Error when I run beast

[Harry Sindle]

Hello,

It's my first time using BEAST, I'm getting an error when I run my .xml file generated through BEAUti 2. I've changed the seed, but get the same error - can anyone help at all? Thanks!

    
Running file /Users/harrysindle/Library/Mobile Documents/com~apple~CloudDocs/Biochemistry/Yr 3/Diss/Genetic Data/final/New-Final + Mosq/DNA - Own Data : All/DNA_Data.xml
File: DNA_Data.xml seed: 2763197384238588017 threads: 1
Loading package SSM v1.2.0 starbeast3 v1.1.8 SA v2.1.1 BEAST.base v2.7.6 BEASTLabs v2.0.2 BEAST.app v2.7.6 ORC v1.2.0    
Alignment(DNA_Aligned_MUSCLE)
  61 taxa
  12683 sites
  3773 patterns

Starting frequencies: [0.25, 0.25, 0.25, 0.25]
Failed to load BEAGLE library: no hmsbeagle-jni in java.library.path: $JAVAROOT:/usr/local/lib
TreeLikelihood(treeLikelihood.DNA_Aligned_MUSCLE0) uses BeerLikelihoodCore4
  Alignment(DNA_Aligned_MUSCLE): [taxa, patterns, sites] = [61, 3773, 12683]
Warning: removing transform class beast.base.inference.operator.kernel.Transform$LogConstrainedSumTransform because it should have at least 2 dimensions but it has 0
===============================================================================
Citations for this model:

Bouckaert, Remco, Timothy G. Vaughan, Joￃﾫlle Barido-Sottani, Sebastiￃﾡn Duchￃﾪne, Mathieu Fourment,
Alexandra Gavryushkina, Joseph Heled, Graham Jones, Denise Kￃﾼhnert, Nicola De Maio, Michael Matschiner,
Fￃﾡbio K. Mendes, Nicola F. Mￃﾼller, Huw A. Ogilvie, Louis du Plessis, Alex Popinga, Andrew Rambaut,
David Rasmussen, Igor Siveroni, Marc A. Suchard, Chieh-Hsi Wu, Dong Xie, Chi Zhang, Tanja Stadler,
Alexei J. Drummond
  BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis.
  PLoS computational biology 15, no. 4 (2019): e1006650.

Drummond AJ, Suchard MA (2010) Bayesian random local clocks, or one rate to rule them all. BMC biology 8, 114.

Douglas J, Zhang R, Bouckaert R. Adaptive dating and fast proposals: Revisiting the phylogenetic relaxed clock model. PLoS computational biology. 2021 Feb 2;17(2):e1008322.

Bouckaert RR. An efficient coalescent epoch model for Bayesian phylogenetic inference. Systematic Biology, syac015, 2022

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Start likelihood: -Infinity after 10 initialisation attempts
P(posterior) = -Infinity (was -Infinity)
P(prior) = -Infinity (was -Infinity)
P(YuleModel.t:DNA_Aligned_MUSCLE) = -8.732461488873113 (was -8.732461488873113)
P(RRateChangesPrior.c:DNA_Aligned_MUSCLE) = -0.6931471805599453 (was -0.6931471805599453)
P(YuleBirthRatePrior.t:DNA_Aligned_MUSCLE) = -6.915086640662835 (was -6.915086640662835)
P(RRatesPrior.c:sDNA_Aligned_MUSCLE) = -829.8103968795389 (was -829.8103968795389)
P(GammaShapePrior.s:DNA_Aligned_MUSCLE) = -1.0 (was -1.0)
P(nVit_Chalc.prior) = -Infinity (was -Infinity)
P(likelihood) = NaN (was NaN)  **
P(treeLikelihood.DNA_Aligned_MUSCLE) = NaN (was NaN)  **
java.lang.RuntimeException: Could not find a proper state to initialise. Perhaps try another seed.
See http://www.beast2.org/2018/07/04/fatal-errors.html for other possible solutions.
at beast.base.inference.MCMC.run(Unknown Source)
at beastfx.app.beast.BeastMCMC.run(Unknown Source)
at beastfx.app.beast.Controller$2.run(Unknown Source)