Hi Vibhor!
The release 15.0.1 was really great, if you can use it yet ... why not!? 😉
The vacuum operation should be executed as a regular maintenance task for Postgresql databases, mainly the ones that are growing a lot.
You can log into your database server as root and run a "su - postgres" to execute it as postgres user, also is good to stop writing into database during the process because it will build some locks when running (stop your AWX services in a maintenance window is the best way I can recommend).
So you can use the wrapper "vaccumdb -a" for all databases  or "vacuumdb -d awx" for just run into the right AWX database (supposing your AWX database is named "awx", you can check running the "psql -l" command as postgres user). See
here the info about the wrapper vacuumdb.
Hope it helps you!
All the best!