Cypher Setup Fracture

[Fernando Capelle]

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Repetitive mechanical forces within the coronary artery may result in stent fracture after stent implantation, particularly in patients with complex coronary disease. This study sought to estimate the incidence of Cypher stent fracture in patients with moderately severe coronary disease and to identify the angiographic predictors of fractures in patients identified in a global Cypher fracture registry. Stent fracture analysis was performed in 305 patients treated with the Cypher stent in SIRIUS and in 39 patients with stent fractures reported in the Cypher fracture registry. Fractures were classified as isolated strut fractures (type 1, single-strut fracture; type 2, incomplete transverse fracture) and stent fracture (type 3, complete transverse fracture without displacement; type 4, transverse fracture with displacement). Isolated strut fractures were identified in 4 patients (1.3%) enrolled in SIRIUS (type 1 1.0%, type 2 0.3%); no stent fractures were identified. In 39 patients with 44 clinically reported Cypher fractures, isolated strut fractures were present in 15.4% (all type 2) and stent fractures were found in 84.6% (type 3 38.4%, type 4 46.2%). Compared with patients in SIRIUS, patients with clinically reported fractures had much greater lesion complexity, including extensive calcification, angulation > or =45 degrees , lesion length > or =20 mm, proximal vessel tortuosity, total occlusions, and an ostial location. Clinically reported fractures were associated with a high rate of repeat target lesion revascularization (52.6%). In conclusion, stent fracture after Cypher stent placement occurs more often in patients with "ultra"-complex coronary anatomy, but is an uncommon event in patients treated with mild to moderate lesion complexity.

ngl i have seen a lot of KJs on Fracture just farming ult orbs and doing that Under B site tunnel ult for retakes or just taking control of the site while on attack. that does help the team a lot.
But I also chose cypher because there are so many object/boxes/ridges around the map that you can put tripwires for almost anything.
and imo double sentinel on fracture is good? because each site has 2 entrances and its hard for one sentinel to support everyone.

5th slot can be anything. It is interesting. You could potentially run a cypher, raze isn't bad, you could even run something like KAY/0 and make it work. You could even do double smokes and do some cool stuff. The 5th slot is really up in the air.

Background: Coronary stent fracture is an underrecognized entity but has been reported more frequently in the drug-eluting stent (DES) era. Nevertheless, the clinical implications of coronary stent fracture remain unclear.

Methods and materials: A literature search for reports of DES fracture was conducted via MEDLINE, and the US Food and Drug Administration Manufacturer and User facility Device Experience (MAUDE) database was accessed via the internet and interrogated for reports of stent fracture between January 1, 2003, and April 30, 2008. Each report was reviewed, and clinical information was extracted for analysis.

Results: The MEDLINE search identified 202 cases of coronary DES fracture, with 95% of cases involving Cypher sirolimus-eluting stents. Clinical information regarding patient presentation was available in 96 cases. Patients presented with ST-elevation myocardial infarction (STEMI) or stent thrombosis in six cases (6%) and with unstable angina or non-STEMI (NSTEMI) in 40 cases (42%). The MAUDE database search identified 337 stent fracture reports, with 97% of cases involving Cypher stents. Clinical information regarding patient presentation was available 193 cases. Patients presented with STEMI or stent thrombosis in 24 cases (12%) and with unstable angina or NSTEMI in 36 cases (19%).

Conclusions: Most reports of drug-eluting stent fracture involve Cypher stents. DES fracture can be associated with stent thrombosis, myocardial infarction and angina. However, whether the incidence of such events reported in the literature and in the MAUDE database is representative of all patients experiencing stent fracture remains unclear.

Fracture is one of the ten maps in VALORANT. It is set in a Kingdom facility in α-Earth. The map is designed for unique gameplay, to facilitate the Attackers pinching sites from both the front and back ends.

Fracture is a map set in an abandoned Kingdom research facility (located near Diablo Canyon, New Mexico), named the 'Everett-Linde Facility'. It was the site of development of a Radian Collider, meant for advanced study of Radianite particles. Uniquely, the activities that took place here were done through cooperation of the Kingdoms of both α-Earth and Ω-Earth.

To avoid confusion between the two Kingdoms, they are referred to by unique names: the Kingdom of α-Earth refer to themselves as Kingdom Corp (or K-CORP), and the Kingdom of Ω-Earth refer to themselves as Kingdom Industries (or K-IND).

Due to an event orchestrated by α-Chamber and Ω-Chamber (known as the 'Everett-Linde Disaster' or the 'Everett-Linde Incident'), the Radian Collider was blown up, destroying the facility and killing most (if not all) of the scientists working there. Due to the disaster, the facility remains in a dilapidated, abandoned state to this day.

The most prominent effect caused by the Disaster was the Dual-Biome Split[1], punctuated by a massive blue fracture between the two halves of the facility (it is from this Fracture that the map gets its name).

When working on Fracture's lore, the Devs intended to work by systems other than the usual mix of 'vague environmental storytelling coupled with the occasional voicelines and a Playercard'[2]. Because of this, a lot of the lore for this map has been conveyed through periodically updating interactables, cryptic cyphers and, and other such elements. An archive of all these has been made by Kingdom Archives.

The updates to the story were added in a chronological manner in the bimonthly patches. These updates include new visuals in various terminal screens, new emails, and new messages spoken by an announcer. At the top right of the emails, the date when they were sent is also present, which provides us some idea of the timeframe in which the events occurred.

Since the Devs have historically refrained from using concrete dates anywhere[3][4], an unconventional dating system was developed. Days are numbered in reference to a certain 'epoch event' in the near future, which would take place at day 0.

Instead of showing a standard Gregorian date, the dates shown on the emails use a T-minus countdown format to the day of the epoch event, with the number counting down the number of days left until the event (for example, 'T-100' means that there are 100 days left until that event occurs; 'T-365' means that there are 365 days left until that event occurs). As the emails were released in chronological order starting over a year before the epoch event, time moves forward as the numbers either remain the same or go down with each new email added, with the final emails arriving on the day of the event, denoted as T-0.

It was later shown that this 'Epoch Event' would be the first time that the Large Radian Collider (the LRC) would first become fully functional and active. Sadly, since the Chambers decided that T-0 day would also be the day that the Radian Collider was to be destroyed, the dating system is also a counter of how many days most of the scientists have left to live.

The earliest email present in the patch when Fracture was released (Patch 3.05) was dated 'T-482'. This is the time from where the story, as it is narrated in game, begins. We meet the two main characters, who are the ones sending and receiving most of the Fracture Emails: Oran McEneff (of K-CORP) and Rben Pontes (of K-IND). They are engineers working together on the development of the LRC.

We also get an insight into the working of the Facility. While it is certainly a cooperative effort between both the Kingdoms, there is still plenty of visible distrust between the two. Employees are discouraged from fraternizing with those of the other Earth, and simultaneous shifts with one's Mirrorverse counterpart are strictly prohibited.

This is furthered by a series of posters and printings found along the walls of the map, which encourage employees to keep any important information away from the other Kingdom. The level of teamwork seen between Oran and Rben is unheard of anywhere else in the facility.

Paul Delmann (the Employee of the Year at Icebox) is also set to move into Everett-Linde at around this time. One of the announcer messages says that Paul is awaiting a Shipment from Icebox. Later, in a Dev AmA session on Reddit, it was announced that this was in wake of Paul's office transfer from Icebox to Everett-Linde[5]. Paul's security card can also be found as an interactable, buried in the sand near Attacker Bridge.

The work that is being done at Everett-Linde was very important, yet is also a great secret. Almost everyone (in both the worlds) is completely unaware of even the existence of the Lab. Sadly, even we are given precious little information about what exactly the work done here is.

While several glimpses are given in the emails as to the relevance of said work (such as Rben telling Oran that what they do is to help "build worlds worth living in", and Aurora (Rben's Niece) describing it as "top secret saving-the-world blah blah blah whatever"), rarely is any specific information given.

From the nature of the Radian Collider, we can assume that it has to do with advanced physics and the study of Radianite. Killjoy's voicemail to Brimstone states that some of the research being done was related to "radianite exposure" and "biome acceleration". Judging from the wording used in Aurora's email, it is likely that whatever is being done here is of a paramount importance to the survival of one or both the the Earths. One possible goal could be to develop an alternate energy source for Ω-Earth, in wake of their Radianite shortage (this is, however, speculation, it is not canon)

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