Yining Chen, Boqiang Fan, Liren Zhang, Jing Xu, Qing Li Molecular biology; Immunology; Cancer. Mitochondrial clearance and increased HSF-1 activity are coupled to promote longevity in fasted Caenorhabditis elegans Nikolaos Tataridas-Pallas, Yahyah Aman, Rhianna Williams, Hannah Chapman, Kevin J.H. Cheng, Casandra Gomez-Paredes, Gillian P. Bates, John Labbadia Biological sciences; Physiology; Molecular biology; Cell biology RAD21 deficiency drives corneal to scleral differentiation fate switching via upregulating WNT9B Hongyan Liu, Benxiang Qi, Guanghui Liu, Haoyun Duan, Zongyi Li, Zhaoying Shi, Yonglong Chen, Wai Kit Chu, Qingjun Zhou, Bi Ning Zhang Cell biology; Developmental biology The relationship between gastrointestinal symptoms in FGID patients and D-type personality and emotion regulation strategies Xin-Xin Ma, Zheng-Hua Xiao, Wei Chen, Shou-Ying Zhao Gastroenterology; Psychosocial factor Intracellular delivery of oncolytic viruses with engineered Salmonella causes viral replication and cell death Shradha Khanduja, Shoshana M.K. Bloom, Vishnu Raman, Chinmay P. Deshpande, Christopher L. Hall, Neil S. Forbes Microbiology; Bacteriology; Virology; Cell biology