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Bactrim does it again

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Ozzie Neroni

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Feb 9, 1998, 3:00:00 AM2/9/98
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Some time back ago I posted that my three year old battle with
ulcerative colitis/possibly Chrons was seemingly cured with the
antibiotic Bactrim---taken originally for a sinus infection. Well,
after taking each of three doses, the difficulties would reoccur
(primarily bleeding) within about a week after terminating its intake.
Tests at the local hospital lab could detect no bacteria present. My GI
refuses to believe that a bacteria could be responsible for the problem.
My GP acknowledges that three successful tries of taking Bactrim
demonstrates more than mere coincidence the antibiotic's beneficial
effects for me and has prescribed what is now the fourth dose, but this
time instead of completely ceasing the medication--- to instead
gradually reduce the intake until the minimum amount required to keep it
under control is attained. I'm into about one week of taking the fourth
prescription and find that the symptoms are practically gone already.
After this first phase I will cut the dose in half and repeat until the
minimum amount is realized. Also suggested was the possibility of going
to the Cleveland Clinic to attempt to determine exactly what the nasty
bug is precisely that is digging holes into my innards. Curiosly, it
was by accident that the discovery was made that the Bactrim seemed to
be the answer. Posts in reply to my previous post suggested that the
bacteria culprit may be M. Paratuberculosis. Does anyone know, or has
heard, if Bactrim has had such results with that particular bacteria?
And finally, and just a thought, was it not the GI's, as a group, that
refused to believe at first that a bacteria could be the cause of
certain stomach ulcers? Ozzie Neroni

PATSYCATS

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Feb 10, 1998, 3:00:00 AM2/10/98
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Hi Ozzie,

I'm so glad that the Bactrim is helping you feel better. Obviously, using
Bactrim is getting your symptoms down to a minimum. Is the unknown bacteria
actually the cause of your Chron's disease, though? Maybe. But another
possibility is that the presence of a bacteria (maybe combined with undigested
food) is causing a flare-up of your underlying disease. Keep us posted.

Patsy

Margie

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Feb 10, 1998, 3:00:00 AM2/10/98
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Bactrim helped me, too, a few years ago. Then I started to get hives every
time I started the pills...so, I am back to square one. My gastro Dr. told
me that he thought Bactrim helped other people, too. It is not a
coincidence; wish I could take the antibiotic. I cannot take any meds that
have sulfa in them either because I get hives. There must be another drug
out there, but I just haven't found it yet. Biaxin is one that works pretty
well though with very little side effects...other than a little
constipation, which is okay.

Sue

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Feb 10, 1998, 3:00:00 AM2/10/98
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Isn't Bactrim a sulfa-based medication? Despite all the talk about
the sulfa in sulfasalazine merely being used as a delivery vehicle
for the mesalamine, I have heard doctors (at CCFA meetings yet) say
that they thought the sulfa component helped IBD too, either by
killing off normal bacteria in the gut that we are abnormally
reacting too or by attacking some yet undiscovered germ. It's
worth getting fully tested for parasites etc. in your case though
just to rule better known causes of diarrhea, although you'll have
to stop taking the Bactrim and wait until you're sick again, plus
to be pretty sure of ruling things out you have to have multiple
stool samples and go to a really good lab.


Sue s...@panix.com

sarah

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Feb 10, 1998, 3:00:00 AM2/10/98
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I am not sure of this but isn't bactrim a sulfa drug. And isn't sulfa used in some of
the ASA drugs. And I think it is used in intestinal bleeding in animals.
Does anyone else know about this ? If I get to the library tomorrow I will try and look
it up in the PDR. Keep it up Ozzie and let us know how it goes.

LavendrNan

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Feb 11, 1998, 3:00:00 AM2/11/98
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In article <6br4h5$7...@panix3.panix.com>, s...@panix.com (Sue) writes:

>Isn't Bactrim a sulfa-based medication?

Yes - it's generic name is sulfamethoxazole.
Non-commercial HOTMAIL, JUNO, or MSN users can contact me at
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above.

Kevin McFerrin

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Feb 11, 1998, 3:00:00 AM2/11/98
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Yep...some stomach ulcers are caused by H.Pylori. Mine were...after a
series of bad upper respiratory infections which were treated with high
levels of antibiotics (I'm thinking Biaxin in this case), they symptoms went
away.
And I think I remember reading somewhere that Biaxin has had some
limited effect on the symptoms of CD as well...I'll have to find where I
read, or thought that I read, that.


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