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Hormones and hair reduction

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Jokestress

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Jan 16, 1999, 3:00:00 AM1/16/99
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Karen Ross asked about HRT/hirsutism medical articles. I know of none following
TSs, but there have been a few on genetic women with PCOS, tumors,
hypothyroidism, adrenal 21 hydroxylase deficiency, and idiopathic hirsutism.

If anyone would like an overview of testosterone metabolism in
androgen-receptive cells (DHT, 5 alpha reductase, etc.), I could do an overview
of the process.

The following is from an excellent overview of the hirsutism literature by
Toronto endocrinologist Ivy Fettes, MD.

The mainstays for hirsutism therapy are anti-androgens and electrolysis, and
for those who are obese, weight loss.

Antiandrogens used in hirsute women showed decreases in the Ferriman/Gallwey
hirsutism index in as little as 3 months, but usually did not appear until 6
months of antiandrogen therapy. Of the three most common antiandrogens:

1. Spironolactone (Aldactone) is the most common choice for genetic women, but
its results are more gradual than cyproterone acetate.

2. Clients on cyproterone acetate (Androcur) and electrolysis appear to have
the most marked and rapid clinical improvement. It tends to be stored in fatty
tissue and released more consistently.

3. Flutamide (Euflex) has been used, but has a shorter duration of action and
is given in larger doses more frequently than the others drugs listed.

Fettes also notes that obesity is associated with increased production of
androgens and decreased sex hormone binding capacity, resulting in more
biologically active testosterone. Circulating levels of androgens can be
reduced with weight loss.

If there's any interest in a list of medical articles, I can supply that, too.

Take care,
Andrea

----------
Consumer hair removal facts:
http://members.aol.com/jokestress/haircompare.html

Natasha Fassett

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Jan 16, 1999, 3:00:00 AM1/16/99
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Hi Jokestress .
Thank you for goig to all the trouble and hard work.
You are a fount of wisdom, precisely why I fear you may be right about
Lasers.
I noticed you didn't mention Proscar - Finesterid. Do you have any info an
it you could share with us ?
What Karen Ross has to say is true, and I have never disputed that .
I also believe what I said is true. Getting cleared first is definately the
way to go as she said, yet not everyone can do it that way.
Well whatever you can tell us about Proscar would be apreciated.
Thank you.
As soon as alittle more time has passed, I will fill out your questionare
about Laser treatment.
I have a need to wait a bit befor I do though. BFN

Jokestress

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Jan 16, 1999, 3:00:00 AM1/16/99
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Natasha writes:

>I noticed you didn't mention Proscar - Finesterid.
>Do you have any info an it you could share with us ?

Because finasteride (Proscar) was originally indicated for prostate conditions
and is newer than the others, there is not as much about hirsutism treated with
it. Hirsutism in males is not considered as bad as it is in females, so the
hair loss side effect probably got less attention, certainly less than
finasteride's effects on scalp hair growth. Anyone using Propecia, Proscar, or
generic finasteide care to read and report on the packaing information's
comments on hair loss?

While I am familiar with some information on hormonal treatment of hirsutism,
endocrinology is not my strong suit. In fact, since there is so much
information on hormones, I avoid redundant efforts and ignore the issue almost
entirely.

While hormonal changes are welcome, I think they tend to be overrated in terms
of visible physical results. Certainly as far as facial hair removal, they will
by no means serve as a substitute for electrolysis.

Amber Thompson

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Jan 16, 1999, 3:00:00 AM1/16/99
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Jokestress wrote:

> While hormonal changes are welcome, I think they tend to be overrated in terms
> of visible physical results. Certainly as far as facial hair removal, they will
> by no means serve as a substitute for electrolysis.

This is a URL for a drug identification site.

--
Amber Thompson
ICQ#5904742
http://homepages.together.net/~msfrost/tananda.html
(Please do not link to my site without permission.)

Kim Taylor

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Jan 18, 1999, 3:00:00 AM1/18/99
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I would not use the 5% minoxodil anyway. it says right on the package
that it may promote increased facial hair growth in women.

After a year on high doses of Spiro and Premarin, my hair is coming back
just fine, thank you. (please don't ask my dosages. for the protection
of others, I do not give out that info in an open forum like this one.)

By using 2% minoxodil solution for 3 months prior to hrt and 2 months
into hrt, I think I prevented additional loss.

Kim

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