Re: potential single or combination drug therapy for T
�Bluto
>x-no-archive: yes
>
>I'm able to take a high oral dose of generic ergoloid mesylates without
>any side effects, for cogntion.
>
>Susan
yippie-yeah-oh-kay-eh
>
>Clinical study of Ternelin (R) therapy and Ternelin (R) and Hydergine
>(R) therapy for tinnitus
>
>Practica Otologica (Japan) , 1995, 88/5 (645-656)
>
>Patients with tinnitus were treated with Ternelin (R) (tizanidine
>hydrochloride) alone or in combination with Hydergine (R)
>(dihydroergotoxine mesylate). The following results were obtained. 1)
>When overal improvement was assessed at the end of the dosing period,
>36% of the 136 patients who received Ternelin (R) and Hydergine (R) (the
>combined therapy group) showed moderate or marked improvement, while
>61.8% of the patients in this group showed slight, moderate or marked
>improvement. The combined therapy was rated as moderately or highly
>useful in 35.3% and slightly to highly useful in 61% of all cases. 2) Of
>the 24 patients who received Ternelin (R) alone (the solo therapy
>group), 25% showed moderate or marked improvement, and 66.7% showed
>slight, moderate or marked improvement. Solo therapy was rated as
>moderately or highly useful in 25% and slightly to highly useful in
>66.7%. 3) Of the 153 patients who received combined therapy (including
>17 patients who were only included in the safety assessment), 9
>developed adverse reactions (3 cases of drowsiness, and one each of
>orthostatic syncope, hypotonia, dizziness, gastric pain, constipation
>and oral thirst). None of the patients given Ternelin (R) alone showed
>any adverse reactions. 4) The percentage of cases showing marked or
>moderate improvement was higher in the combined therapy group than in
>the solo therapy group, although this difference was not significant. In
>the combined therapy group, the reduction in tinnitus peaked 2 to 4
>weeks after the start of treatment. In the solo therapy group, the
>number of patients responding to the drug increased gradually with time,
>and more time was needed to obtain maximal effects than that in the
>combined therapy group.
Josepi
"Susan" <su...@nothanks.org> wrote in message
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