Lack of sleep hinders coping skills, logical reasoning: study*
(CBC) - Scientists have confirmed what every newborn-cradling,
sleep-deprived parent knows: that lack of sleep is connected to an
inability to cope with normal emotional challenges.
They also theorize that sleep deprivation is linked to psychiatric
ailments such as anxiety, depression and bipolar disorder.
Scientists at the University of California at Berkeley and Harvard
Medical School have found that the amygdala, the region of the brain
that alerts the body to protect itself in times of danger, goes into
overdrive on no sleep. This in turn shuts down the prefrontal cortex,
which commands logical reasoning, and thus prevents the release of
chemicals needed to calm down the fight-or-flight reflex.
The findings are published Oct. 22 in the journal Current Biology.
"It's almost as though, without sleep, the brain had reverted back to
more primitive patterns of activity, in that it was unable to put
emotional experiences into context and produce controlled, appropriate
responses," said Matthew Walker, director of UC Berkeley's Sleep and
Neuroimaging Laboratory and senior author of the study, in a release.
The researchers studied 26 healthy participants aged 18 to 30, splitting
them into two groups with equal numbers of males and females.
The sleep-deprived group stayed awake during Day 1, Night 1 and Day 2,
while the sleep-control group stayed awake both days and slept normally
during the night.
The participants' brains were scanned with magnetic resonance imaging
while they were exposed to images that ranged from neutral to very
negative. The brain responses of the participants were measured.
Researchers found that the amygdala became hyperactive in response to
negative visual stimuli such as mutilated bodies, children with tumors
and other gory images in study participants who stayed awake for 35
hours straight.
Brain scans of those who got a full night's sleep in their own beds
showed normal activity in the amygdala.
"The emotional centres of the brain were over 60 per cent more reactive
under conditions of sleep deprivation than in subjects who had obtained
a normal night of sleep," Walker said.
The researchers feel that the findings point to a connection between
sleep disruption and mood disorders, including bipolar disorder.