MaxQuant SPS MS3 TMT Reporter Ion 0

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Maia Helterbrand

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May 6, 2026, 12:38:37 PMMay 6
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Hi all,

MaxQuant v2.7.5.0 is successfully identifying peptides from MS2 scans, but is failing to properly register TMT labels (TMT10plex) and/or associate the correct SPS-MS3 scans, which is causing the reporter ion intensities to appear as zero. I checked the raw data and the reporter ions are clearly present. Is there any resolution to this problem?

Best,
Maia


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