TOMORROW - PQG Working Group - Rany Salem
Andelman, Shaina B
TOMORROW, Tuesday, April 21, 2015
Building 2, Room 426 - Biostatistics Conference Room
12:30-2:00 PM
a pizza lunch will be served
Complex Trait Genetics: GWAS, Phenotypic Heterogeneity and Future Directions
The emergence of Genome-wide association studies (GWAS) has given researchers a powerful tool to dissect the genetic architecture of many complex traits. A major challenge of performing a GWAS is phenotype selection, and dealing with phenotypic heterogeneity. The first part of the talk will focus on results of the first large scale GWAS of diabetic kidney disease and issues related to identifying and dealing with phenotypic heterogeneity. For the second part of the talk, I will present a framework to deal with the limitations of the GWAS consortium model and briefly explore statistical and methodological issues to take advantage of this opportunity. Finally, I will highlight results of a novel association between a structural variant and lipid levels.
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2015 PQG Working Group Schedule
Tuesday, May 12, 2015
12:30-2:00 PM
Building 2, Room 426 - Biostatistics Conference Room
Jae-Hoon Sul, Sunyaev Lab at Brigham & Women's Hospital
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For more information on this series, and other PQG related events, please visit: www.hsph.harvard.edu/pqg