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Iron And Breast Cancer

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ironjustice

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Nov 11, 2009, 4:42:09 AM11/11/09
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Dietary intake and serum levels of iron in relation to oxidative
stress
in breast cancer patients.
Bae YJ, Yeon JY, Sung CJ, Kim HS, Sung MK.
J Clin Biochem Nutr. 2009 Nov;45(3):355-60. Epub 2009 Oct 28.
Department of Food and Nutrition, Sookmyung Women's University,
Seoul 140-742, Republic of Korea.

Iron may induce oxidative stress via production of reactive oxygen
species,
facilitating mammary carcinogenesis.
This study investigated the role of iron in relation to oxidative
stress as a
potential risk factor in the development of breast cancer (BC).
BC patients (n = 121) and healthy age-matched controls (n = 149) were
entered into the study.
Iron and antioxidant vitamins intakes were estimated using a
quantitative
food frequency questionnaire.
Thirty one subjects from each group provided blood samples for
measurement of serum iron, plasma malondialdehyde (MDA) and ferric
reducing ability of plasma (FRAP).
Total and non-heme iron intake of BC patients were lower than those of
the
controls.
However, the serum iron level was significantly higher in BC
patients.
Plasma MDA levels were also significantly higher in BC patients
whereas no
significant difference in FRAP values were observed between the two
groups.
Log-transformed serum iron concentration showed no significant
correlation
with MDA or FRAP.
These results suggest that serum iron overload may be a breast cancer
risk
factor possibly due to increased oxidative stress.

PMID: 19902028


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Nov 11, 2009, 7:57:41 AM11/11/09
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"Total and non-heme iron intake of BC patients were lower than those of
the controls."

Oops, there goes the eating meat and its iron causes all disease idea
right down the crapper.

If the idea had merit the results as above would have been exactly
oppisite.

Agood post to consider for the iron hall of shame. That being a set of
posts which causes great foot pain, as the poster shoots himself in the
foot with his own posts.

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