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The role of aluminum in autism and neurodegeneration
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Kofi
May 30, 2013, 3:49:21 AM5/30/13
to
When mercury-based adjuvants (Thimerosal) were supposedly ruled out as a
cause of autism, they were, in fact, merely compared to aluminum-based
adjuvant vaccines (alum). All this proved was that the two adjuvants
were equivalent in their provocation of autism in the patient
population. No one ever actually bothered to compare adjuvant-based
vaccines against non-adjuvant vaccines.
Although the thought has been on my mind since the controversy was
supposedly settled by these innumerate individuals, this is the first
paper I've ever come across indicating aluminum-based vaccines cause
autism and hinting at the design flaw in these studies exonerating
mercury.
Adjuvants are added to provoke the immune system and to save money on
the amount of antigens put into the vaccines. Companies add much less
antigen and throw in an adjuvant to provoke immune cells into
overreacting. Even if these adjuvants are the main source of
vaccine-induced autism, it may well be the case that some small number
of patients react to the antigens themselves but these may be
immunoregulatory problems best dealt with via other means (like
helminths).
If you fail to get vaccinations - even with the risks posed by their
adjuvants - this decision in and of itself will drive up your risk of
autism and schizophrenia, either in you or your children. Both of these
diseases are closely correlated with viral infections, which you will be
at greater risk of getting without these vaccinations.
Aluminum in the central nervous system (CNS): toxicity in humans and
animals, vaccine adjuvants, and autoimmunity.
Shaw CA, Tomljenovic L.
Immunol Res. 2013 Apr 23. [Epub ahead of print]
Neural Dynamics Research Group, Department of Ophthalmology and Visual
Sciences, University of British Columbia (UBC), 828 W. 10th Ave.,
Vancouver, BC, V5Z 1L8, Canada, cash...@gmail.com.
We have examined the neurotoxicity of aluminum in humans and animals
under various conditions, following different routes of administration,
and provide an overview of the various associated disease states. The
literature demonstrates clearly negative impacts of aluminum on the
nervous system across the age span. In adults, aluminum exposure can
lead to apparently age-related neurological deficits resembling
Alzheimer's and has been linked to this disease and to the Guamanian
variant, ALS-PDC. Similar outcomes have been found in animal models. In
addition, injection of aluminum adjuvants in an attempt to model Gulf
War syndrome and associated neurological deficits leads to an ALS
phenotype in young male mice. In young children, a highly significant
correlation exists between the number of pediatric aluminum-adjuvanted
vaccines administered and the rate of autism spectrum disorders. Many of
the features of aluminum-induced neurotoxicity may arise, in part, from
autoimmune reactions, as part of the ASIA syndrome.
PMID 23609067 [PubMed - as supplied by publisher]
Full text: Springer
* Aluminum hydroxide injections lead to motor deficits and motor neuron
degeneration.
* Aluminum adjuvant linked to Gulf War illness induces motor neuron
death in mice.
* Mechanisms of aluminum adjuvant toxicity and autoimmunity in
pediatric populations.
* Do aluminum vaccine adjuvants contribute to the rising prevalence of
autism?
* Autoimmunity following hepatitis B vaccine as part of the spectrum of
'Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants' (ASIA):
analysis of 93 cases.
cause of autism, they were, in fact, merely compared to aluminum-based
adjuvant vaccines (alum). All this proved was that the two adjuvants
were equivalent in their provocation of autism in the patient
population. No one ever actually bothered to compare adjuvant-based
vaccines against non-adjuvant vaccines.
Although the thought has been on my mind since the controversy was
supposedly settled by these innumerate individuals, this is the first
paper I've ever come across indicating aluminum-based vaccines cause
autism and hinting at the design flaw in these studies exonerating
mercury.
Adjuvants are added to provoke the immune system and to save money on
the amount of antigens put into the vaccines. Companies add much less
antigen and throw in an adjuvant to provoke immune cells into
overreacting. Even if these adjuvants are the main source of
vaccine-induced autism, it may well be the case that some small number
of patients react to the antigens themselves but these may be
immunoregulatory problems best dealt with via other means (like
helminths).
If you fail to get vaccinations - even with the risks posed by their
adjuvants - this decision in and of itself will drive up your risk of
autism and schizophrenia, either in you or your children. Both of these
diseases are closely correlated with viral infections, which you will be
at greater risk of getting without these vaccinations.
Aluminum in the central nervous system (CNS): toxicity in humans and
animals, vaccine adjuvants, and autoimmunity.
Shaw CA, Tomljenovic L.
Immunol Res. 2013 Apr 23. [Epub ahead of print]
Neural Dynamics Research Group, Department of Ophthalmology and Visual
Sciences, University of British Columbia (UBC), 828 W. 10th Ave.,
Vancouver, BC, V5Z 1L8, Canada, cash...@gmail.com.
We have examined the neurotoxicity of aluminum in humans and animals
under various conditions, following different routes of administration,
and provide an overview of the various associated disease states. The
literature demonstrates clearly negative impacts of aluminum on the
nervous system across the age span. In adults, aluminum exposure can
lead to apparently age-related neurological deficits resembling
Alzheimer's and has been linked to this disease and to the Guamanian
variant, ALS-PDC. Similar outcomes have been found in animal models. In
addition, injection of aluminum adjuvants in an attempt to model Gulf
War syndrome and associated neurological deficits leads to an ALS
phenotype in young male mice. In young children, a highly significant
correlation exists between the number of pediatric aluminum-adjuvanted
vaccines administered and the rate of autism spectrum disorders. Many of
the features of aluminum-induced neurotoxicity may arise, in part, from
autoimmune reactions, as part of the ASIA syndrome.
PMID 23609067 [PubMed - as supplied by publisher]
Full text: Springer
* Aluminum hydroxide injections lead to motor deficits and motor neuron
degeneration.
* Aluminum adjuvant linked to Gulf War illness induces motor neuron
death in mice.
* Mechanisms of aluminum adjuvant toxicity and autoimmunity in
pediatric populations.
* Do aluminum vaccine adjuvants contribute to the rising prevalence of
autism?
* Autoimmunity following hepatitis B vaccine as part of the spectrum of
'Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants' (ASIA):
analysis of 93 cases.
Trawley Trash
May 30, 2013, 12:10:08 PM5/30/13
to
On Thu, 30 May 2013 02:49:21 -0500
Kofi <ko...@anon.un> wrote:
> If you fail to get vaccinations - even with the risks posed by their
> adjuvants - this decision in and of itself will drive up your risk of
> autism and schizophrenia, either in you or your children. Both of
> these diseases are closely correlated with viral infections, which
> you will be at greater risk of getting without these vaccinations.
Yes viral infections can cause autoimmune conditions such as autism.
Kofi <ko...@anon.un> wrote:
> If you fail to get vaccinations - even with the risks posed by their
> adjuvants - this decision in and of itself will drive up your risk of
> autism and schizophrenia, either in you or your children. Both of
> these diseases are closely correlated with viral infections, which
> you will be at greater risk of getting without these vaccinations.
Not so sure about schizophrenia; it is often misdiagnosed. Vaccines
affect the immune system in the same way. So do you have any data
backing up your claim, or is it just based on what seems to be
circular reasoning?
Kofi
Jun 4, 2013, 10:31:26 PM6/4/13
to
In article <08ak7a-...@jammer.gnet>, Trawley Trash
Schizophrenia can be an autoimmune condition. There are autoantibodies
associated with it.
Faulty DISC1 signaling is associated with schizophrenia. DISC1 is also
targeted by viruses for entry into the cell nucleus [PMID 18552348]
in mice, second trimester prenatal influenza viral infection upregulates
FoxP2 and Sema3a; FoxP2 is upregulated in P35 cerebellum of exposed mice
of Balb/c dams infected on E9; Foxp2 protein was upregulated
significantly in P0 and P35 cerebellum of exposed mouse progeny; sema3a
mRNA is elevated in the cereballa of schizophrenics and is elevated 3.5x
in hippocampi of offspring of exposed mice at P0; upregulation of Foxp2
protein occurs in both cerebellum (P0, P35) and hippocampus (P35, P56)
of the progeny of virally exposed mice; serotonin has neurotrophic
effects during embryogenesis; serotonin levels were reduced
significantly in postnatal days 14 and 35; schizophrenics have serotonin
receptor abnormalities; serotonin metabolite 5HIAA dropped significantly
in postnatal day 14 and nonsignificantly in postnatal day 35; evidence
points to first trimester infection for autism risk and second trimester
for schizophrenia [PMID 18248790]
Many investigations suggest that abnormalities of the immune system are
involved in the pathophysiology of schizophrenia. We recently found
increased activity of leukocyte elastase (LE) and elevated levels of
autoantibodies to neurospecific protein - nerve growth factor (Aab to
NGF) - products of the innate and adaptive arms of the immune system in
the serum of patients with acute stage schizophrenia. The aim of this
study is to elucidate whether or not the changes of LE activity and Aab
to NGF level are related to prominent features of schizophrenia.
Patients (n=71) corresponding to ICD-10 criteria for relapse-remitting
schizophrenia were assessed by the Positive and Negative Syndrome Scale
(PANSS). Patients with predominantly positive symptoms showed
significantly elevated serum levels of Aab to NGF compared to patients
with predominantly negative symptoms, who were more likely to exhibit
the high LE activity. Moreover, progression of positive symptoms was
coupled with gradual increase of Aab to NGF level and reduction of LE
activity. Based on these findings we conclude that the high levels of
Aab to NGF relate to a clinical picture characterised mainly by positive
symptoms of schizophrenia, whereas high LE-activities relate to a
clinical picture with mainly negative symptoms of schizophrenia [PMID
15346538]
associated with it.
Faulty DISC1 signaling is associated with schizophrenia. DISC1 is also
targeted by viruses for entry into the cell nucleus [PMID 18552348]
in mice, second trimester prenatal influenza viral infection upregulates
FoxP2 and Sema3a; FoxP2 is upregulated in P35 cerebellum of exposed mice
of Balb/c dams infected on E9; Foxp2 protein was upregulated
significantly in P0 and P35 cerebellum of exposed mouse progeny; sema3a
mRNA is elevated in the cereballa of schizophrenics and is elevated 3.5x
in hippocampi of offspring of exposed mice at P0; upregulation of Foxp2
protein occurs in both cerebellum (P0, P35) and hippocampus (P35, P56)
of the progeny of virally exposed mice; serotonin has neurotrophic
effects during embryogenesis; serotonin levels were reduced
significantly in postnatal days 14 and 35; schizophrenics have serotonin
receptor abnormalities; serotonin metabolite 5HIAA dropped significantly
in postnatal day 14 and nonsignificantly in postnatal day 35; evidence
points to first trimester infection for autism risk and second trimester
for schizophrenia [PMID 18248790]
Many investigations suggest that abnormalities of the immune system are
involved in the pathophysiology of schizophrenia. We recently found
increased activity of leukocyte elastase (LE) and elevated levels of
autoantibodies to neurospecific protein - nerve growth factor (Aab to
NGF) - products of the innate and adaptive arms of the immune system in
the serum of patients with acute stage schizophrenia. The aim of this
study is to elucidate whether or not the changes of LE activity and Aab
to NGF level are related to prominent features of schizophrenia.
Patients (n=71) corresponding to ICD-10 criteria for relapse-remitting
schizophrenia were assessed by the Positive and Negative Syndrome Scale
(PANSS). Patients with predominantly positive symptoms showed
significantly elevated serum levels of Aab to NGF compared to patients
with predominantly negative symptoms, who were more likely to exhibit
the high LE activity. Moreover, progression of positive symptoms was
coupled with gradual increase of Aab to NGF level and reduction of LE
activity. Based on these findings we conclude that the high levels of
Aab to NGF relate to a clinical picture characterised mainly by positive
symptoms of schizophrenia, whereas high LE-activities relate to a
clinical picture with mainly negative symptoms of schizophrenia [PMID
15346538]
Trawley Trash
Jun 5, 2013, 10:59:36 AM6/5/13
to
On Tue, 04 Jun 2013 21:31:26 -0500
Kofi <ko...@anon.un> wrote:
> Schizophrenia can be an autoimmune condition. There are
> autoantibodies associated with it.
Many forms of brain damage are diagnosed as schizophrenia:
Kofi <ko...@anon.un> wrote:
> Schizophrenia can be an autoimmune condition. There are
> autoantibodies associated with it.
usually without any physical exam or lab tests.
If the cause is an autoimmune condition, then this is an
allergy not a mental illness. Unfortunately it is difficult
to find psychiatrists or allergists who are not quacks.
Jeffer05
Jul 29, 2013, 10:18:31 PM7/29/13
to
(for some reason I can't seem to post from my other account, I tried a
few times and don't see it, if eventually they pop up my apologies for
the multiple posts)
If this is true I find it absolutely incredible, but not surprising. As
an analogy it's like they are justifying giving you one poison because
in their tests it's no worse when compared to another poison. So
therefore their conclusion is that it's safe because it's no worse then
another substance which is equally noxious.
A clear case of trying to protect their bottom line. The entire issue of
using these so called adjuvants seems suspect to me. Mercury? Aluminum?
are these things we should be injecting into our bodies, or worse, our
children's bodies??? This doesn't even come close to sounding anything
other than completely crazy. And of course the final justification is if
you don't get these vaccines you are putting yourself at even greater
risk. Nothing like the old Fear Factor to scare people into taking
potentially harmful substances. Damned if you do, damned if you don't,
either way you will pay.
thanks for the post, I hope this gets more recognition in the medical
and scientific communities. Would be great if they did as postulated and
tested the mercury and aluminum against a non-adjuvant vaccine. That
would tell the real tale.
regards,
Jeff
few times and don't see it, if eventually they pop up my apologies for
the multiple posts)
If this is true I find it absolutely incredible, but not surprising. As
an analogy it's like they are justifying giving you one poison because
in their tests it's no worse when compared to another poison. So
therefore their conclusion is that it's safe because it's no worse then
another substance which is equally noxious.
A clear case of trying to protect their bottom line. The entire issue of
using these so called adjuvants seems suspect to me. Mercury? Aluminum?
are these things we should be injecting into our bodies, or worse, our
children's bodies??? This doesn't even come close to sounding anything
other than completely crazy. And of course the final justification is if
you don't get these vaccines you are putting yourself at even greater
risk. Nothing like the old Fear Factor to scare people into taking
potentially harmful substances. Damned if you do, damned if you don't,
either way you will pay.
thanks for the post, I hope this gets more recognition in the medical
and scientific communities. Would be great if they did as postulated and
tested the mercury and aluminum against a non-adjuvant vaccine. That
would tell the real tale.
regards,
Jeff
Vanny
Jul 30, 2013, 5:44:09 AM7/30/13
to
Thimerosal is an anti-fungal and antiseptic agent and is added to
vaccines as a preservative. There is no reference in the literature (I
have read) to it being used as an adjuvant per se.
They were probably testing a vaccine with an aluminium-adjuvant and
mercury-based preservative, against a vaccine with an aluminium adjuvant
and non-mercury-based preservative.
It is noteworthy that thiomersal (aka thimersal, thiomerosal,
thiomersalmercurothiolate and sodium 2-ethylmercuriothio-benzoate) is
also found in tattoo inks, antivenins, and ear and eye products.
Vanny
References
http://www.who.int/vaccine_safety/committee/topics/thiomersal/questions/en/
http://www.personalinjury.com/thimerosal-thiomersal.html
http://www.speciation.net/News/FDA-Will-Review-Toxic-Tattoo-Chemicals-;~/2008/10/02/3837.html
For the tattooed or soon to be tattooed, these articles are worth reading:
http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm048919.htm
http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm316357.htm
vaccines as a preservative. There is no reference in the literature (I
have read) to it being used as an adjuvant per se.
They were probably testing a vaccine with an aluminium-adjuvant and
mercury-based preservative, against a vaccine with an aluminium adjuvant
and non-mercury-based preservative.
It is noteworthy that thiomersal (aka thimersal, thiomerosal,
thiomersalmercurothiolate and sodium 2-ethylmercuriothio-benzoate) is
also found in tattoo inks, antivenins, and ear and eye products.
Vanny
References
http://www.who.int/vaccine_safety/committee/topics/thiomersal/questions/en/
http://www.personalinjury.com/thimerosal-thiomersal.html
http://www.speciation.net/News/FDA-Will-Review-Toxic-Tattoo-Chemicals-;~/2008/10/02/3837.html
For the tattooed or soon to be tattooed, these articles are worth reading:
http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm048919.htm
http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm316357.htm
Kofi
Apr 2, 2014, 5:05:42 AM4/2/14
to
However they describe it, mercury can and does stimulate immune cells
and thus can act as an adjuvant.
Mercury tissue deposits: a new adjuvant in autoimmune/inflammatory
syndrome.
Cruz-Domínguez MP, Vera-Lastra O, Deras-Quiñones A, Jandete-Rivera F,
Grajeda-Lopez P, Montes-Cortes DH, Medina G, Jara LJ.
Isr Med Assoc J. 2013 Nov;15(11):716-9.
PMID 24511657 [PubMed - indexed for MEDLINE]
Free full text: Israel Medical Association
In article <kt81sl$p0u$1...@newsreader4.netcologne.de>, Vanny
and thus can act as an adjuvant.
Mercury tissue deposits: a new adjuvant in autoimmune/inflammatory
syndrome.
Cruz-Domínguez MP, Vera-Lastra O, Deras-Quiñones A, Jandete-Rivera F,
Grajeda-Lopez P, Montes-Cortes DH, Medina G, Jara LJ.
Isr Med Assoc J. 2013 Nov;15(11):716-9.
PMID 24511657 [PubMed - indexed for MEDLINE]
Free full text: Israel Medical Association
In article <kt81sl$p0u$1...@newsreader4.netcologne.de>, Vanny
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