pCASL 1st & 2nd level analysis

[Ekaterina Lunkova]

Dear Dr. Wang,

I am a PhD student and currently I'm working on processing of ASL data for healthy controls and concussed subjects. I successfully obtained CBF maps for each individual, and I'd like to do a group analysis. The data I'm processing is pCASL in resting condition (no task) and I tried starting 1st level analysis wth batch_model.m. I have a few questions:

1) What should I input as PAR.condnum and PAR.cond_names as well as for onset times, as it's a resting state and I assume the condition is only one? 

2) What is the input image for this script? The CBF map for each subject (meanCBF_0_asl.img)?

Thank you very much in advance!

Best regards,

Ekaterina Lunkova

[tianci_369358727]

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[Ze Wang]

HI Ekaterina,

    If you are comparing mean CBF across two populations, you can calculate the mean CBF maps, then register them to MNI space and run a two-sample t-test.  You can take a look at the example data with customized code in 

https://somumaryland-my.sharepoint.com/:f:/g/personal/ze_wang_som_umaryland_edu/EuMRw4t_D_FEjN91um9h5ZABjTG0t0lmRNTFwJ8D_gXs_Q?e=hW7M4U

Ze

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[tianci_369358727]

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