The cryoplatform and compressor for the 1H/13C optimized cryoprobe have
been delivered. We are still waiting for delivery of the cryoprobe
itself. Once it arrives, we will have to make time for the
installation, but until then, we can keep running.
The cryoprobe will allow us to record carbon-detected experiments. A
few references to these types of experiments are included below for
proteins. It would also be interesting to see how these experiments
can be used for work with nucleic acids.
Jeff
Serber et al. JACS 122, 3554-3555.
New carbon-detected protein NMR experiments using a cryoprobe.
Bertini et al. Angew Chem Int Ed. 43, 2257-2259.
A heteronuclear direct-detection NMR spectroscopy experiment for
protein-backbone assignment.
Eletsk et al. J. Biomol NMR 26, 167-179.
A novel strategy for the assignment of side-chain resonances in
completely deuteriated large proteins using 13C spectroscopy.
http://www.cchem.berkeley.edu/wemmer/BayArea900/BayArea900.html