How to estimate tMRCA

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MKPUMA NICODEMUS

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Jul 25, 2025, 4:37:28 PMJul 25
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Dear all,

I’ve run a BEAST analysis including five different datasets representing distinct clades of viruses sampled in a different countries, some of which were collected in different time periods. My challenge now is how I can estimate tMRCA with the beast mcmc.

Thank you 
Nicodemus 

Gaspary Eugene

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Jul 26, 2025, 1:00:38 AMJul 26
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Dear Nicodemus?,
BEAST does estimate tMRCA for each clade

First make sure you have sufficient temporal signal tested using TempEST....to avoid uncertainty in time-calibration

Second you could treat the clades as separate taxa during beauti set up 

Run  BEAST simultaneously for your taxa

All values will be estimated after the run ....you can see values using Tracer 

Good luck!!

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MKPUMA NICODEMUS

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Jul 26, 2025, 5:10:41 PMJul 26
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I have done all these, but where can go to in tracer recreate something similar to the attached picture.



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