And a link to the abstract at PNAS: http://www.pnas.org/content/early/2010/03/08/0913635107.abstract
Here's a bit from the press release: “This shows that computational
analysis of existing data can provide clues about where researchers
should look next,” he said. “This is something that could have an
impact on cancer. It’s exciting.”
And from the abstract: "These data demonstrate the power of MiDReG in
predicting functionally important intermediate genes in a given
developmental pathway that is defined by a mutually exclusive gene
expression pattern."
I would like to see more work like this, I think it's an excellent
example of finding valuable novel information in data that had been
mined extensively previously, and doing it quickly. I also like the
fact that the paper is open access, nice!