Corpus Callosum

[Naeim Bahrami]

Hi Jason, 

These 20 tracts are covering  the whole WM brain, pretty comprehensively. But would it be possible to extract the fibers existing and/or passing through other regions of Corpus Callosum including splenium, genu, and body of Corpus Callosum as well as forceps minors/majors?

It is possible that we draw an ROI for those regions and analyze the fibers inside those ROIs but is there any designated fiber bundle(s) representing the whole Corpus Callosum?

Regards,

Naeim Bahrami

[Jason Yeatman]

See AFQ_SegmentCallosum

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[Ted Turesky]

Hi Jason et al.,

Foremost, thank you for both the incredibly helpful tool (AFQ) and the continued support for it. I was trying to capture tractography from more of the corpus callosum, so used the AFQ_SegmentCallosum function. But I had a couple questions about it:

1. at the top, there's a note that the script is still being developed. Is this still a concern?

2. I noticed that the occipital segment reconstruction (from AFQ_Segment Callosum) was a bit different from the corpus callosum major reconstruction and that their respective ROI waypoints were in slightly different locations. My understanding is that the ROIs for the corpus callosum major come from the JHU templates, but would it be possible to know more about the ROIs used by AFQ_SegmentCallosum? I'm trying to figure out which might be better to use...

Thank you!

Ted

[Jason Yeatman]

Hi Ted,

That function was developed and used for this paper:

• Yeatman J.D., Wandell B.A., Mezer A. (2014). Lifespan Maturation and Degeneration of Human Brain White matter. Nature Communications. 5:4932. PDF

The ROIs were based on this paper:

https://www-pnas-org.stanford.idm.oclc.org/content/104/20/8556

I think the function works fine. But maybe not as fully vetted as other aspects of AFQ.

The difference in ROIs is whether you want the occipital and posterior parietal segments split.

To view this discussion on the web visit https://groups.google.com/d/msgid/automated-fiber-quantification-afq/66e0c94e-2827-48ce-a3f2-c8a57244ffc3n%40googlegroups.com.

[Ted Turesky]

This is *super* helpful, Jason. Thank you! Any chance you could resend the PNAS link again though? I'm getting prompted for a Stanford login when I click on it.

[Jason Yeatman]

Dougherty, R. F., Michal Ben-Shachar, Gayle K. Deutsch, Arvel Hernandez, Glenn R. Fox, and B. A. Wandell. 2007. “Temporal-Callosal Pathway Diffusivity Predicts Phonological Skills in Children.” Proceedings of the National Academy of Sciences of the United States of America 104 (20): 8556–61.

To view this discussion on the web visit https://groups.google.com/d/msgid/automated-fiber-quantification-afq/73ab7d13-4add-4a7e-984f-c0428ba730e5n%40googlegroups.com.

[Ted Turesky]

Thank you, Jason!!