Research
Methylation variability and LINE-1 transcriptional activation in multiple myeloma Qianhui Wan, Amy Leung, Mahek Vinod Bhandari, Hiroyuki Kato, Joo Y Song and Dustin Schones
Genome Res. published 17 July 2026; doi:10.1101/gr.281420.125
Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer Alexandra Richey, Noel Kitchen, Craig M Rush, Jeffery M Vahrenkamp, Hosiana Abewe, Kyle S Osborne, Alex J Bott, Brian K Dalley, Jared Rutter and Jason Gertz
Genome Res. published 17 July 2026; doi:10.1101/gr.281792.125 Open Access
Evolution of an adaptive, inducible defensive trait in a model crustacean Zhixiong Deng, Sen Xu, Dengqing Li, Guo Yu, Swatantra Neupane, Li Wang, David Blair, Wei Hu, Adam Petrusek and Mingbo Yin
Genome Res. published 5 June 2026; doi:10.1101/gr.281631.125
Elevated DNA insertion rate in Cyanophora paradoxa reveals unique repair signature Marc Krasovec, Anna Lipzen, Nigel Grimsley, Gilles Mirambeau, Kerrie Barry, Igor V. Grigoriev and Gwenael Piganeau
Genome Res. published 12 June 2026; doi:10.1101/gr.281517.125
Genome-wide crossover analysis in the holocentric pantry moth reveals strong crossover assurance and interference during spermatogenesis LingSze Lee, Apratim Mitra, Leif Benner, Melania Bruno, Lorielle M. Raab, Rose K. Runyan, Emma Smith, Ryan K. Dale and Leah F. Rosin
Genome Res. published 16 July 2026; doi:10.1101/gr.281913.126 Open Access
Covariation of genetic and epigenetic divergence in barn swallows Sarah A. Mueller, Uthara Srinivasan, Zachary M. Laubach, Drew R. Schield, Jan A.C. von Rönn, Rebecca J. Safran and Jochen B.W. Wolf
Genome Res. published 16 June 2026; doi:10.1101/gr.281470.125
The impact of sex, age, and genetic ancestry on DNA methylation across tissues Winona Oliveros, Jose Miguel Ramirez, Maria Sopena-Rios, Pau Clavell-Revelles and Marta Mele
Genome Res. published 14 July 2026; doi:10.1101/gr.281428.125
Methods
Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks Zihuan Du, Xiaoyu Zhang, Qiang Zhang, Jing Li, Zhijie Cao, Ge Gao, Tao Lin, Dong Wang and Shuai Gao
Genome Res. published 22 July 2026; doi:10.1101/gr.281629.125
A unified analysis of cell-type- and trajectory-associated pathways in single-cell data using Phoenix Yudit Halperin, Daphna Nachmani and Michal Rabani
Genome Res. published 29 June 2026; doi:10.1101/gr.281411.125
Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI Peimeng Zhen, Han Shu, Bingtao Wang, Yongtian Wang, Jialu Hu, Jiajie Peng, Xuequn Shang, Tao Wang and Jing Chen
Genome Res. published 22 July 2026; doi:10.1101/gr.281568.125
ComicGTN infers disease-associated rare cell states from single-cell multiomic data using DNA sequence–augmented graph transformer networks Boran Yang, Jiao Hua, Guanghua Zhou, Yuhui Feng, Jing Qi, Yiyuan Guo, Danshu Sheng and Shuilin Jin
Genome Res. published 17 July 2026; doi:10.1101/gr.281661.125
A comparison of ancient DNA yields across ossicles and the petrous bone reveals the best preservation in the stapes and incus Ekin Sağlıcan, Arda Sevkar, Duygu Deniz Kazancı, Gonzalo Oteo-García, Sevgi Yorulmaz, Kıvılcım Başak Vural, Gökhan Çakan, Gökçen Adiloğlu, Duru Buldak, Güneş Duru, Aliye Öztan, Brenna Hassett, Nurcan Kayacan, Aslı Erim Özdoğan, Anders Götherström, Füsun Özer, Ömür Dilek Erdal, Yılmaz Selim Erdal and Mehmet Somel
Genome Res. published 11 June 2026; doi:10.1101/gr.281213.125
A sequence-based classifier distinguishes phenotype-associated genes from other gene models in plants Nikee Shrestha, Zhongjie Ji, Xiuru Dai, Pinghua Li and James C. Schnable
Genome Res. published 14 July 2026; doi:10.1101/gr.281802.125 Open Access
Resources
Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium Shigehiro Kuraku, Yawako W. Kawaguchi, Taiki Niwa, Ryo Misawa, Yohey Ogawa, Mitsutaka Kadota, Kazuhiro Saito, Waichiro Godo, Tatsuya Sakamoto, Wataru Takagi, Sachiko Isobe, Kenta Shirasawa and Akane Kawaguchi
Genome Res. published 16 June 2026; doi:10.1101/gr.281149.125
Complete sequencing of medaka genomes reveals the architecture of centromeric satellites, giant mobile elements, and sex chromosomes Yoshihiko Suzuki, Kazuki Ichikawa, Yusuke Inoue, Chie Owa, Haruka Kobayashi, Kenji Morikami, Ryohei Nakamura, Takafumi Ikeda, Manabu Fujie, Mayumi Kawamitsu, Nana Arakaki, Eugene W. Myers, Hiroyuki Aburatani, Yusuke Takehana, Masaru Matsuda, Kiyoshi Naruse, Shigehiro Kuraku, Hiroyuki Takeda and Shinichi Morishita
Genome Res. published 1 July 2026; doi:10.1101/gr.281813.125 Open Access
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