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How to Remove Thumb.db file Hello Friends, Today Let us see how to remove Thumb.db. Thumb.db is a cache of the current picture in that directory to remove it go for following Step1 >> open "WINDOWS EXPLORER". Step2 >> go to "TOOLS". Step3 >> open "FOLDER OPTIONS". Step4 >> go to "VIEW". Step5 >> see 1st section "FILES & FOLDERS". Step6 >> click on the "DO NOT CACHE THUMBNAILS". now the thumbnail file will be removed from your computer once u do this the file will be never created.