Oxidative Stress And Plant Pigments
ironjustice
Stress and Neurotransmitter Status
J. Agric. Food Chem., 56 (16), 7545–7550, 2008.
Effects of Anthocyanins on Psychological Stress-Induced Oxidative
Stress and Neurotransmitter Status
M. Mamunur Rahman,† Takashi Ichiyanagi,‡ Tadazumi Komiyama,‡ Shinji
Sato,† and Tetsuya Konishi*†
Faculty of Applied Life Sciences, Faculty of Pharmaceutical Sciences,
Niigata University of Pharmacy and Applied Life Sciences, 265-1
Higashijima, Niigata 956-8603, Japan
Received for review March 26, 2008. Revised manuscript received May
26, 2008. Accepted June 23, 2008. This study was supported in part by
a Grant in Aid from AOA Japan Co., LTD., and also from the Uchida
Science Promotion Foundation, Niigata, Japan.
Abstract:
There is strong evidence that oxidative stress participates in the
etiology of neurodegenerative diseases such as Parkinson’s, and
Alzheimer’s diseases.
Moreover, emotional stress effects in the central nervous system play
a vital role in homeostasis.
The protective effect of anthocyanins on the cerebral oxidative
stress
was studied using the whiskers cut model.
In mice, such treatment causes psychological or emotional distress
leading to oxidative stress in tissues.
To investigate the in vivo antioxidant activity of anthocyanins, an
extract of Vaccinium myrtillis L., an anthocyanin mixture, was orally
administered (100 mg/kg of body weight.) to mice for 7 days, and then
psychological stress was assessed by cutting off their whiskers.
Whisker removal increased both protein carbonyl formation and lipid
peroxidation in the brain, heart, kidney, and liver.
Further, the levels of oxidative markers showed regional differences
in the brain.
Concomitantly, dopamine neurotransmitter levels were altered in both
the midbrain and the brain cortex.
Orally administered anthocyanins were also active in the brain,
suppressing stress-induced cerebral oxidative stress and dopamine
abnormalities in distressed mice.
These effects of anthocyanin treatment suggest their possible
usefulness for the treatment of cerebral disorders related to
oxidative stress.
Keywords: Anthocyanin; antioxidant activity; psychological stress;
dopamine.
10.1021/jf800930s
Web Release Date: July 29, 2008
Copyright © 2008 American Chemical Society
--------------------
http://www.chiro.org/nutrition/FULL/Anthocyanins.shtml
From the December 2001 Issue of Nutrition Science News
By Marilyn Sterling, R.D.
These plant pigments are more than coloring agents for fruit juices,
wine, and other beverages. They also contain an array of health-
promoting benefits.
Eaten in large amounts by primitive humans, anthocyanins are
antioxidant flavonoids that protect many body systems.
They have some of the strongest physiological effects of any plant
compounds, and they are also things of beauty: anthocyanins provide
pigment for pansies, petunias, and plums. (Anthocyanins are a
separate
class of flavonoids from proanthocyanidins, discussed in NSN
2000;5(6):
231-4.)
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
I M Portant
internet
ironjustice
Where do you get the articles you post .. ?
You .. don't .. post .. articles .. ?
Well I bet everyone is glad to hear then .. that .. **I** post
articles from the internet ..?
I think they are already aware of that ..
You might be a little slow on the uptake there .. big guy ..
Heh .. heh ..
Let me guess your next revelation .. ?
"He uses a computer!!" ..
Michael B
food that contains a derivative of the anthocyanidin delphinidin
which interferes with the dangerous hydroxyl radical-generating
system—a major source of oxidants in the body? I would have
thought you would have been touting that a long time ago.
Hint-it's from one of the nightshades.
And, BTW, anyone else is welcome to join me in our thread.
Shucks, we all know by now that if Rusty didn't want me on
the threads he starts, he wouldn't include alt.med.fibromyalgia
in the initial crosspostings.
Does everyone also know what the hydroxyl radical is? Some of
you don't? Why, that's disappointing. But since Rusty is so set
on telling us about oxidative stress, perhaps you can prevail on
him to explain it. After all, it's near the root of it all.
Go ahead, ask him to explain it. He's really waiting for a good
opportunity to make sure you all understand it as well as he
does.
> --------------------http://www.chiro.org/nutrition/FULL/Anthocyanins.shtml
ironjustice
Lefty .. what were you told to do ...
Who loves ya.
Tom
Michael B
invitation to join in? Well, here I am.
If you...can't...get...that, you're more stupid than I even imagined.
ironjustice
Lefty .. what were you told to do ...
Paul T. Holland
multiple postings of the same information, article, or message in such a
repetative manner IS considered spam
ironj...@aol.com
Paul T. Holland
Michael B
Only point is his head.
On Aug 21, 7:22 pm, "Paul T. Holland" <pholl...@bellatlantic.net>
wrote:
> well, that answers that - 'knowingly' reposting -
>
Paul T. Holland
purposes of forwarding to abuse/complaint desks, you have to be able to
show just what is at issue.
for that purpose, leaving the threaded messages intact without snipping
the multiple reposting of original message article is useful. boring,
wasted bandwidth - but useful.
ironj...@aol.com
Anthocyanins Inhibit Nuclear Factor-B Activation in Monocytes and
Reduce
J. Nutr. 137:1951-1954, August 2007
Plasma Concentrations of Pro-Inflammatory Mediators in Healthy Adults
1–3,Anette Karlsen4, Lars Retterstøl6, Petter Laake5, Ingvild Paur4,
Siv Kjølsrud-Bøhn4, Leiv Sandvik7 and Rune Blomhoff4,*
4 Department of Nutrition, and 5 Department of Biostatistics,
Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
N-0316 and 6 Department of Medical Genetics and 7 Research Centre,
Ullevaal University Hospital, Oslo, Norway N-0407
* To whom correspondence should be addressed. E-mail:
rune.b...@medisin.uio.no.
ABSTRACT
The transcription factor nuclear factor-B (NF-B) is activated by
oxidative stress and pro-inflammatory stimuli and controls the
expression of numerous genes involved in the inflammatory response.
Dampening NF-B activation and thereby limiting the inflammatory
response have been suggested as a potential strategy to prevent
chronic inflammatory diseases. In cultured monocytes, anthocyanins
isolated from bilberries and black currants (Medox) efficiently
suppressed LPS-induced activation of NF-B.
Furthermore, we studied the effect of anthocyanin supplementation
(Medox, 300 mg/d for 3 wk) in a parallel-designed, placebo-controlled
clinical trial (n = 120 men and women aged 40–74 y).
Differences were observed in several NF-B related inflammatory
mediators in the Medox group compared to placebo.
The changes in the NF-B-controlled pro-inflammatory chemokines IL-8,
"regulated upon activation, normal T cell expressed and
secreted," (RANTES) and IFN (an inducer of NF-B activation) in the
Medox group (45, 15, and 40% decreases from baseline, respectively)
differed from those in the placebo group (20, 0, and 15% decreases
from baseline, respectively) (P < 0.050).
Similarly, changes in IL-4 and IL-13, 2 cytokines that mediate pro-
inflammatory responses and induce NF-B activation, in the Medox group
(60 and 38% decreases from baseline, respectively) tended to differ
from those in the placebo group (4 and 6% decreases) (P = 0.056 and, P
= 0.089, respectively).
These data suggest that anthocyanin supplementation may have a role in
the prevention or treatment of chronic inflammatory diseases by
inhibition of NF-B transactivation and deceased plasma concentrations
of pro-inflammatory chemokines, cytokines, and inflammatory mediators.
© 2007 American Society for Nutrition
--------------------------------------------------------------------------------
wrtho...@gmail.com
> but another point is that if one is interested in using these posts for
> purposes of forwarding to abuse/complaint desks, you have to be able to
> show just what is at issue.
> for that purpose, leaving the threaded messages intact without snipping
> the multiple reposting of original message article is useful. boring,
> wasted bandwidth - but useful.
If anyone wants to forward an abuse complaint, they can use the
original post. Abuse departments want the original post, complete
with
headers. All you do by reposting Ferrous Hilton's unclipped trash
is to give him what he wants.
Has anyone figured out what he's saying in those URLs of his?
I've looked at them, and despite the labels they have nothing to
do with his imaginary childhood friends. Is he trying to sell
biphosphonate, or whatever else he's fixated on? If so he can
be turned in for commercial spam.
--Bill Thompson
ironj...@aol.com
wrote:unclipped trash <<
Hey willy boi ..
Don't be clipping my posts .. understand .. ?
YOU would know trash when you see it .. wouldn't ya ..
Seeing that you are nothing but a piece of trash .. yourself .. eh ..
Heh .. heh ..
How's that .. feeeeeel .. boi ..
To BE .. trash ..
------------------------------
"Prevention or treatment of chronic inflammatory diseases"
Anthocyanins Inhibit Nuclear Factor-B Activation in Monocytes and
Reduce
J. Nutr. 137:1951-1954, August 2007
Plasma Concentrations of Pro-Inflammatory Mediators in Healthy Adults
1–3,Anette Karlsen4, Lars Retterstøl6, Petter Laake5, Ingvild Paur4,
Siv Kjølsrud-Bøhn4, Leiv Sandvik7 and Rune Blomhoff4,*
4 Department of Nutrition, and 5 Department of Biostatistics,
Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
N-0316 and 6 Department of Medical Genetics and 7 Research Centre,
Ullevaal University Hospital, Oslo, Norway N-0407
* To whom correspondence should be addressed. E-mail:
--------------------------------------------------------------------------------
wrtho...@gmail.com
> Hey willy boi ..
> Don't be clipping my posts .. understand .. ?
Or what? You'll tell your imaginary childhood friend about me?
> YOU would know trash when you see it .. wouldn't ya ..
I'm sure I'll recognize you if I ever see you, Rusty.
> Seeing that you are nothing but a piece of trash .. yourself .. eh ..
> Heh .. heh ..
>
> How's that .. feeeeeel .. boi ..
> To BE .. trash ..
You're the expert on being trash, Rusty. Why don't I forward your
post to ab...@telus.net and see how they feel about it?
--Bill Thompson
ironj...@aol.com
wrote: trash <<
How's that .. feeeeeel .. boi ..
To BE .. trash ..
wrtho...@gmail.com
> On Aug 23, 10:22 am, "wrtho...@ix.netcom.com" <wrthomp...@gmail.com>
> wrote: trash <<
>
> How's that .. feeeeeel .. boi ..
>
> To BE .. trash ..
I feel rather good after forwarding your post to ab...@telus.net.
--Bill Thompson
ironj...@aol.com
wrote:trash <<
Stay off my threads ..
You are .. **trash** .. ..
Planta Med 2008; 74
DOI: 10.1055/s-0028-1084882
Total content of phenols and anthocyanins in fruits from Bosnia
J Toromanovic 1, I Tahirovic 1, E Toromanovic 2, A Sapcanin 1, A
Uzunovic 4, S Selman 1, E Sofic 1, 3
1 Faculty of Science, University of Sarajevo, Bosnia and Herzegovina
2 Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina
3 Faculty of Pharmacy, University of Sarajevo, Bosnia and Herzegovina
4 Institute for Control of Drugs, Ministry of Health, Federation of
Bosnia and Herzegovina, Sarajevo
AIM: The aim of this study was to determine the total content of
phenols and anthocyanins in some fruits. Methods: The content of total
phenols was estimated by a spectrophotometric method using gallic acid
as a standard. The content of total anthocyanins was measured using a
pH differential spectrophotometric method. Ideain chloride was used as
a standard for determination of anthocyanins. Results: The total
content of phenols in red currant fruits was 8,4mg/g, dried cranberry
8,2mg/g, cranberry 7,5mg/g, black mulberry fruit 7,3mg/g, wild cherry
6,9mg/g, hawthorn 6,4mg/g, wild bilberry 5,8mg/g, black currant 5,2mg/
g, dried prunes 5,1mg/g, drain 3,5mg/g, and prunes 3,4mg/g. The lowest
quantity of total phenols was found in cultivated strawberries. It was
only 2,1mg/g. The total anthocyanins content in wild bilberry was
2030µg/g, wild cherry 1540µg/g, dried cranberry 1400µg/g, black
currant 822µg/g, cranberry 400µg/g, cultivated strawberries 260µg/g,
black mulberry fruit 240µg/g, drain 160µg/g, red currant 147µg/g,
hawthorn 80µg/g, prunes 50µg/g and in dried prunes 10µg/g. CONCLUSION:
The highest content of total phenols was in red currant and the lowest
in cultivated strawberries. The highest content of total anthocyanins
was in wild bilberry and the lowest in dried prunes. The
spectrophotometric methods for determination of total phenols and
anthocyanins appear to be a valid and useful procedure for analysis of
phenols and anthocyanins in supernatants of fruits.
ironj...@aol.com
wrote:anthocyanins <<
Potential neuroprotective role of anthocyanins and anthocyanidins
mediated by proteasome inhibition
Pharmacopsychiatry 2007; 40
A Dreiseitel 1, P Schreier 2, G Hajak 1, PG Sand 1
1 Department of Psychiatry, University of Regensburg, Germany
2 Chair of Food Chemistry, University of Wuerzburg, Germany
Objective: Recent reports have demonstrated multiple benefits
associated with the consumption of blueberries, including decreased
vulnerability to oxidative stress, reduced ischemic brain damage,
protection of neurons form stroke-induced damage and reversion of age-
related changes in brain and behaviour. Regarding the secondary
metabolites of berry fruits, anthocyanins count among the main
constituents. The present study addresses proteasome inhibition as a
possible mechanism by which anthocyanins and their aglycons, the
anthocyanidins, may exert health-promoting effects. Methods: HL-60
cells were incubated with test substances and inhibition of the
chymotrypsin-like enzyme activity was determined with a
chemiluminescent assay. Results: Anthocyanins and their aglycons
inhibited proteasome activity in a concentration-dependent manner and
achieved IC50 values ranging from 7.8µmol/L for kaempferidinidin and
pelargonidin, to 32.4µmol/L for delphinidin. Conclusions: Proteasome
inhibitory properties of anthocyanins may contribute to their known
anticarcinogenic, antioxidative, anti-inflammatory and neuroprotective
activities, rationalizing dietary supplementations with anthocyanins
in the prevention and treatment of cancer, stroke and
neurodegenerative diseases.
DOI: 10.1055/s-2007-1002801
Who loves ya.
Tom
ironj...@aol.com
wrote:anthocyanins <<
"Anthocyanins are potent antioxidants"
Chemical composition of strawberries and blueberries
Planta Med 2008; 74
E Sofic 1, 2, 4, A Uzunovic 2, K Durić 2, S Muradic 3, S Huseinovic 3,
J Toromanovic 1, N Lischner 4
1 Faculty of Science, University of Sarajevo, Zmaja od Bosne 33-35, 71
000 Sarajevo, Bosnia and Herzegovina
2 Faculty of Pharmacy, University of Sarajevo, Cekalusa 90, 71 000
Sarajevo, Bosnia and Herzegovina
3 Karl-Franzens University, Universitätsplatz 1, Graz, Austria
4 Jean Mayer Human Nutrition Research Center on Aging, Tufts
Universyity, Boston, (MA) USA
Objectives: Aim of this study was to determine chemical composition of
strawberries and blueberries. Methods: Reverse phase HPLC-ECD-
Couloarray system and HPLC-UV/VIS was used for determination of
chemical composition of strawberries and blueberries. Total phenolics
and anthocyanins was quantified using two spectrophotometric methods.
Results: Strawberries contain the highest percentage of water, 70mg/
100g f.w. ascorbic acid, 24µg/100g f. w. folic acid, catechin 10-70ng/
kg f.w., epicatechin 10mg/kg f.w., ellagic acid 12,5mg/g dry weight.
After hydrolysis of fruits were found: caffeic acid, 10mg/100g f.w.; p-
coumaric acid, 10-15mg/100g f.w.; 4-hydroxybenzoic acid, 10-35mg/100g
f.w.; protocatehuic acid, 6mg/100g f.w. and gallic acid, 10-40mg/100g
f.w. Strawberries contain 350mg/100g f.w. of total phenolics and 80mg/
100g f.w. of total anthocyanins. In bluberries are identified gallic,
homoprotocatechuic, chlorogenic, caffeic and syringic acid, rutin,
quercetin-3-glucoside, quercetin-3-arabinoside, phyloquinone (Vitamin
K1), Vitamin C and Vitamin E. Blueberries contained simple and
acylated anthocyanins and other phenolics. Mostly of anthocyanins in
blueberries are contained glucosides and galactosides of delphinidin,
cyanidin, peonidin and petunidin. Total anthocyanins in blueberries
ranged from 340mg/100g f.w. to 450mg/100g f.w. Total phenolics in
blueberries ranged from 980mg/100g to 1050mg/100g of fresh berries.
Conclusion: Chemical composition of strawberries and blueberries are
very complex. Flavonoids and anthocyanins are potent antioxidants and
may be neuroprotective and chemoprotective.
DOI: 10.1055/s-0028-1084853
Michael B
Short but articulate answer is preferred.
On Aug 20, 10:21 am, ironjustice <teamtan...@hotmail.com> wrote:
Paul T. Holland
"wrth...@ix.netcom.com" wrote:
>
>
> Has anyone figured out what he's saying in those URLs of his?
> I've looked at them, and despite the labels they have nothing to
> do with his imaginary childhood friends. Is he trying to sell
> biphosphonate, or whatever else he's fixated on? If so he can
> be turned in for commercial spam.
>
> --Bill Thompson
tom has never been associated with any personal commercial endeavors -
he is a 'true believer' in a cause
he styles himself as a self-taught 'expert' and compares his searching
the internet and reposting the works of others to actual original
research that others actually do.
claims that he deserves credit for, and is the instrumental catalyst
for, the research that professionals are doing.
i believe it fair to characterize it as a singular obsession.
Michael B
and lacks the capacity to read the info he has delivered to answer
questions answered within the material. So in spite of his calling
himself a "Health Research Analyst", he is no more of an analyst
than my daughter's hamster. That died a few years ago.
On Aug 24, 1:16 pm, "Paul T. Holland" <pholl...@bellatlantic.net>
wrote:
> tom has never been associated with any personal commercial endeavors -
Harvey R. Stone
"Michael B" <baug...@bellsouth.net> wrote in message
news:a43967e5-c871-4d2c...@m3g2000hsc.googlegroups.com...
OK,,,, ok,,,,, Knowing that,,,, accepting that,,,, The question is should
you spend time, bandwidth, space in this newsgroup in a discourse with this
person.... Questions,,,, what do you gain,,,, what is accomplished,,,,,
What does it do for you????? Please do not just brush my questions off.
I really would like an answer from both of you.
Harv
Michael B
first as a Biomedical Electronics Tech for a physiology and
biophysics department, then after getting my nursing degree
I was in a cardiac cath lab for nearly 15 years at a teaching
hospital. So in a way, his posts make me a bit wistful of the
days gone by, but not enough to go back to spending nights
in the oncall quarters with everyone else and their pagers
going off.
Indeed, the concept of oxidative stress is a valid one, for the
people that either cannot effectively deal with excess iron, or
other reasons. But it isn't like he is just now making the
medical community aware of it. He would be immediately
discounted by that community because he is clearly unable
to discern details from what he is hammering away at. Which
he sees as an excessive amount of iron accumulation due to
the failure to stop eating meat products with the iron they
carry.
But frankly, in spite of his lack of awareness of what he posts,
I frequently find things of value in the posts. Granted, he is an
idiot that somehow thinks presenting the entire text instead
of a simple URL is more professional. He seems completely
unable to hold one-on-one discussions about his speculations,
so instead of having simple one-liners and the URL , he sees
quantity to be a sufficient mask for his inadequacies. But every
once in a while, something shows up that is of interest.
Speaking of inadequate, he is also very obviously gender and
ethnicity-biased, as well as seeing anyone that questions his
posting style as being intellectually inferior and not worthy of
his time. He likely realizes that he is a mental midget, and
frequently demonstrates that as well. I wish he didn't have
so much disdain for pathophysiology, but it's just as well
since he has no clue anyway.
Your question was regarding what is accomplished by doing
something other than ignore him. There are those here, myself
included, for which he provides amusement. And indeed, there
are folks that do need their iron levels checked. Ditto for their
Vitamin D, their TSH, their prospect of Lyme, etc. He and 'his'
threads are easy enough to ignore, and the days of having to
pay by total message size are over. I allocate my break time
from projects, including proof-reading journal articles at the
galley-proof level, to extraneous stuff like seeing what drivel
he has come up with lately, or what journal articles he has
found that happen to mention iron or one of its variants.
Rather refreshing to not have to be cerebral all the time.
That, indeed, is likely to be the value I see in his posts.
Certainly, others may see things differently. That's really
okay with me. As you are likely aware, I have offered to
ignore his posts if he didn't include alt.med.fibromyalgia in
the crosspostings. The fact that he continues to include
AMF in his posts means that he sees value in being
reminded that he mainly provides amusement to his
audience, small that it is.
On Aug 24, 2:46 pm, "Harvey R. Stone" <hrst...@swbell.net> wrote:
> "Michael B" <baugh...@bellsouth.net> wrote in message
I M Portant
I M Portant
Unless it can be copied and pasted, you will not get an answer but just
the usual malarkey. Copy and paste and the his usual response takes no
thinking
I M Portant
Granted, he is an
> idiot that somehow thinks presenting the entire text instead
> of a simple URL is more professional. He seems completely
> unable to hold one-on-one discussions about his speculations,
> so instead of having simple one-liners and the URL , he sees
> quantity to be a sufficient mask for his inadequacies.
Yes, copy and paste takes little mental effort
>But every
> once in a while, something shows up that is of interest.
Do anything enough, and every now and then may be good - put an infinite
number of monkeys in a room randomly typing and will .....
I M Portant
Granted, he is an
> idiot that somehow thinks presenting the entire text instead
> of a simple URL is more professional. He seems completely
> unable to hold one-on-one discussions about his speculations,
> so instead of having simple one-liners and the URL , he sees
> quantity to be a sufficient mask for his inadequacies.
Yes, copy and paste takes little mental effort
>But every
> once in a while, something shows up that is of interest.
Do anything enough, and every now and then may be good - put an infinite
I M Portant
Granted, he is an
> idiot that somehow thinks presenting the entire text instead
> of a simple URL is more professional. He seems completely
> unable to hold one-on-one discussions about his speculations,
> so instead of having simple one-liners and the URL , he sees
> quantity to be a sufficient mask for his inadequacies.
Yes, copy and paste takes little mental effort
>But every
> once in a while, something shows up that is of interest.
Do anything enough, and every now and then may be good - put an infinite
ironjustice
Stay off my threads .. lefty .. like you've been TOLD ..
ironjustice
<<
More comments from mr .. useless .. oh sorry .. mr unimportant ..
ironjustice
mr unimportant <<
Can't contribute .. stay out of the .. way ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
.
Harvey R. Stone
From my perspective, I used to be in the medical business,
first as a Biomedical Electronics Tech for a physiology and
biophysics department, then after getting my nursing degree
From your answer,,,, laughing at a mental midget who can't help himself.
That says far more about you than about him.
Harv
Michael B
Everybody see how much he enjoys my being here?
So much so that I'll bet he will start a new thread tomorrow,
and say to himself "Hmmm, how best to get Michael B to
notice? Of course!! Put it on alt.med.fibromyalgia, so he can
continue to see how stupid I am".
On Aug 24, 6:31 pm, ironjustice <teamtan...@hotmail.com> wrote:
> On Aug 23, 8:24 pm, Michael B <baugh...@bellsouth.net> wrote: lefty <<
>
> Stay off my threads .. lefty .. like you've been TOLD ..
>
> Who loves ya.
> Tom
>
I M Portant
> On Aug 24, 1:34 pm, I M Portant <import...@important.com> wrote:snip
> <<
>
> More comments from mr .. useless .. oh sorry .. mr unimportant ..
>
Very lame attempt from your usual inane comments
I M Portant
> On Aug 24, 1:32 pm, I M Portant <import...@important.com> wrote:
> mr unimportant <<
>
>
> Can't contribute .. stay out of the .. way ..
>
Just copying and pasting is not what I call contributing much of
anything important. I never claimed to be trying to contribute and if I
did it would not just be as you do, but give a link to an article, a
summary and my interpretation
ironjustice
<<
Harvey .. you shtflldsknbag .. you've been told to stay off my
threads ..
Follow orders ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> "Michael B" <baugh...@bellsouth.net> wrote in message
ironjustice
Stay off my threads .. lefty .. like you've been TOLD ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk- Hide quoted text -
>
> - Show quoted text -
ironjustice
<<
mr. unimportant .. contributes .. ?
Nope ..
Surprise .. surprise ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
ironjustice
never claimed to be trying to contribute and if I
did it would not just be as you do, but give a link to an article, a
summary and my interpretation <<
YOUR .. 'opinion' .. is **noted**..
Now to attempt to force your .. opinion .. ON .. me .. is not a good
idea ..
Understand .. ?
Very .. good ..
Now the thread is .. anthocyanins ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
I M Portant
> On Aug 24, 4:59 pm, Michael B <baugh...@bellsouth.net> wrote: snip <<
>
> Stay off my threads .. lefty .. like you've been TOLD ..
>
Can you two iron out your differences?
I M Portant
> On Aug 24, 5:07 pm, I M Portant <import...@important.com> wrote: snip
> <<
>
> mr. unimportant .. contributes .. ?
>
> Nope ..
>
> Surprise .. surprise ..
>
No surprises from you.
I make no claim to contributing, but here to learn. Copying and pasting
articles is not really contributing as any fool can do that.
I M Portant
> On Aug 24, 5:12 pm, I M Portant <import...@important.com> wrote: I
> never claimed to be trying to contribute and if I
> did it would not just be as you do, but give a link to an article, a
> summary and my interpretation <<
>
> YOUR .. 'opinion' .. is **noted**..
>
> Now to attempt to force your .. opinion .. ON .. me .. is not a good
> idea ..
>
I am not wasting my time trying to convince you of anything - sorry to
disappoint you, but you are not the center of everyone's world except
your own
Realized fairly quickly that cannot change a rigid, stuck in a rut,
non-thinking, one track simple, non-reasoning mind like yours.
Paul T. Holland
to which he will likely reply - 'fe' on you!
Jim Carter
<phol...@bellatlantic.net> wrote:
> tom - as demonstrated by my previous message quoting definitions -
> multiple postings of the same information, article, or message in such a
> repetative manner IS considered spam
There is an increasing number of usenet users who consider Google to be the
source of much spam. The following is a sig line explaining what it is all
about.
"Killing all posts from Google Groups
The Usenet Improvement Project: http://improve-usenet.org
Need a new news feed? http://blinkynet.net/comp/newfeed.html"
More free newsgroups are opening up.
Paul T. Holland
"Harvey R. Stone" wrote:
> OK,,,, ok,,,,, Knowing that,,,, accepting that,,,, The question is should
> you spend time, bandwidth, space in this newsgroup in a discourse with this
> person.... Questions,,,, what do you gain,,,, what is accomplished,,,,,
> What does it do for you????? Please do not just brush my questions off.
> I really would like an answer from both of you.
>
> Harv
hi harv - actually, i'm not responding to much of his at all now -
i do feel an obligation to not let all the homophobic [and other] slurs
go unchallenged, and yes, i will occasionally chime in, as on the math
question.
but on a count basis, that is only a small portion of his total
i answered his assertion about the meaning of spam with actual
definitions - that he ignores - ah well
this last one was an honest query from a stranger - i think my response
was measured.
and yes, i do think folk should forward any clearly abusive posts if
they are so inclined.
hopefully, volume will abate in the near future, history indicates it's
about run it's course.
I M Portant
A new version:
Fe! Fie! Foe! Fum!
I smell the blood of an Englishman.
Be he 'live, or be he dead,
I'll grind his bones to make my iron-rich bread.
ironjustice
<<
What part of useless .. don't you understand .. there ..
unimportant ..?
You don't contribute .. and sooo .. what are you doing on this
thread .. ?
Eh ..
Stay off the thread ..
Understand .. ?
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
ironjustice
<<
Stay off the thread .. you don't contribute soooo .. you got a reason
to be .. here .. do ya ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> ironjustice wrote:
ironjustice
<<
Stay off the thread ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> ironjustice wrote:
ironjustice
wrote: long winded whack <<
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> > Can you two iron out your differences?- Hide quoted text -
Cheeky Bastard
"ironjustice" <teamt...@hotmail.com> wrote in message
news:dc548444-7f69-4b0e...@34g2000hsh.googlegroups.com...
On Aug 20, 7:30 pm, Michael B <baugh...@bellsouth.net> wrote:snip <<
Lefty .. what were you told to do ...
YOU were told to leave many times, did you comply?
Nuff said
CB
ironjustice
Stay off my threads .. useless twit ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> Paul T. Holland wrote:
> > lolol
>
> > to which he will likely reply - 'fe' on you!
>
> > I M Portant wrote:
> >> ironjustice wrote:
> >>> On Aug 24, 4:59 pm, Michael B <baugh...@bellsouth.net> wrote: snip <<
>
Cheeky Bastard
At Least we don't have to haul his trash to the curb. We just delete.
CB
"Paul T. Holland" <phol...@bellatlantic.net> wrote in message
news:48ADCBC9...@bellatlantic.net...
> tom - as demonstrated by my previous message quoting definitions -
> multiple postings of the same information, article, or message in such a
> repetative manner IS considered spam
>
>
> ironjustice wrote:
>>
>> On Aug 21, 3:17 am, Michael B <baugh...@bellsouth.net> wrote:snip <<
>>
>> Lefty .. what were you told to do ...
>>
>> Effects of Anthocyanins on Psychological Stress-Induced Oxidative
>> Stress and Neurotransmitter Status
>> J. Agric. Food Chem., 56 (16), 7545-7550, 2008.
>> Effects of Anthocyanins on Psychological Stress-Induced Oxidative
>> Stress and Neurotransmitter Status
>> M. Mamunur Rahman,? Takashi Ichiyanagi,? Tadazumi Komiyama,? Shinji
>> Sato,? and Tetsuya Konishi*?
>> Faculty of Applied Life Sciences, Faculty of Pharmaceutical Sciences,
>> Niigata University of Pharmacy and Applied Life Sciences, 265-1
>> Higashijima, Niigata 956-8603, Japan
>> Received for review March 26, 2008. Revised manuscript received May
>> 26, 2008. Accepted June 23, 2008. This study was supported in part by
>> a Grant in Aid from AOA Japan Co., LTD., and also from the Uchida
>> Science Promotion Foundation, Niigata, Japan.
>> Abstract:
>> There is strong evidence that oxidative stress participates in the
>> etiology of neurodegenerative diseases such as Parkinson's, and
>> Alzheimer's diseases.
>> Moreover, emotional stress effects in the central nervous system play
>> a vital role in homeostasis.
>> The protective effect of anthocyanins on the cerebral oxidative
>> stress
>> was studied using the whiskers cut model.
>> In mice, such treatment causes psychological or emotional distress
>> leading to oxidative stress in tissues.
>> To investigate the in vivo antioxidant activity of anthocyanins, an
>> extract of Vaccinium myrtillis L., an anthocyanin mixture, was orally
>> administered (100 mg/kg of body weight.) to mice for 7 days, and then
>> psychological stress was assessed by cutting off their whiskers.
>> Whisker removal increased both protein carbonyl formation and lipid
>> peroxidation in the brain, heart, kidney, and liver.
>> Further, the levels of oxidative markers showed regional differences
>> in the brain.
>> Concomitantly, dopamine neurotransmitter levels were altered in both
>> the midbrain and the brain cortex.
>> Orally administered anthocyanins were also active in the brain,
>> suppressing stress-induced cerebral oxidative stress and dopamine
>> abnormalities in distressed mice.
>> These effects of anthocyanin treatment suggest their possible
>> usefulness for the treatment of cerebral disorders related to
>> oxidative stress.
>> Keywords: Anthocyanin; antioxidant activity; psychological stress;
>> dopamine.
>> 10.1021/jf800930s
>> Web Release Date: July 29, 2008
>> Copyright © 2008 American Chemical Society
>> --------------------
>> http://www.chiro.org/nutrition/FULL/Anthocyanins.shtml
>>
>> From the December 2001 Issue of Nutrition Science News
>> By Marilyn Sterling, R.D.
>>
>> These plant pigments are more than coloring agents for fruit juices,
>> wine, and other beverages. They also contain an array of health-
>> promoting benefits.
>> Eaten in large amounts by primitive humans, anthocyanins are
>> antioxidant flavonoids that protect many body systems.
>> They have some of the strongest physiological effects of any plant
>> compounds, and they are also things of beauty: anthocyanins provide
>> pigment for pansies, petunias, and plums. (Anthocyanins are a
>> separate
>> class of flavonoids from proanthocyanidins, discussed in NSN
>> 2000;5(6):
>> 231-4.)
Cheeky Bastard
"I M Portant" <impo...@important.com> wrote in message
news:pNmsk.7293$lU5....@newsread1.mlpsca01.us.to.verio.net...
I just wonder when the day will come and he has ONE intelligent thought of
HIS OWN to post.
Ofcourse the minute somebody replies he will attack.
CB
Cheeky Bastard
>
>
> "wrth...@ix.netcom.com" wrote:
>>
>
>>
>> Has anyone figured out what he's saying in those URLs of his?
>> I've looked at them, and despite the labels they have nothing to
>> do with his imaginary childhood friends. Is he trying to sell
>> biphosphonate, or whatever else he's fixated on? If so he can
>> be turned in for commercial spam.
>>
>> --Bill Thompson
>
> tom has never been associated with any personal commercial endeavors -
> he is a 'true believer' in a cause
>
> he styles himself as a self-taught 'expert' and compares his searching
> the internet and reposting the works of others to actual original
> research that others actually do.
>
> claims that he deserves credit for, and is the instrumental catalyst
> for, the research that professionals are doing.
>
> i believe it fair to characterize it as a singular obsession.
Paul more proof search engines can be evil. Without them idiots like him
would be stuck.
CB
ironjustice
snip <<
Stay off my threads ..
You are consistently nonsupportive and noncontributory ..
Either one of the above is .. **mandatory** understand .. ?
Don't come back until you FULLY understand the meaning of the word ..
mandatory.
Understand .. ?
Goooood ..
I M Portant
> On Aug 25, 1:08 pm, I M Portant <import...@important.com> wrote: snip
> <<
>
> Stay off the thread .. you don't contribute soooo .. you got a reason
> to be .. here .. do ya ..
Once posted,it is no longer your thread even though what you do is a
mindless copying and pasting.
Hardly call what you do as contributing.
I M Portant
> On Aug 25, 1:07 pm, I M Portant <import...@important.com> wrote:snip
> <<
>
> What part of useless .. don't you understand .. there ..
> unimportant ..?
>
> You don't contribute .. and sooo .. what are you doing on this
> thread .. ?
>
What part of useless that simply copying and pasting an article is of
little value do not **you** not understand.
I M Portant
> On Aug 25, 1:12 pm, I M Portant <import...@important.com> wrote: snip
> <<
>
> Stay off the thread ..
>
Once posted, anyone can add to it, criticize it or change the direction.
If you cannot understand that, then that may explain why you can
only copy and paste.
I M Portant
> On Aug 25, 2:44 pm, I M Portant <import...@important.com> wrote:
>
> Stay off my threads .. useless twit ..
>
Your use of pejorative terms is a poor substitute for an adult answer.
But, it is what you do and who you are.
ironjustice
come back until you FULLY understand the meaning of the word ..
mandatory.
Understand .. ?
Goooood ..
ironjustice
mandatory.
Understand .. ?
Goooood ..
ironjustice
mandatory.
Understand .. ?
Goooood ..
Michael B
Hey, Rusty.
I know for fact that YOU do not comprehend oxidative stress.
Understand?
Gooood..
ironj...@aol.com
Lefty .. you were told to stay off my posts ..
Who loves ya.
Tom
ironj...@aol.com
oxidative stress <<
http://tinyurl.com/68hoj4
Very few individuals, if any, reach their potential maximum life span;
they die instead prematurely of a wide variety of diseases--the vast
majority being "free radical" diseases.
--Denham Harmon, M.D., Ph.D., who in 1954 first proposed the Free
Radical Theory of aging
Great moments in human history often begin inauspiciously. Such was
the case in December 1945, when the wife of Denham Harmon handed him
the latest issue of the Ladies' Home Journal. It was opened to an
article titled "Tomorrow You May Be Younger," written by William L.
Laurence, science editor of the New York Times. This article,
heralding the work of a Russian gerontologist on an "anti-reticular
cytotoxic serum," sparked Dr. Harmon's interest in finding an answer
to the riddle of aging--a subject that scientists of the time knew
absolutely nothing about.
For the next nine years, Dr. Harmon, a brilliant young organic chemist
with a Ph.D. from the University of California, Berkeley, ruminated
about the aging process. Because aging is such a universal phenomenon,
he reasoned that it might have a single basic cause. But what could it
be? The answer eluded him.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> Don't come back until you FULLY understand the meaning of the word ..
> mandatory.
>
> Understand .. ?
>
> Goooood ..
>
> Who loves ya.
> Tom
>
Cheeky Bastard
you posted!
That will get your panties in a knot if you understand the article. LOL
CB
"ironjustice" <teamt...@hotmail.com> wrote in message
news:34a2aaf2-ff8c-4e4b...@59g2000hsb.googlegroups.com...
Cheeky Bastard
"I M Portant" <impo...@important.com> wrote in message
news:FhEsk.7302$lU5....@newsread1.mlpsca01.us.to.verio.net...
> ironjustice wrote:
>> On Aug 24, 4:59 pm, Michael B <baugh...@bellsouth.net> wrote: snip <<
>>
>> Stay off my threads .. lefty .. like you've been TOLD ..
Cheeky Bastard
wanted any advice he THOUGHT he could offer.
PS Tommy stick it up your butt THIS IS MY THREAD lol
"I M Portant" <impo...@important.com> wrote in message
news:KhKsk.7306$lU5....@newsread1.mlpsca01.us.to.verio.net...
I M Portant
> On Aug 25, 8:18 pm, Michael B <baugh...@bellsouth.net> wrote: snip <<
>
> Lefty .. you were told to stay off my posts ..
>
>
I do not think he is going to do as you want .... perhaps, because once
posted, they become in the public domain of these groups - do you
understand public domain.
"Don't come back until you FULLY understand the meaning of the" term ..
public domain.
I M Portant
ironj...@aol.com
ironj...@aol.com
ironj...@aol.com
off the thread .. you don't contribute soooo .. you got a reason
ironj...@aol.com
Cheeky Bastard
OPEN WIDE!
"ironjustice" <teamt...@hotmail.com> wrote in message
news:6067d069-7902-40b0...@k7g2000hsd.googlegroups.com...
Cheeky Bastard
<ironj...@aol.com> wrote in message
news:9baaae3d-2c98-477e...@z66g2000hsc.googlegroups.com...
Cheeky Bastard
CB
"I M Portant" <impo...@important.com> wrote in message
news:1jLsk.7315$lU5...@newsread1.mlpsca01.us.to.verio.net...
Cheeky Bastard
I just pissed in it.
CB
<ironj...@aol.com> wrote in message
news:14176917-e49d-4422...@l42g2000hsc.googlegroups.com...
ironjustice
wrote:Stay
off the thread .. you don't contribute soooo .. you got a reason
ironjustice
Cheeky Bastard
"ironjustice" <ironj...@aol.com> wrote in message
news:62ea4764-35cc-43d7...@d45g2000hsc.googlegroups.com...
ironjustice
snip <<
You realllly .. represent .. very well .. you knowww .. that .. ?
Heh .. heh ..
English nancies
Go feed your .. gerbil ..
Cheeky Bastard
"ironjustice" <ironj...@aol.com> wrote in message
news:a11359a8-dd8f-4bb8...@x35g2000hsb.googlegroups.com...
ironjustice
snip <<
Describe yourself for everyone ..
Be .. like .. sorta .. manlish ..
I'll see if we can't turn .. ya .. back ..
Eh .. nancie ..
You would like to see what being .. normal .. is .. ?
Ramp up the ole testosterone .. grow you some .. cojones .. eh ..
Michael B
what he studies right after having sent a bunch of stuff he can't
explain but has some words he recognizes. After all, his pubic
domain is something he likely does understand.
Oh, silly me. I misread your words!! You said public, with an "L".
Never mind.
ironjustice
Lefty .. you were told to stay off my posts ..
Who loves ya.
I M Portant
> On Aug 26, 3:45 am, Michael B <baugh...@bellsouth.net> wrote:
> snip
> <<
>
> Lefty .. you were told to stay off my posts ..
>
Duh - it is really not surprising why you persist in saying the same
thing over and over and not realizing that he, and most others, are not
doing as you write - can you understand that?
ironjustice
<<
Fruitcake .. you were told to .. hit .. the .. road ..
I M Portant
> On Aug 26, 6:22 am, I M Portant <import...@important.com> wrote: snip
> <<
>
> Fruitcake .. you were told to .. hit .. the .. road ..
>
>
Maybe no one does as you write because what you write is worthless. You
should try to advance a little beyond elementary schoolyard taunts -
unless you are unable to do that.
ironjustice
> <<
> Fruitcake .. you were told to .. hit .. the .. road ..
Paul T. Holland
fortune...
Cheeky Bastard wrote:
>
> "Paul T. Holland" <phol...@bellatlantic.net> wrote in message
> news:48B19767...@bellatlantic.net...
> >
> >
> > "wrth...@ix.netcom.com" wrote:
> >>
> >
> >>
> >> Has anyone figured out what he's saying in those URLs of his?
> >> I've looked at them, and despite the labels they have nothing to
> >> do with his imaginary childhood friends. Is he trying to sell
> >> biphosphonate, or whatever else he's fixated on? If so he can
> >> be turned in for commercial spam.
> >>
> >> --Bill Thompson
> >
> > tom has never been associated with any personal commercial endeavors -
> > he is a 'true believer' in a cause
> >
> > he styles himself as a self-taught 'expert' and compares his searching
> > the internet and reposting the works of others to actual original
> > research that others actually do.
> >
> > claims that he deserves credit for, and is the instrumental catalyst
> > for, the research that professionals are doing.
> >
> > i believe it fair to characterize it as a singular obsession.
>
> Paul more proof search engines can be evil. Without them idiots like him
> would be stuck.
>
> CB
Paul T. Holland
trees?
Cheeky Bastard wrote:
>
> Ya'but Paul,
>
> At Least we don't have to haul his trash to the curb. We just delete.
>
> CB
> "Paul T. Holland" <phol...@bellatlantic.net> wrote in message
> news:48ADCBC9...@bellatlantic.net...
> > tom - as demonstrated by my previous message quoting definitions -
> > multiple postings of the same information, article, or message in such a
> > repetative manner IS considered spam
> >
> >
> > ironjustice wrote:
> >>
> >> On Aug 21, 3:17 am, Michael B <baugh...@bellsouth.net> wrote:snip <<
> >>
> >> Lefty .. what were you told to do ...
> >>
> >> Effects of Anthocyanins on Psychological Stress-Induced Oxidative
> >> Stress and Neurotransmitter Status
> >> J. Agric. Food Chem., 56 (16), 7545-7550, 2008.
> >> Effects of Anthocyanins on Psychological Stress-Induced Oxidative
> >> Stress and Neurotransmitter Status
> >> M. Mamunur Rahman,? Takashi Ichiyanagi,? Tadazumi Komiyama,? Shinji
> >> Sato,? and Tetsuya Konishi*?
> >> Faculty of Applied Life Sciences, Faculty of Pharmaceutical Sciences,
> >> Niigata University of Pharmacy and Applied Life Sciences, 265-1
> >> Higashijima, Niigata 956-8603, Japan
> >> Received for review March 26, 2008. Revised manuscript received May
> >> 26, 2008. Accepted June 23, 2008. This study was supported in part by
> >> a Grant in Aid from AOA Japan Co., LTD., and also from the Uchida
> >> Science Promotion Foundation, Niigata, Japan.
> >> Abstract:
> >> There is strong evidence that oxidative stress participates in the
> >> etiology of neurodegenerative diseases such as Parkinson's, and
> >> Alzheimer's diseases.
> >> Moreover, emotional stress effects in the central nervous system play
> >> a vital role in homeostasis.
> >> The protective effect of anthocyanins on the cerebral oxidative
> >> stress
> >> was studied using the whiskers cut model.
> >> In mice, such treatment causes psychological or emotional distress
> >> leading to oxidative stress in tissues.
> >> To investigate the in vivo antioxidant activity of anthocyanins, an
> >> extract of Vaccinium myrtillis L., an anthocyanin mixture, was orally
> >> administered (100 mg/kg of body weight.) to mice for 7 days, and then
> >> psychological stress was assessed by cutting off their whiskers.
> >> Whisker removal increased both protein carbonyl formation and lipid
> >> peroxidation in the brain, heart, kidney, and liver.
> >> Further, the levels of oxidative markers showed regional differences
> >> in the brain.
> >> Concomitantly, dopamine neurotransmitter levels were altered in both
> >> the midbrain and the brain cortex.
> >> Orally administered anthocyanins were also active in the brain,
> >> suppressing stress-induced cerebral oxidative stress and dopamine
> >> abnormalities in distressed mice.
> >> These effects of anthocyanin treatment suggest their possible
> >> usefulness for the treatment of cerebral disorders related to
> >> oxidative stress.
> >> Keywords: Anthocyanin; antioxidant activity; psychological stress;
> >> dopamine.
> >> 10.1021/jf800930s
> >> Web Release Date: July 29, 2008
> >> Copyright © 2008 American Chemical Society
> >> --------------------
> >> http://www.chiro.org/nutrition/FULL/Anthocyanins.shtml
> >>
> >> From the December 2001 Issue of Nutrition Science News
> >> By Marilyn Sterling, R.D.
> >>
> >> These plant pigments are more than coloring agents for fruit juices,
> >> wine, and other beverages. They also contain an array of health-
> >> promoting benefits.
> >> Eaten in large amounts by primitive humans, anthocyanins are
> >> antioxidant flavonoids that protect many body systems.
> >> They have some of the strongest physiological effects of any plant
> >> compounds, and they are also things of beauty: anthocyanins provide
> >> pigment for pansies, petunias, and plums. (Anthocyanins are a
> >> separate
> >> class of flavonoids from proanthocyanidins, discussed in NSN
> >> 2000;5(6):
> >> 231-4.)
Paul T. Holland
high road tommy
play nice, or it won't stop...
I M Portant
> no one wants to be on 'your' low road - that is why we all stay on the
> high road tommy
>
> play nice, or it won't stop...
>
He is more in the gutter on the low road.
From his use of elementary schoolyard taunts, I do not think he has
matured enough to play as an adult
Michael B
way he can get the attention. (Other than rather personal
attention when he moves away from the keyboard, or types
with one hand).
On Aug 26, 3:06 pm, "Paul T. Holland" <pholl...@bellatlantic.net>
wrote:
Paul T. Holland
I M Portant wrote:
>
> Paul T. Holland wrote:
> > no one wants to be on 'your' low road - that is why we all stay on the
> > high road tommy
> >
> > play nice, or it won't stop...
> >
>
> He is more in the gutter on the low road.
so why does 'snipe' come to mind? <g>
>
> From his use of elementary schoolyard taunts, I do not think he has
> matured enough to play as an adult
yet, when i call him 'kid', he objects - ah well