iScience: January 2023 (Volume 26, Issue 1)

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Jan 20, 2023
Vol. 26, Iss. 1
Open Access

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Table of Contents

Backstory

An interdisciplinary effort to understand chemical organizations at the origin of life
C. Jeancolas, A.Y. Singh, S. Jain, S. Krishna, P. Nghe
Reviews

Pain, from perception to action: A computational perspective
Zhe Sage Chen, Jing Wang

Bioinformatics; Neuroscience; Sensory neuroscience

In vitro and in vivo models for monkeypox
Rafael Borges Rosa, Emilene Ferreira de Castro, Murilo Vieira da Silva, Denise Caroline Paiva Ferreira, Ana Carolina Gomes Jardim, Igor Andrade Santos, Mikaela dos Santos Marinho, Flávia Batista Ferreira França, Lindomar José Pena

Virology

Engineered organoids in oral and maxillofacial regeneration
Yu Wang, Yao Sun

Biological sciences; Biomedical engineering; Materials science; Biomaterials

Covalently triggered self-assembly of peptide-based nanodrugs for cancer theranostics
Yamei Liu, Ruirui Xing, Junbai Li, Xuehai Yan

Drugs; Molecular self-assembly; Nanotechnology; Cancer

Survival in desert: Extreme water adaptations and bioinspired structural designs
Guandi He, Chengqi Zhang, Zhichao Dong

Earth sciences; Environmental management

Supramolecular enzyme-mimicking catalysts self-assembled from peptides
Qing Liu, Akinori Kuzuya, Zhen-Gang Wang

Biomolecules; Chemistry; Peptides; Supramolecular chemistry

Advanced perspectives on MXene composite nanomaterials: Types synthetic methods, thermal energy utilization and 3D-printed techniques
Yuanlong Cui, Jie Zhu, Hui Tong, Ran Zou

Materials science; Nanomaterials

A survey of mechanical antennas applied for low-frequency transmitting
Yong Cui, Chen Wang, Xiao Song, Ming Wu, Qianyun Zhang, Haiwen Yuan, Zhihong Yuan

Telecommunication engineering; Electromechanical System; Mechanical systems

An overview of deterministic and probabilistic forecasting methods of wind energy
Yuying Xie, Chaoshun Li, Mengying Li, Fangjie Liu, Meruyert Taukenova

Energy modeling, energy engineering, energy systems

ABO blood group antigens and differential glycan expression: Perspective on the evolution of common human enzyme deficiencies
Ryan Philip Jajosky, Shang-Chuen Wu, Leon Zheng, Audrey N. Jajosky, Philip G. Jajosky, Cassandra D. Josephson, Marie A. Hollenhorst, Robert Sackstein, Richard D. Cummings, Connie M. Arthur, Sean R. Stowell

Biological sciences; Biochemistry; Evolutionary biology

Mechanobiology: A landscape for reinterpreting stem cell heterogeneity and regenerative potential in diseased tissues
Riccardo Tassinari, Elena Olivi, Claudia Cavallini, Valentina Taglioli, Chiara Zannini, Martina Marcuzzi, Oleksandra Fedchenko, Carlo Ventura

Mechanobiology; Cell biology

Candida albicans-enteric viral interactions—The prostaglandin E2 connection and host immune responses
Bonang M. Mochochoko, Carolina H. Pohl, Hester G. O’Neill

Pathogenic organism; Biochemistry; Microbiology

Integration of daytime radiative cooling and solar heating
Xiuqiang Li, Sujin Shao, Meijiao Huang, Shuyuan Zhang, Wanlin Guo

Energy engineering; Energy application; Energy materials

Environmental and health risks of perovskite solar modules: Case for better test standards and risk mitigation solutions
Christa E. Torrence, Cara S. Libby, Wanyi Nie, Joshua S. Stein

Applied sciences; Environmental toxicology; Toxicology

Large-scale multimodal surface neural interfaces for primates
Tiphaine Belloir, Sergio Montalvo-Vargo, Zabir Ahmed, Devon J. Griggs, Shawn Fisher, Timothy Brown, Maysamreza Chamanzar, Azadeh Yazdan-Shahmorad

Optoelectronics; Neuroscience

Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH
Gideon G. Kang, Natalie L. Trevaskis, Andrew J. Murphy, Mark A. Febbraio

Hepatology, Biological sciences, Physiology, Human metabolism, Immunology

Articles

Ring-stage growth arrest: Metabolic basis of artemisinin tolerance in Plasmodium falciparum
Xinyu Yu, Changhong Wang, Yuemeng Zhao, Jianxia Tang, Meng Zhu, Lucien Platon, Richard Culleton, Guoding Zhu, Didier Ménard, Qingfeng Zhang, Jun Cao

Multidrug resistant organisms; Parasitology

Chimeric RNA RRM2-C2orf48 plays an oncogenic role in the development of NNK-induced lung cancer
Jiazhen Zhou, Xinchao Guan, Enwu Xu, Jiaxin Zhou, Rui Xiong, Qiaoyuan Yang

Molecular biology; Cell biology; Cancer

Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins
Chuandi Yu, Wen Ding, Lei Zhu, Yuhang Zhou, Yingkui Dong, Ling Li, Juanjuan Liu, Yizhuo Wang, Zehua Li, Lina Zhu, FaJun Chen, Maosen Ruan, Dongming Qian, Yujuan Wang, Bo Wu, Huangtao Xu, Ming Li, Yunchen Bi, Hao Wang, Weiqian Wang, Peng Chao, Lei Xing, Bing Shen, Han Dai, Lisha Zha, Hongxin Zhao, Junfeng Wang

Virology; Nanoparticles

Aberrant cortical projections to amygdala GABAergic neurons contribute to developmental circuit dysfunction following early life stress
Joni Haikonen, Jonas Englund, Shyrley Paola Amarilla, Zoia Kharybina, Alexandra Shintyapina, Kristel Kegler, Marta Saez Garcia, Tsvetomira Atanasova, Tomi Taira, Henrike Hartung, Sari E. Lauri

Behavioral neuroscience; Developmental neuroscience; Systems neuroscience

“Stealing fire or stacking knowledge” by machine intelligence to model link prediction in complex networks
Alessandro Muscoloni, Carlo Vittorio Cannistraci

Artificial intelligence; Network

A multi-omics based anti-inflammatory immune signature characterizes long COVID-19 syndrome
Johannes J. Kovarik, Andrea Bileck, Gerhard Hagn, Samuel M. Meier-Menches, Tobias Frey, Anna Kaempf, Marlene Hollenstein, Tarik Shoumariyeh, Lukas Skos, Birgit Reiter, Marlene C. Gerner, Andreas Spannbauer, Ena Hasimbegovic, Doreen Schmidl, Gerhard Garhöfer, Mariann Gyöngyösi, Klaus G. Schmetterer, Christopher Gerner

Immunology; Immune response; Omics

A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
Emily Brookes, Braulio Martinez De La Cruz, Paraskevi Boulasiki, Ho Yu Alan Au, Wazeer Varsally, Christopher Barrington, Suzana Hadjur, Antonella Riccio

Biological sciences; Neuroscience; Molecular neuroscience; Developmental neuroscience

Feasibility of using AI to auto-catch responsible frames in ultrasound screening for breast cancer diagnosis
Jing Chen, Yitao Jiang, Keen Yang, Xiuqin Ye, Chen Cui, Siyuan Shi, Huaiyu Wu, Hongtian Tian, Di Song, Jincao Yao, Liping Wang, Sijing Huang, Jinfeng Xu, Dong Xu, Fajin Dong

Computer-aided diagnosis method; Cancer; Artificial intelligence

Wnt antagonism without TGFβ induces rapid MSC chondrogenesis via increasing AJ interactions and restricting lineage commitment
Chen-Chan Hsieh, B. Linju Yen, Chia-Chi Chang, Pei-Ju Hsu, Yu-Wei Lee, Men-Luh Yen, Shaw-Fang Yet, Linyi Chen

Bioengineering; Biological sciences; Molecular medicine; Tissue engineering

Conformational stability of SARS-CoV-2 glycoprotein spike variants
Hiam R.S. Arruda, Tulio M. Lima, Renata G.F. Alvim, Fernanda B.A. Victorio, Daniel P.B. Abreu, Federico F. Marsili, Karen D. Cruz, Mayra A. Marques, Patricia Sosa-Acosta, Mauricio Quinones-Vega, Jéssica de S. Guedes, Fábio C.S. Nogueira, Jerson L. Silva, Leda R. Castilho, Guilherme A.P. de Oliveira

Biochemistry; Virology; Structural biology; Protein structure aspects

Rickettsial pathogen inhibits tick cell death through tryptophan metabolite mediated activation of p38 MAP kinase
Prachi Namjoshi, Mustapha Dahmani, Hameeda Sultana, Girish Neelakanta

Biological sciences; Molecular biology; Microbiology; Parasitology

Decoding the coupled decision-making of the epithelial-mesenchymal transition and metabolic reprogramming in cancer
Madeline Galbraith, Herbert Levine, José N. Onuchic, Dongya Jia

Cancer systems biology; Metabolic flux analysis

Mitigating climate change to alleviate economic inequality under the Paris Agreement
Yun Tang, Hongbo Duan, Shiyun Yu

Environmental policy; Energy resources; Energy policy; Economics

Genetic influences on human blood metabolites in the Japanese population
Takeshi Iwasaki, Yoichiro Kamatani, Kazuhiro Sonomura, Shuji Kawaguchi, Takahisa Kawaguchi, Meiko Takahashi, Koichiro Ohmura, Taka-Aki Sato, Fumihiko Matsuda

Human Genetics; Human metabolism; Human Physiology

Epilepsy gene prickle ensures neuropil glial ensheathment through regulating cell adhesion molecules
Yanbo Chen, Tong-Tong Liu, Mengxia Niu, Xiaoting Li, Xinwei Wang, Tong Liu, Yan Li

Cell biology; Molecular physiology; Neuroscience

Ad26.COV2.S priming provided a solid immunological base for mRNA-based COVID-19 booster vaccination
Daryl Geers, Roos S.G. Sablerolles, Debbie van Baarle, Neeltje A. Kootstra, Wim J.R. Rietdijk, Katharina S. Schmitz, Lennert Gommers, Susanne Bogers, Nella J. Nieuwkoop, Laura L.A. van Dijk, Eva van Haren, Melvin Lafeber, Virgil A.S.H. Dalm, Abraham Goorhuis, Douwe F. Postma, Leo G. Visser, Anke L.W. Huckriede, Alessandro Sette, Alba Grifoni, Rik L. de Swart, Marion P.G. Koopmans, P. Hugo M. van der Kuy, Corine H. GeurtsvanKessel, Rory D. de Vries

Health sciences; Immunology; Immune response; Virology

Universal drivers of cheese microbiomes
Rine Christopher Reuben, Désirée Langer, Nico Eisenhauer, Stephanie D. Jurburg

Microbiology; Microbiome; Food microbiology

Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation
Antonio Bouthelier, Lucía Fernández-Arroyo, Claudia Mesa-Ciller, Danay Cibrian, Noa Beatriz Martín-Cófreces, Raquel Castillo-González, Macarena Calero, Diego Herráez-Aguilar, Andrea Guajardo-Grence, Ana María Pacheco, Ana Marcos-Jiménez, Borja Quiroga, Marta Morado, Francisco Monroy, Cecilia Muñoz-Calleja, Francisco Sánchez-Madrid, Andrés A. Urrutia, Julián Aragonés

Molecular physiology; Cell biology.

Optimal high-throughput virtual screening pipeline for efficient selection of redox-active organic materials
Hyun-Myung Woo, Omar Allam, Junhe Chen, Seung Soon Jang, Byung-Jun Yoon

Organic chemistry; Materials science

A synthetic human 3D in vitro lymphoid model enhancing B-cell survival and functional differentiation
Maaike V.J. Braham, Rob S. van Binnendijk, Anne-Marie M. Buisman, Reina E. Mebius, Jelle de Wit, Cécile A.C.M. van Els

Biological sciences; Bioengineering; Cell engineering; Tissue Engineering

N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells
Tetsuya Hirata, Yoichiro Harada, Koichiro M. Hirosawa, Yuko Tokoro, Kenichi G.N. Suzuki, Yasuhiko Kizuka

Biochemistry; Cell biology; Cancer

Assessment of stromal SCD-induced drug resistance of PDAC using 3D-printed zPDX model chips
Chuntao Wu, Beiyuan Hu, Lei Wang, Xia Wu, Haitao Gu, Hanguang Dong, Jiuliang Yan, Zihao Qi, Qi Zhang, Huan Chen, Bo Yu, Sheng Hu, Yu Qian, Shuang Dong, Qiang Li, Xu Wang, Jiang Long

Cancer; Lipid; Microenvironment

Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations
Martina Sgritta, Beatrice Vignoli, Domenico Pimpinella, Marilena Griguoli, Spartaco Santi, Andrzej Bialowas, Grzegorz Wiera, Paola Zacchi, Francesca Malerba, Cristina Marchetti, Marco Canossa, Enrico Cherubini

Neuroscience; Developmental neuroscience; Cellular neuroscience

Early alveolar epithelial cell necrosis is a potential driver of COVID-19-induced acute respiratory distress syndrome
Kentaro Tojo, Natsuhiro Yamamoto, Nao Tamada, Takahiro Mihara, Miyo Abe, Mototsugu Nishii, Ichiro Takeuchi, Takahisa Goto

Health sciences; Pathophysiology; Cell biology

Single-cell RNA sequencing uncovers dynamic roadmap and cell-cell communication during buffalo spermatogenesis
Liangfeng Huang, Junjun Zhang, Pengfei Zhang, Xingchen Huang, Weihan Yang, Runfeng Liu, Qinqiang Sun, Yangqing Lu, Ming Zhang, Qiang Fu

Cell biology; Cell; Omics; Transcriptomics

Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists
Yasuha Arai, Itaru Yamanaka, Toru Okamoto, Ayana Isobe, Naomi Nakai, Naoko Kamimura, Tatsuya Suzuki, Tomo Daidoji, Takao Ono, Takaaki Nakaya, Kazuhiko Matsumoto, Daisuke Okuzaki, Yohei Watanabe

immunology and virology

Cortical feedback modulates distinct critical period development in mouse visual thalamus
Na Li, Qiong Liu, Yimu Zhang, Zhongyi Yang, Xuefeng Shi, Yu Gu

Biological sciences; Developmental neuroscience; Sensory neuroscience

Cellular resistance to an oncolytic virus is driven by chronic activation of innate immunity
Alejandra Larrieux, Rafael Sanjuán

Molecular physiology; Immunology; Virology

Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality
Hiroaki Kobayashi, Kenji Takemoto, Makoto Sanbo, Masumi Hirabayashi, Takahiro Hirabayashi, Teruyoshi Hirayama, Hiroshi Kiyonari, Takaya Abe, Takeshi Yagi

Cell biology; Developmental genetics; Neuroscience

baz1b loss-of-function in zebrafish produces phenotypic alterations consistent with the domestication syndrome
Jose V. Torres-Pérez, Sofia Anagianni, Aleksandra M. Mech, William Havelange, Judit García-González, Scott E. Fraser, Giorgio Vallortigara, Caroline H. Brennan

Molecular physiology; Behavioral neuroscience

Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape
Roberta Marzi, Jessica Bassi, Chiara Silacci-Fregni, Istvan Bartha, Francesco Muoio, Katja Culap, Nicole Sprugasci, Gloria Lombardo, Christian Saliba, Elisabetta Cameroni, Antonino Cassotta, Jun Siong Low, Alexandra C. Walls, Matthew McCallum, M. Alejandra Tortorici, John E. Bowen, Exequiel A. Dellota Jr., Josh R. Dillen, Nadine Czudnochowski, Laura Pertusini, Tatiana Terrot, Valentino Lepori, Maciej Tarkowski, Agostino Riva, Maira Biggiogero, Alessandra Franzetti-Pellanda, Christian Garzoni, Paolo Ferrari, Alessandro Ceschi, Olivier Giannini, Colin Havenar-Daughton, Amalio Telenti, Ann Arvin, Herbert W. Virgin, Federica Sallusto, David Veesler, Antonio Lanzavecchia, Davide Corti, Luca Piccoli

Immunology; Virology

Quinoa husk peptides reduce melanin content via Akt signaling and apoptosis pathways
Caijing Han, Bingjie Lin, Xinyu Huang, Zhaojie Mao, Xiaoting Kong, Lei Fang, Peng Xue, Anning Wang, Fengxiang Zhang

Medical biochemistry; Plant biochemistry; Cellular physiology

The scaffolding function of LSD1/KDM1A reinforces a negative feedback loop to repress stem cell gene expression during primitive hematopoiesis
Mattie J. Casey, Alexandra M. Call, Annika V. Thorpe, Cicely A. Jette, Michael E. Engel, Rodney A. Stewart

Molecular biology; Molecular interaction; Cell biology; Stem cells research

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