Yes. Though some apps like Skype don't manage audio focus correctly and will take audio focus but not relinquish the mic when another app steals audio focus from them permanently or temporarily. Because managing audio focus correctly is "optional" it means you cant be sure things will work correctly when used alongside other apps.
I believe this failure to implement audio focus correctly was done in Skype because of a bug in older versions of Android (fixed after 4.0.4), where calling AudioManager.SetMode() would make you loose audio focus to the system if you had it. So Skype, which also calls SetMode(), just ignores audio focus loss and keeps the mic open. As soon as one app does that it breaks the whole focus model.
My work-around for this was to add a watchdog to monitor the audio thread, where if I don't get an audio tick within some time frame (500msec when using 20msec blocks) I emit my own error and close things down. Its an imperfect solution but works for now.