Variant sequences - basic Q

[Daniel Barker]

Hi Code Monkeys,

 

Is there an easy way to find a variant protein or coding sequence in the databases, e.g. human F508del-CFTR?

 

I can find the reference sequence in many places and indeed it has F in position 508. I can also find the reference sequence annotated with variations.

 

So it is possible to derive the variant sequence. But for some educational work, it would be great to get straight to FASTA-format protein and/or coding sequence for a range of variants. I am sure there will be a way – surely F508del-CFTR has many sequences in GenPept and GenBank, for example? What kind of query will get me there?

 

Thank you,

Daniel

 

Dr Daniel Barker

https://www.ed.ac.uk/profile/daniel-barker

 

The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336. Is e buidheann carthannais a th’ ann an Oilthigh Dhùn Èideann, clàraichte an Alba, àireamh clàraidh SC005336.