Worth a punt for sure - Chronic Kidney Disease (CKD) Baking Soda slows kidney function decline

[Pendragon]

Chronic Kidney Disease (CKD)

- Baking Soda slows kidney function decline



? Bicarbonate also dramatically slows the rate of decline of
kidney function in patients with chronic kidney disease (CKD) -
Science Daily reported results from a randomised controlled trial
lasting 2 years involving 134 people with CKD and metabolic acidosis
at Royal London Hospital in England, that "in patients taking sodium
bicarbonate, the rate of decline in kidney function was similar to the
normal age-related decline" .



Metabolic acidosis

- “A condition where there is an acid-alkali imbalance in the
blood, that results in high blood acidity (low pH) and low plasma
bicarbonate levels. Several conditions can lead to metabolic acidosis,
including heart failure, drugs or toxins, kidney failure or diabetic
ketoacidosis (caused by high blood sugar resulting from reduced
insulin). It is a common complication in people with advanced chronic
kidney disease, and it can interfere with protein metabolism and may
lead to stunted growth (in children) and loss of bone and muscle.”

http://www.nhs.uk/news/2009/07July/Pages/Bakingsodaforkidneypatients.aspx





- People excluded from study - anyone with morbid obesity,
cognitive impairment, chronic sepsis, congestive heart failure or
uncontrolled blood pressure.



- Rate of creatinine clearance from kidneys was assessed -
Creatinine is a waste product usually removed by healthy kidneys and
is therefore a measure of kidney disease severity. Participants
provided 24-hour urine samples (collecting every drop of urine during
each period) every two months. Researchers defined rapid progression
as a reduction of creatinine clearance of more than three ml/min per
1.73m2 per year.



- Study results



v Those taking sodium bicarbonate supplements had
significantly higher blood bicarbonate levels



v Increased sodium levels in patients did NOT lead to any
problems with increased blood pressure



v Chronic kidney disease progressed rapidly in 9% of patients
in the bicarbonate group compared to 45% in the usual care group.



v Significantly fewer supplemented patients developed
end-stage renal failure (requiring dialysis) compared to the usual
care group - 6.5% versus 33% of patients.



v Supplementation was associated with better nutritional
status - including improved protein intake and more normal protein
metabolism.



Ione de Brito-Ashurst , Mira Varagunam , Martin J. Raftery , and
Muhammad M. Yaqoob. Bicarbonate Supplementation Slows Progression of
CKD and Improves Nutritional Status. Journal of the American Society
of Nephrology, 2009; DOI: 10.1681/ASN.2008111205





- Dose used to slow the rate of kidney decline in patients with
CKD



v Approx. 600 mg baking soda three times daily given orally
in tablet form (increased as necessary to achieve and maintain blood
levels) - 600 mg is equivalent to ~ ¼ TEAspoon baking soda powder,
which can be taken dissolved in a small glass of water or juice for
consumption





? For greatest effect in kidney disease, sodium bicarbonate
should always be used with magnesium chloride – providing a powerfully
synergistic therapy

[mainfr...@yahoo.com]

While the baking soda treatment is of sue in slowing the progression of CKD, the VLPD (Very Low Protein Diet) can often stop the progression altogether. That has ben my experience using that diet for eleven years now. Before that diet, I would have been in dialysis in 6-8 months!

Read "Coping with Kidney Disease" by Mackenzie Walser, MD.

Chris