categorical variable
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Troels
Jun 8, 2009, 5:15:48 AM6/8/09
to BIMBAM HELP
Dear all,
I would like to explore 6 SNPs in one gene vs. a categorical variable,
but assuming a trend across the categories. The categories are
toxicity grades eg. neuropathy grade 0-3. Would it be wrong to just
use the tox scores as "quantitative" variable in BIMBAM ? I have
approximately 100 patients with approximately 25 in each of score 0 to
3. If not, I guess the alternative would be to dikotomize as in case/
control approach.
your thoughts will be appreciated,
best regards,
Troels, University of Southern Denmark
I would like to explore 6 SNPs in one gene vs. a categorical variable,
but assuming a trend across the categories. The categories are
toxicity grades eg. neuropathy grade 0-3. Would it be wrong to just
use the tox scores as "quantitative" variable in BIMBAM ? I have
approximately 100 patients with approximately 25 in each of score 0 to
3. If not, I guess the alternative would be to dikotomize as in case/
control approach.
your thoughts will be appreciated,
best regards,
Troels, University of Southern Denmark
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