Viral Variants: How mutations affect function AND more New articles from eLife – July 1, 2024

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New articles from eLife

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MAGAZINE MICROBIOLOGY AND INFECTIOUS DISEASE, STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS How mutations affect function Thomas Kuhlman A new study reveals how naturally occurring mutations affect the biophysical properties of nucleocapsid proteins in SARS-CoV-2.

REVIEWED PREPRINTS NEUROSCIENCE Single cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes GVS Devakinandan, Mark Terasaki, Adish Dani STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts Po-Lin Chiu, Juan D. Orjuela ... Thomas Walz NEUROSCIENCE Single neurons and networks in the claustrum integrate input from widespread cortical sources Andrew M. Shelton, David K. Oliver ... Adam M. Packer COMPUTATIONAL AND SYSTEMS BIOLOGY Perturbation-response analysis of in silico metabolic dynamics in nonlinear regime: Hard-coded responsiveness in the cofactors and network sparsity Yusuke Himeoka, Chikara Furusawa NEUROSCIENCE A deep learning framework for automated and generalized synaptic event analysis Philipp S. O’Neill, Martín Baccino-Calace ... Igor Delvendahl NEUROSCIENCE Slow kinesin-dependent microtubular transport facilitates ribbon synapse assembly in developing cochlear inner hair cells Roos Anouk Voorn, Michael Sternbach ... Christian Vogl NEUROSCIENCE Pinging the Hidden Attentional Priority Map: Suppression Needs Attention Changrun Huang, Dirk van Moorselaar ... Jan Theeuwes NEUROSCIENCE Sub-cone visual resolution by active, adaptive sampling in the human foveola Jenny L. Witten, Veronika Lukyanova, Wolf M. Harmening NEUROSCIENCE, COMPUTATIONAL AND SYSTEMS BIOLOGY The Recurrent Temporal Restricted Boltzmann Machine Captures Neural Assembly Dynamics in Whole-brain Activity Sebastian Quiroz Monnens, Casper Peters ... Bernhard Englitz NEUROSCIENCE Using recurrent neural network to estimate irreducible stochasticity in human choice-behavior Yoav Ger, Moni Shahar, Nitzan Shahar CELL BIOLOGY, NEUROSCIENCE Presynaptic Rac1 in the hippocampus selectively regulates working memory Jaebin Kim, Edwin Bustamante ... Scott H. Soderling DEVELOPMENTAL BIOLOGY, NEUROSCIENCE Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development Saman Hussain, Katherine Pinter ... Katie Kindt DEVELOPMENTAL BIOLOGY, NEUROSCIENCE Energetic Demands Regulate Sleep-Wake Rhythm Circuit Development Amy R. Poe, Lucy Zhu ... Matthew S. Kayser NEUROSCIENCE Sex-dependent, lateralized engagement of anterior insular cortex inputs to the dorsolateral striatum in binge alcohol drinking David L. Haggerty, Brady K. Atwood BIOCHEMISTRY AND CHEMICAL BIOLOGY, CHROMOSOMES AND GENE EXPRESSION Human DDX6 regulates translation and decay of inefficiently translated mRNAs Ramona Weber, Lara Wohlbold, Chung-Te Chang NEUROSCIENCE The Spatial Frequency Representation Predicts Category Coding in the Inferior Temporal Cortex Ramin Toosi, Behnam Karami ... Mohammad-Reza A. Dehaqani GENETICS AND GENOMICS, CANCER BIOLOGY Circulating Small Extracellular Vesicle RNA Profiling for the Detection of T1a stage Colorectal Cancer and Precancerous Advanced Adenoma Li Min, Fanqin Bu ... Shutian Zhang NEUROSCIENCE The transformation of sensory to perceptual braille letter representations in the visually deprived brain Marleen Haupt, Monika Graumann ... Radoslaw M. Cichy NEUROSCIENCE Dynamic Gamma Modulation of Hippocampal Place Cells Predominates Development of Theta Sequences Ning Wang, Yimeng Wang ... Dong Ming CELL BIOLOGY Novel Mechanism for Tubular Injury in Nephropathic Cystinosis Swastika Sur, Maggie Kerwin ... Minnie M. Sarwal NEUROSCIENCE Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits Samyogita Hardikar, Brontë Mckeown ... Jonathan Smallwood NEUROSCIENCE Prediction error determines how memories are organized in the brain: a study of Pavlovian fear extinction in rats Nicholas G. W. Kennedy, Jessica C. Lee ... Nathan M. Holmes STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS Empowering AlphaFold2 for protein conformation selective drug discovery with AlphaFold2-RAVE Xinyu Gu, Akashnathan Aranganathan, Pratyush Tiwary CANCER BIOLOGY Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer Eugine Lee, Zeda Zhang ... Charles L. Sawyers NEUROSCIENCE Microprism-based two-photon imaging of the mouse inferior colliculus reveals novel organizational principles of the auditory midbrain Baher A. Ibrahim, Yoshitaka Shinagawa ... Daniel A. Llano BIOCHEMISTRY AND CHEMICAL BIOLOGY, STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS Observing one-divalent-metal-ion dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo Caleb Chang, Grace Zhou, Yang Gao DEVELOPMENTAL BIOLOGY, CANCER BIOLOGY VGLL2 and TEAD1 fusion proteins drive YAP/TAZ-independent transcription and tumorigenesis by engaging p300 Susu Guo, Xiaodi Hu ... Junhao Mao CELL BIOLOGY, DEVELOPMENTAL BIOLOGY Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development Divyesh Joshi, Preeti Jindal ... Maneesha S. Inamdar CHROMOSOMES AND GENE EXPRESSION, EVOLUTIONARY BIOLOGY The emergence and evolution of gene expression in genome regions replete with regulatory motifs Timothy Fuqua, Yiqiao Sun, Andreas Wagner NEUROSCIENCE Neurons in the ventral striatopallidal complex modulate lateral hypothalamic orexin/hypocretin neuron activity: Implications for reward-seeking Caitlin S. Mitchell, Aida Mohammadkhani ... Christopher V. Dayas CELL BIOLOGY Malatl fine-tunes bone homeostasis by orchestrating cellular crosstalk and the β-catenin-OPG/Jagged1 pathway Yongli Qin, Jumpei Shirakawa ... Baohong Zhao NEUROSCIENCE Homeostatic synaptic normalization optimizes learning in network models of neural population codes Jonathan Mayzel, Elad Schneidman GENETICS AND GENOMICS, EPIDEMIOLOGY AND GLOBAL HEALTH Systematic evaluation of multifactorial causal associations for Alzheimer’s disease and an interactive platform based on Mendelian randomization analysis — MRAD Tianyu Zhao, Hui Li ... Li Chen CELL BIOLOGY, NEUROSCIENCE Junctional Adhesion Molecule (JAM)-C recruitment of Pard3 and drebrin to cell contacts initiates neuron-glia recognition and layer-specific cell sorting in developing cerebella Liam P. Hallada, Abbas Shirinifard, David J Solecki MEDICINE, IMMUNOLOGY AND INFLAMMATION Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns Ole Bæk, Tik Muk ... Duc Ninh Nguyen ECOLOGY, EVOLUTIONARY BIOLOGY First evidence for the evolution of host manipulation by tumors during the long-term vertical transmission of tumor cells in Hydra oligactis Justine Boutry, Océane Rieu ... Frédéric Thomas STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS, COMPUTATIONAL AND SYSTEMS BIOLOGY MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations Johanna K. S. Tiemann, Magdalena Szczuka ... Pierre Poulain BIOCHEMISTRY AND CHEMICAL BIOLOGY, CELL BIOLOGY Pushed to the edge: hundreds of myosin 10s pack into filopodia and could cause traffic jams on actin Julia Shangguan, Ronald S. Rock