New articles from eLife – July 22, 2024

[Virtual Post Bioclues]

 

July 22, 2024 New articles from eLife In this LSE Impact Blog post, we discuss the rise of journals as holders of brand value over research quality, and how our industry could help escape this dynamic MAGAZINE STEM CELLS AND REGENERATIVE MEDICINE Counting blood precursors Sarah Duchamp de Chastaigne, Catherine M Sawai A new mathematical model can estimate the number of precursor cells that contribute to regenerating blood cells in mice. NEUROSCIENCE Time to get deep Max Schulz, Malte Wöstmann Asymmetries in the size of structures deep below the cortex explain how alpha oscillations in the brain respond to shifts in attention. REVIEWED PREPRINTS CELL BIOLOGY, STEM CELLS AND REGENERATIVE MEDICINE Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition Liyi Wang, Shiqi Liu ... Tizhong Shan CANCER BIOLOGY Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden Hyungtai Sim, Hyun Jung Park ... Murim Choi CHROMOSOMES AND GENE EXPRESSION, CANCER BIOLOGY The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma Ariunaa Bayanjargal, Cenny Taslim ... Emily R Theisen CHROMOSOMES AND GENE EXPRESSION, CANCER BIOLOGY Association with TFIIIC limits MYCN localization in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA Polymerase II Raphael Vidal, Eoin Leen ... Gabriele Büchel IMMUNOLOGY AND INFLAMMATION, MICROBIOLOGY AND INFECTIOUS DISEASE Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection Kely C Matteucci, Patricia A Assis ... Ricardo T Gazzinelli IMMUNOLOGY AND INFLAMMATION Thymic self-recognition-mediated TCR signal strength modulates antigen-specific CD8+ T cell pathogenicity in non-obese diabetic mice Chia-Lo Ho, Li-Tzu Yeh ... Huey-Kang Sytwu CANCER BIOLOGY Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment Youyou Zhang, Mu Xu ... Lin Zhang GENETICS AND GENOMICS Tradeoffs in Modeling Context Dependency in Complex Trait Genetics Eric Weine, Samuel Pattillo Smith ... Arbel Harpak GENETICS AND GENOMICS, EPIDEMIOLOGY AND GLOBAL HEALTH Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry Wei Q Deng, Nathan Cawte ... Sonia S Anand NEUROSCIENCE Decoding the Cognitive map: Learning place cells and remapping Markus Borud Pettersen, Vemund Sigmundson Schøyen ... Mikkel Elle Lepperød NEUROSCIENCE Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure Stefan Passlick, Ghanim Ullah, Christian Henneberger NEUROSCIENCE Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models Ulrike Pech, Jasper Janssens ... Patrik Verstreken STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS Ligand-Coupled Conformational Changes in a Cyclic Nucleotide-Gated Ion Channel Revealed by Time-Resolved Transition Metal Ion FRET Pierce Eggan, Sharona E Gordon, William N Zagotta MICROBIOLOGY AND INFECTIOUS DISEASE SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle Alice L Herneisen, Michelle L Peters ... Sebastian Lourido BIOCHEMISTRY AND CHEMICAL BIOLOGY, STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery Viviane Kremling, Sven Falke ... Janina Sprenger DEVELOPMENTAL BIOLOGY Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women Emily Delgouffe, Samuel Madureira Silva ... Ellen Goossens COMPUTATIONAL AND SYSTEMS BIOLOGY Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis K Patel, MJ Barter ... DP Shanley MICROBIOLOGY AND INFECTIOUS DISEASE Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway Xin Ma, Li Meng ... Xinyan Han STRUCTURAL BIOLOGY AND MOLECULAR BIOPHYSICS Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ Jinsai Shang, Douglas J Kojetin NEUROSCIENCE Reproducible, data-driven characterization of sleep based on brain dynamics and transitions from whole-night fMRI Fan Nils Yang, Dante Picchioni ... Jeff H Duyn NEUROSCIENCE Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing NEUROSCIENCE Revealing unexpected complex encoding but simple decoding mechanisms in motor cortex via separating behaviorally relevant neural signals Yangang Li, Xinyun Zhu ... Yueming Wang MEDICINE Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis Sindre Lee-Ødegård, Marit Hjorth ... Kåre I Birkeland CHROMOSOMES AND GENE EXPRESSION The transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay M Kelbert, A Jordán-Pla ... M Choder PHYSICS OF LIVING SYSTEMS Female-dominated disciplines have lower evaluated research quality and funding success rates, for men and women Alex James, Franca Buelow ... Ann Brower NEUROSCIENCE Cell-type-specific fluorescent tagging of endogenous target proteins reveals synaptic enrichment and dynamic regulations of dopamine receptors Shun Hiramatsu, Kokoro Saito ... Hiromu Tanimoto NEUROSCIENCE A robust brain network for sustained attention from adolescence to adulthood that predicts later substance use Yihe Weng, Johann Kruschwitz ... IMAGEN Consortium NEUROSCIENCE Disparity in temporal and spatial relationships between resting-state electrophysiological and fMRI signals Wenyu Tu, Samuel R. Cramer, Nanyin Zhang CANCER BIOLOGY Sex differences in bile acid homeostasis and excretion underlie the disparity in liver cancer incidence between males and females Megan E Patton, Sherwin Kelekar ... Sayeepriyadarshini Anakk NEUROSCIENCE Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity Audrey T Medeiros, Scott J Gratz ... Kate M OConnor-Giles GENETICS AND GENOMICS, STEM CELLS AND REGENERATIVE MEDICINE Delivery of A Jagged1-PEG-MAL hydrogel with Pediatric Human Bone Cells Regenerates Critically-Sized Craniofacial Bone Defects Archana Kamalakar, Brendan Tobin ... Steven L Goudy CELL BIOLOGY Human receptive endometrial organoid for deciphering the implantation window Yu Zhang, Rusong Zhao ... Han Zhao IMMUNOLOGY AND INFLAMMATION, CANCER BIOLOGY Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers Sofia V Krasik, Ekaterina A Bryushkova ... Ekaterina O Serebrovskaya NEUROSCIENCE Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation Elizabeth C Marin, Billy J Morris ... Gregory SXE Jefferis PLANT BIOLOGY Xanthomonas citri subsp. citri type III effector PthA4 directs the dynamical expression of a putative citrus carbohydrate-binding protein gene for canker formation Xinyu Chen, Huasong Zou ... Xiaojing Fan ECOLOGY Food-washing monkeys recognize the law of diminishing returns Jessica E. Rosien, Luke D. Fannin ... Amanda Tan BIOCHEMISTRY AND CHEMICAL BIOLOGY Probing PAC1 receptor activation across species with an engineered sensor Reto B Cola, Salome N Niethammer ... Tommaso Patriarchi CELL BIOLOGY, NEUROSCIENCE ATUM-Tomo: A multi-scale approach to cellular ultrastructure by combined volume scanning electron microscopy and electron tomography Georg Kislinger, Gunar Fabig ... Martina Schifferer PHYSICS OF LIVING SYSTEMS Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws M Julia Maristany, Anne Aguirre Gonzalez ... Jerelle A Joseph MEDICINE A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria