MaxQuant crashing Thread?

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Jared Churko

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Feb 29, 2020, 1:00:38 PM2/29/20
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Hello, 

Any idea why MaxQuant crashes halfway though with this error?

Correcting errors 
Reading search engine results 
Preparing reverse hits 
Finish search engine results 
Filter identifications (MS/MS) 
Applying FDR 

Unhandled Exception:
System.Exception: Exception during execution of external process: 24887
  at BaseLibS.Util.WorkDispatcher.ProcessSingleRunExternalProcess (System.Int32 taskIndex, System.Int32 threadIndex) [0x001a1] in <3fc1eb7cc45041de8ce7f41aa00f3311>:0 
  at BaseLibS.Util.WorkDispatcher.DoWork (System.Int32 taskIndex, System.Int32 threadIndex) [0x0001e] in <3fc1eb7cc45041de8ce7f41aa00f3311>:0 
  at BaseLibS.Util.WorkDispatcher.Work (System.Object threadIndex) [0x00054] in <3fc1eb7cc45041de8ce7f41aa00f3311>:0 
  at System.Threading.ThreadHelper.ThreadStart_Context (System.Object state) <0x7f22daeadd70 + 0x00089> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ExecutionContext.RunInternal (System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, System.Object state, System.Boolean preserveSyncCtx) <0x7f22daeab7a0 + 0x00147> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ExecutionContext.Run (System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, System.Object state, System.Boolean preserveSyncCtx) <0x7f22daeab720 + 0x00022> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ExecutionContext.Run (System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, System.Object state) <0x7f22daeab6a0 + 0x00034> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ThreadHelper.ThreadStart (System.Object obj) <0x7f22daeade50 + 0x0004d> in <a1ae6166591d4020b810288d19af38d4>:0 
[ERROR] FATAL UNHANDLED EXCEPTION: System.Exception: Exception during execution of external process: 24887
  at BaseLibS.Util.WorkDispatcher.ProcessSingleRunExternalProcess (System.Int32 taskIndex, System.Int32 threadIndex) [0x001a1] in <3fc1eb7cc45041de8ce7f41aa00f3311>:0 
  at BaseLibS.Util.WorkDispatcher.DoWork (System.Int32 taskIndex, System.Int32 threadIndex) [0x0001e] in <3fc1eb7cc45041de8ce7f41aa00f3311>:0 
  at BaseLibS.Util.WorkDispatcher.Work (System.Object threadIndex) [0x00054] in <3fc1eb7cc45041de8ce7f41aa00f3311>:0 
  at System.Threading.ThreadHelper.ThreadStart_Context (System.Object state) <0x7f22daeadd70 + 0x00089> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ExecutionContext.RunInternal (System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, System.Object state, System.Boolean preserveSyncCtx) <0x7f22daeab7a0 + 0x00147> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ExecutionContext.Run (System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, System.Object state, System.Boolean preserveSyncCtx) <0x7f22daeab720 + 0x00022> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ExecutionContext.Run (System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, System.Object state) <0x7f22daeab6a0 + 0x00034> in <a1ae6166591d4020b810288d19af38d4>:0 
  at System.Threading.ThreadHelper.ThreadStart (System.Object obj) <0x7f22daeade50 + 0x0004d> in <a1ae6166591d4020b810288d19af38d4>:0 

I'm running it on Ubuntu 19.10 with Mono JIT compiler version 6.8.0.105 and using the latest MaxQuant version. I've assigned 60 threads with over 600 gig ram to the run. 

Nathaniel Jorgenson

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Jun 23, 2021, 3:57:05 AM6/23/21
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I am having the same issue, but it is only with certain files. Did you find any solution to the problem?

Johanna Krueger

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3:27 AM (2 hours ago) 3:27 AM
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To me it only seems to happen when I have a large database or a file that has many PSMs. It crashes most times at "Reading search engine results". I guess it is memory related?
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