Project: Molecular dynamics study of gold-based biointerfaces for the development of nanomaterials with applications as biosensors, antimicrobial devices, magnetic and photothermal therapies, and bioimaging
We offer a research project on the characterization of gold biointerfaces using electrochemical techniques such as cyclic voltammetry and chronoamperometry, among others. Benzimidazoles are an emerging class of organic ligands at gold nanoparticles with promising properties suited for potential applications in corrosion science, biosensing and lithographic patterning. The results of this work will provide unprecedented insights into layer structure and function that will be leveraged for better biosensor designs in future work [Charchar,2016]. The project will use electrical measurements of various benzimidazole layers on gold to understand the organization of the resulting interfaces and the hysteresis in current vs voltage measurements. These measurements will be correlated with molecular dynamics simulations to better understand the organizational effect of these ligands on the electrochemistry of gold surfaces. The interested candidate must apply for the Masters or PhD programs of the Posgrado en Ciencias Biologicas (UNAM; https://pcbiol.posgrado.unam.mx/convocatorias.html). Experience in conducting research projects with an interdisciplinary perspective is advised. Background in chemistry, electrochemistry, biochemistry, physics, and/or physical-chemistry; experience as linux user, and programing skills are very welcome.
References
1. Understanding and Designing the Gold–Bio Interface: Insights from Simulations
Patrick Charchar, Andrew J. Christofferson, Nevena Todorova, and Irene Yarovsky. small 2016, 12, No. 18, 2395–2418.
More Information.
Eduardo Jardon
h.ja...@correo.ler.uam.mx (Recursos de la Tierra UAM-LERMA)
Netzahualcoyotl Arroyo ( Pharmacology and Molecular Sciences
Johns Hopkins University School of Medicine)
netza...@jhmi.edu