I use KISS
Two parts to this, a cronjob which sets the radio to KISS, and which I
run from cron @reboot in case of a complete power failure
and this interface section
#put radio in KISS mode and start aprx
@reboot /usr/local/bin/tmd710_tnc_setup && /sbin/aprx
<interface>
serial-device /dev/ttyUSB0 9600 8n1 KISS
callsign $mycall # callsign defaults to $mycall
tx-ok true # transmitter enable defaults to false
</interface>
you will have to compile the code for your processor - mine is
"Feroceon 88FR131 rev 1 (v5l)" in a liberated Pogoplug