Low Iron Diet Reduces Tumors
ironjustice
tumor promotion in murine skin.
Gayatri Bhasin, Kauser, H., Mohammad Athar
Department of Medical Elementology and Toxicology,
Faculty of Science, Hamdard University, 110 062 New Delhi, India.
Archives of Toxicology
Abstract:
Recently, we have shown that low iron state reduces benzoyl
peroxide-mediated tumor promotion in murine skin.
To further test the dependence of iron on skin tumor development,
we assessed the effect of a low iron diet on 12-O-tetradecanoyl
phorbol-13-acetate (TPA)-mediated tumor promotion in murine skin.
Female Swiss albino mice were fed on a low iron diet and initiated
with a single dose of 7,12-dimethylbenz[a]anthracene (DMBA, 40 µg
as 150 µl per mouse) and promoted with TPA (2.5 µg as 200 µl per
mouse, twice-weekly application for 20 weeks).
The appearance of the first papilloma and the number of tumors
(papillomas and carcinomas) per mouse were recorded weekly.
We observed a decrease in tumor incidence (papillomas and
carcinomas) and number of tumors per mouse in TPA-promoted mice
fed on low iron diet (0.23 mg Fe/kg diet) compared to normal mice fed
on balanced mouse chow (1.70 mg Fe/kg diet).
The total iron consumption per day by mice being fed on balanced
mouse chow was 340-400 µg Fe/kg body weight, and the total iron
consumption per day by mice being fed on low iron diet was 45-55
µg Fe/kg body weight.
The number of papillomas per mouse was 45% lower and the
conversion of papillomas to carcinomas was about 20% lower in mice
fed a low iron diet.
The tumor size was also smaller in mice being fed on low iron diet.
TPA treatment resulted in decreases in the activities of antioxidant
enzymes and depletion in the level of epidermal reduced glutathione
(GSH).
Feeding mice on low iron diet along with TPA treatment resulted in
~50-75% recovery of the depleted levels of GSH and antioxidant
enzymes.
In addition, TPA-mediated induction of biological markers of tumor
promotion, viz. ornithine decarboxylase activity and [3H]thymidine
incorporation into cutaneous DNA, was about 60% lower in TPA-treated
mice fed on low iron diet than in normal mice treated with TPA.
Cutaneous iron levels were also lower in mice fed on low iron diet
than
in mice fed on normal diet.
Histopathological sections of the skin portion adjoining tumors
showed
a lower degree of epidermal hyperplasia and lesser infiltration of
inflammatory cells in the dermis, and absence of hyperkeratosis in
mice
fed on low iron diet.
Thus, in this study we observe that the tumor promoting potential of
TPA
is reduced in mice fed on low iron diet, which is also accompanied by
lesser inflammatory changes in the skin of tumor-bearing mice fed on
low iron diet.
Publisher: Springer-Verlag
------------------
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
fer...@paris.com
tumor promotion in murine skin."
Wouldn't it just be better to avoid the acetate and not have the cancer
in the first place?
ironjustice
You were told to stay off my threads ..
Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated
tumor promotion in murine skin.
fer...@paris.com
Are you sure? Huffing can cause paranoia and delusion.
ironjustice
You ain't listening ..
Loons .. shteaters .. shteating loons .. shteating atheist loons ..
loon shteaters .. loon shteating atheists .. loon atheists .. are ..
not
allowd .. near .. me ..
aspi...@gas.com
at least. Another board member also had this and had subsequent
cravings for nail polish/remover. She sited iron deficiency as the
root problem. But was having trouble absorbing nutrients via
And:
Do you take iron? It really helps with the cravings. I was at a point
where I need the rubbing alcohol so badly, i couldnt leave home
without a bottle. I left a bottle in my car by accident on a hot
summer day and it almost exploded. god forbid if anything was to
happen. read my post *rubbing alcohol is ruining me* and see what
others have to say about their iron intake also. since ive been
taking
my iron regularly, i havent had the crave as much. ive been up for 4
hours now and havent went to the bottle or purell or anything. and it
feels good. ill crave later, as any addiction would do to you. but
its
easier to say no when your hgb and hct is at a good level.
ironjustice
Rusty the Spamming Dickwadd
Happy Oyster
wrote:
>On May 30, 1:58�pm, ferr...@paris.com wrote:snip <<
>
>
>You were told to stay off my threads ..
Interesting stuff...
--
DIE ERSTE REIMBIBEL SEIT DEM MITTELALTER
http://www.reimbibel.de
Happy Oyster
wrote:
>On May 30, 4:57�pm, ferr...@paris.com wrote:snip <<
>
>You ain't listening ..
>
>Loons .. shteaters .. shteating loons .. shteating atheist loons ..
>loon shteaters .. loon shteating atheists .. loon atheists .. are ..
>not
>allowd .. near .. me ..
Oh, dear me, the most prominent part is left out - for obvious reasons:
The Idiots in the Net
*********************
They push others in the graves, and they are proud of it.
Like the anti-vaxxers, who have not problem at all to deny other people the
right to live.
Interesting material about the religiotic background of the anti-vaxxers:
http://www.pharmamafia.com
http://www.pharmamafia.de
http://www.impfkritiker.de
http://wehrhafte.medizin.se
ironjustice
wrote:snip
<<
Stockdumm Zwitter Exkremente Esser
-------------------
Rusty the Spamming Dicksucker
Happy Oyster
wrote:
>On May 31, 7:26�am, Happy Oyster <happy.oys...@ariplex.com>
>wrote:snip
><<
>
>Stockdumm Zwitter Exkremente Esser
>Spamming the hell out of the boards??
There goes #5...
To point out the backgrund of those crazy attacks we should see the driving
forces, one of them being religious insanity.
I wasn't in the usenet for quite a long time. During this time naturopath
mafiosi like Jan Drew went on to pest the net with wrong claims, with
advertising for naturopath crap, with lying about vaccination, with lying about
useful medical treatments.
Now that I am back here just for a glimpse, the naturopath mafiosi are shocked.
The naturopath mafiosi cannot withstand clear facts. As they have no facts they
work by attacking persons with ad hominems, with stalking at their employers and
in their families and the neighborhood. And with lies, lies, lies.
All those pests in the net, may they have financial reasons or not, push others
in the graves, and they are proud of it.
Like the anti-vaxxers, who have no problem at all to deny other people the right
to live.
Interesting material about the religiotic background of the anti-vaxxers:
http://www.pharmamafia.com
http://www.pharmamafia.de
http://www.impfkritiker.de
http://wehrhafte.medizin.se
Some useful web-sites:
Laborjournal + Lab Times
http://www.laborjournal.de/
http://www.labtimes.org/
Science-based Medicine
http://www.sciencebasedmedicine.org/
Neurologica-Blog
http://www.theness.com/neurologicablog/
THE Rudolf-Steiner-Blog
http://rudolf-steiner.blogspot.com/
Orac's Lair:
http://www.orac.me
Respectful insolence
http://scienceblogs.com/insolence/
Eso-Blog
http://blog.esowatch.com/
Vereniging tegen de Kwakzalverij
http://www.kwakzalverij.nl/
Kritisch gedacht
http://www.scienceblogs.de/kritisch-gedacht/
The Skepdoc
http://www.skepdoc.info/
What's the harm?
http://www.whatstheharm.net
Skepsis Blog Norway
http://www.skepsis.no/blog/
Aetiology
http://scienceblogs.com/aetiology/
Just to name a few of those who publish rock-solid science-based medicine in the
net.
Aribert Deckers
http://www.deathsect.com
ironjustice
snip <<
You shteating disease ridden mutated homosexual atheists are
congregating ..
You shteating disease ridden mutated homosexual atheists were told you
are
not allowed to do that ..
It smells the place up you .. Stockdumm Zwitter Exkremente Esser
Rusty the Spamming Canuck Faggot
aspi...@gas.com
J
> What's the harm?
> http://www.whatstheharm.net
>
Here's another that can be added to the above website list
http://www.whatstheharm.net/alternativemedicine.html
http://www.venicehouserestaurants.com/ce/main.htm
http://www.venicehouserestaurants.com/clnmedia/index.htm
http://www.venicehouserestaurants.com/ce/summary-events.htm
25 Aug, 2004
Open letter to Ian Shillington, natoropathic doctor. Click here to read letter.
http://www.venicehouserestaurants.com/ce/diary-1aug04.htm
Hi Ian,
I am glad to hear from you since it gives me the opportunity to clean the house.
It surprises me that you would ask me how I am doing since you know I run an online
diary since October 2003.
I am going to open my mind with you to let you know how unlucky I feel in having met
you on my healing path.
Your "piece of cake" approach to serious cancer activity has fooled me in taking
wrong decisions. Don't worry, I know very well what you would say... the ultimate
decision lay in my hands. However this decision was made as a result of your
confidence that this was an easy matter using your program. While on the program
when I showed concern about the CEA rising. You said this was probably a good thing
as the body was getting rid of the cancer. You could not be any further away from
the truth.
I am not running away from my responsibility, but I can still point at your actions
and your irresponsible words to help someone else in my situation make better
decisions.
Your playing remote naturopathic doctor with serious cases and suggesting that you
have alternatives to surgery... is criminal. My tumor, operable in October 2003
resulted inoperable in March 2004 and I had no alternatives to the stoma since my
bowel was totally blocked. The stoma has taken away my quality of life as a
physically active person.
I am in palliative care now, I better spell this for you since you don't read the
diary. I had ample time to ponder on all has happened in the last few months and see
what I could have done differently.
You are a very bad example of what a N.D. can be. Your arrogance in thinking that
you are the only one to know what is right is inadmissible.
This is an open letter that will be added to my online diary to help other people to
beaware of charlatans that can have a profound effect on one's health.
Regards,
Stephen Serenelli.
Happy Oyster
>Happy Oyster wrote:
>
>> What's the harm?
>> http://www.whatstheharm.net
>>
>
>Here's another that can be added to the above website list
>http://www.whatstheharm.net/alternativemedicine.html
>
>
> http://www.venicehouserestaurants.com/ce/main.htm
>http://www.venicehouserestaurants.com/clnmedia/index.htm
>
Thank you. I will have a closer look at this.
Aribert Deckers
ironjustice
wrote:snip
<<
Stockdumm Zwitter Exkremente Essers ..
gemini-aquarius7
Visit the Greatest site for good health products.See these Affiliates
(Wonderlabs - Health Products)
(Cloudnine - Anti-aging Products) You may also visit Amazon.com
"ironjustice" <ironj...@cashette.com> wrote in message
news:e4e0f67c-9a85-47d0...@t10g2000vbg.googlegroups.com...
Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated
tumor promotion in murine skin.
Gayatri Bhasin, Kauser, H., Mohammad Athar
Department of Medical Elementology and Toxicology,
Faculty of Science, Hamdard University, 110 062 New Delhi, India.
Archives of Toxicology
Abstract:
Recently, we have shown that low iron state reduces benzoyl
peroxide-mediated tumor promotion in murine skin.
To further test the dependence of iron on skin tumor development,
we assessed the effect of a low iron diet on 12-O-tetradecanoyl
phorbol-13-acetate (TPA)-mediated tumor promotion in murine skin.
Female Swiss albino mice were fed on a low iron diet and initiated
with a single dose of 7,12-dimethylbenz[a]anthracene (DMBA, 40 �g
as 150 �l per mouse) and promoted with TPA (2.5 �g as 200 �l per
mouse, twice-weekly application for 20 weeks).
The appearance of the first papilloma and the number of tumors
(papillomas and carcinomas) per mouse were recorded weekly.
We observed a decrease in tumor incidence (papillomas and
carcinomas) and number of tumors per mouse in TPA-promoted mice
fed on low iron diet (0.23 mg Fe/kg diet) compared to normal mice fed
on balanced mouse chow (1.70 mg Fe/kg diet).
The total iron consumption per day by mice being fed on balanced
mouse chow was 340-400 �g Fe/kg body weight, and the total iron
consumption per day by mice being fed on low iron diet was 45-55
�g Fe/kg body weight.
gemini-aquarius7
Visit the Greatest site for good health products.See these Affiliates
(Wonderlabs - Health Products)
(Cloudnine - Anti-aging Products) You may also visit Amazon.com
<fer...@paris.com> wrote in message
news:4a219e0e$0$23842$1c46...@news.club.cc.cmu.edu...
ironjustice
<<
You stinking predatory .. shteaters ..
Giiiiiiit .. shteater ..
Giiiiiiiiit ..
Stockdumm Zwitter Exkremente Essers ..
-------------------
Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated
tumor promotion in murine skin.
Publisher: Springer-Verlag
------------------
Who loves ya.
Tom
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More options Jun 11, 12:54 pm
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From: "gemini-aquarius7" <a...@b.com>
Date: Thu, 11 Jun 2009 14:54:22 -0500
Local: Thurs, Jun 11 2009 12:54 pm
Subject: Re: Low Iron Diet Reduces Tumors
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www.gemini-aquarius7.com
Visit the Greatest site for good health products.See these Affiliates
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"ironjustice" <ironjust...@cashette.com> wrote in message
news:e4e0f67c-9a85-47d0-9b1a-
eeb77c...@t10g2000vbg.googlegroups.com...
Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated
tumor promotion in murine skin.
fer...@paris.com
> tumor promotion in murine skin."
Wouldn't it just be better to avoid the acetate and not have the
ironjustice
<<
You stinking predatory .. shteating .. looooon ..
Giiiiiiit .. shteater ..
Giiiiiiiiit ..
-------------------
Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated
tumor promotion in murine skin.
Publisher: Springer-Verlag
------------------
Who loves ya.
Tom
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More options Jun 11, 12:54 pm
Newsgroups: sci.med.nutrition, sci.med, misc.health.alternative,
alt.support.lupus, alt.support.cancer
From: "gemini-aquarius7" <a...@b.com>
Date: Thu, 11 Jun 2009 14:54:22 -0500
Local: Thurs, Jun 11 2009 12:54 pm
Subject: Re: Low Iron Diet Reduces Tumors
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"ironjustice" <ironjust...@cashette.com> wrote in message
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Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated
tumor promotion in murine skin.
gemini-aquarius7
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"Happy Oyster" <happy....@ariplex.com> wrote in message
news:ge45255evpu35r44e...@4ax.com...
ironjustice
<<
Giiiiiiit .. you stinking predatory .. shteating .. looooon ..
Giiiiiiiiit .. atheist ..
-------------------
Ken
Get out of your mom's basement, go into Rehab so you
won't be an eternal drain on the Canadian economy, but
don't come to the U.S. or you will have to register as a
sexual predator with a proven mental deficiency.
For your sake, and your mother's as well, you need to
get help with your copraphagic impulses. Let the neighbors
throw their kid's diapers away without having to see you
rummaging through their garbage bags. And your feces-
breath may be keeping those job interviews from being
productive.
Buy some mouthwash to get rid of your semen breath.
That's just gross
ironjustice
I .. TOLD you to .. dance .. while you post .. shteater ..
Do that little shteating .. predatorial .. atheist .. dance ..
Heh .. heh ..
Dance .. btch ..
Heh .. heh ..
Do a little .. dance .. while you .. doooo ..
To the tune ... of .. I'm a little teapot ..
"I'm a little .. athe-ist .. full .. of .. sht ..
This is my .. na-ture .. this is my .. snout"
Oink .. oink ..
Heh .. heh ..
Giiiiiiit .. you twisted fkg .. atheist .. shteater ..
Giiiiit .. atheist ..
ironjustice
ironjustice
The atheist .. shteating .. btch .. posts to my threads one more ..
time ..
Heh .. heh ..
Display that predatory nature .. common to .. you .. shteaters .. for
me ..
Ok .. atheist .. ?
Gooood ..
Place .. your predatory .. shteating atheist .. sht .. just below ..
Ok .. shteater ..?
Do a little .. dance .. while you .. doooo ..
To the tune ... of .. I'm a little teapot ..
"I'm a little .. athe-ist .. full .. of .. sht ..
This is my .. na-ture .. this is my .. snout"
Oink .. oink ..
Heh .. heh ..
Giiiiiiit .. you twisted fkg .. atheist .. shteater ..
Giiiiit .. atheist ..
------------------