This special issue aims to address key areas in organoid research, including, but not limited to:
| • | Assembloids: Combining different organoid models to investigate multi-tissue interactions or complex neural circuits. |
| • | Cancer: Patient- and lab-derived tumor organoid models for biobanking, drug screening, co-culture, and translational applications. |
| • | Development: Embryoids, gastruloids, and 3D-tissue models for studies of early mammalian development. |
| • | Immunology: Immune-related and immune-integrated organoid models. |
| • | Neural development and disease: Neural organoids of the central and peripheral nervous system and retinal organoids, modeling development and neurodegenerative disorders. |
| • | Reproductive biology: Endometrial, placental, testicular, and ovarian organoids, for studies of fertility, pregnancy, and disease. |
| • | Tissue research and cellular heterogeneity: Modeling tissue microenvironments, extracellular matrix, and mechanobiology. |
| • | Tools: Applications using defined hydrogels and biomaterials, bioprinting, and microfluidic organ-on-chip platforms; analysis via live imaging, spatial-omics workflows, single-cell and multi-omics integration, and high-throughput perturbation screens. |