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baking soda for early stage 3 patients

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col...@gmail.com

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Jun 30, 2019, 8:08:22 PM6/30/19
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More recently, a 5-year prospective, randomized, placebo-controlled blinded interventional study tested if daily oral sodium bicarbonate slowed GFR decline in patients with hypertensive nephropathy with reduced but relatively preserved estimated GFR (eGFR) (mean 75 ml/min per 1.73 m2). Participants matched for age, ethnicity, albuminuria, and eGFR received either daily placebo (n=40), equimolar sodium chloride (n=40), or sodium bicarbonate (n=40) while being maintained on their antihypertensive regimens (including angiotensin-converting enzyme [ACE] inhibition) treated to conventional BP targets. In keeping with their relatively preserved renal function, participants were not acidotic at enrollment with a mean total CO2 in ≥26 mmol/L. After 5 years, the rate of eGFR decline, estimated using plasma cystatin C, was slower and eGFR significantly higher in patients receiving sodium bicarbonate (baseline cysGFR [in ml/min per 1.73 m2], 73.2; after 5 years, 66.4) than in those given placebo (baseline, 73.5; after 5 years, 60.8) or sodium chloride (baseline, 73.5; after 5 years, 62.7). This interesting study calls for use of sodium bicarbonate in patients with early CKD even in the absence of overt acidosis (17).

hohum

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Jul 16, 2019, 4:43:20 AM7/16/19
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col...@gmail.com wrote in
news:aab3ebc3-e7fa-4ea6...@googlegroups.com:
Yeah, several studies show this. I tried it and even a small amount
raised my BP. Since high BP is a significant factor in kidney function
decline, not sure it is worth doing. Why pay peter to pay paul? Of course
I am not taking BP medicine as my BP is excellent at 115/70. Can go up
130-140 due to increased consumption of sodium bicarbonate. Current
guidelines say keep BP below 120 if you have CKD.

col...@gmail.com

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Jul 16, 2019, 6:29:54 AM7/16/19
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My bp is often too low anyway.

hohum

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Jul 20, 2019, 6:20:54 AM7/20/19
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col...@gmail.com wrote in news:5a96a07a-7cfc-445e-8ef7-e69d98d85de7
@googlegroups.com:

> My bp is often too low anyway.
>
And that's a symptom of CKD. Even the studies on this show significant
increases in BP with bicarbonate supplementation. They just ignore it.

col...@gmail.com

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Jul 20, 2019, 5:47:55 PM7/20/19
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On Sunday, June 30, 2019 at 8:08:22 PM UTC-4, col...@gmail.com wrote:
> More recently, a 5-year prospective, randomized, placebo-controlled blinded interventional study tested if daily oral sodium bicarbonate slowed GFR decline in patients with hypertensive nephropathy with reduced but relatively preserved estimated GFR (eGFR) (mean 75 ml/min per 1.73 m2). Participants matched for age, ethnicity, albuminuria, and eGFR received either daily placebo (n=40), equimolar sodium chloride (n=40), or sodium bicarbonate (n=40) while being maintained on their antihypertensive regimens (including angiotensin-converting enzyme [ACE] inhibition) treated to conventional BP targets. In keeping with their relatively preserved renal function, participants were not acidotic at enrollment with a mean total CO2 in ≥26 mmol/L. After 5 years, the rate of eGFR decline, estimated using plasma cystatin C, was slower and eGFR significantly higher in patients receiving sodium bicarbonate (baseline cysGFR [in ml/min per 1.73 m2], 73.2; after 5 years, 66.4) than in those given placebo (baseline, 73.5; after 5 years, 60.8) or sodium chloride (baseline, 73.5; after 5 years, 62.7). This interesting study calls for use of sodium bicarbonate in patients with early CKD even in the absence of overt acidosis (17).





I only take 1/4 tsp which isn't much.

col...@gmail.com

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Jul 21, 2019, 7:40:44 AM7/21/19
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I think my cystatin C gfr would be higher than my creatinine 1 is.

blowme

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Aug 5, 2019, 3:45:02 PM8/5/19
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col...@gmail.com wrote in
news:56688ee0-2fa2-40c4...@googlegroups.com:
KEEP a close look on you BP when doing this. The new guidelines are blow
120 and below 80 I believe. Don't rob Peter to pay Paul
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