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Re: how mixing antihistamines with opiates can get you even higher (was: Re: Methadone Potentiators)

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Rob Cypher

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Sep 4, 2009, 8:04:18 PM9/4/09
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On Fri, 4 Sep 2009 13:56:41 -0700 (PDT), Freek <freek...@googlemail.com>
wrote:

>On 4 Sep, 20:04, jemida <jem...@sdf.lonestar.org> wrote:
>> A mate of mine used to hit up a few crushed cyclazine tablets with a 50 ml
>> meth amp or 2 �, i never tried it myself but it used to send him to
>> another planet .. i remember him telling me how when he was on it once,
>> the people he wa talking to who weren't there startyed telling him he was
>> crazy for talking to some other people who weren't there, he was alone all
>> the while .. i thought that was quite funny .. i wouldn't adviose trying
>> it without checking it out further tho coz its a pretty wild ride i think
>> ..
>>
>> -0
>
>Hi Jemidy, cyclizine has certain properties who make it added to a
>substance like methadone deliver ehh lets say being on another planet
>feeling whatever that could be, but to be a bit more exact a substance
>called dipipanone combined with cyclizine, its a methadone related
>molecule talking dipipanone the combo is sold having the brandname
>diconal mainly in the UK, delivers the best rush known to man, however
>that must depend on taste only its mentioned often so i dont doubt
>this one has certain interesting properties taken IV.
>Its not or just extremely rare prescribed talking diconal i never
>tried it, but when i say that i never considered a heroin rush as that
>much so not worth to destroy my veins then i am likely not the right
>person to judge diconal i just repeat what i read.
>Cyclizine is not a substance who can extend methadone's action it can
>only exhance the rush methadone delivers, but i dont have to tell you
>that this would make this matter only more addictive right.
>For those who feel like trying this combo i would recommend to take a
>bit less then the used to IV' d amount of methadone only and adding
>30-50 mg cyclizine more of that would not make a real difference, go
>ease on the ' done, do not try this if you never used ' done if you
>like to live some more.
>Regards, Freek.

I noticed this a long time ago with people mixing Talwin with a similar
old-school antihistamine. Apparently mixing (older H1) antihistamines
with various opiates has this effect.

No, none of the US OTC antihistamines (diphenhydramine or medicine) can do this
as far as I know. Promethazine may or may not do this...its often added to
codeine cough syrups here by pharmaceutical companies, so obviously they're
aware of the potential of mixing certain antihistamines with opiates.

Before you guys go trolling for Promethazine, remember that it is a very
weak relative of thorazine (some antihistamines also have antipsychotic
properties, with all the side effects that typically accompany such a drug).
Plus these types of antihistamine/antipsychotic tend to have a "paradoxical"
reaction in quite a few people...you get real anxious and have this feeling of
intense restlessness (I ran into this a few years ago when an ER used a similar
first generation H1 inverse agonist on me to control some nausea I had...can't
recall the name of it at the moment).

Vistaril (hydroxyzine), a commonly used antihistamine in America, is sometimes
mixed with codeine to improve the latter's performance.

You guys should be really trying not to do any of this, though. You should make
your family happy and be opiate free forever.

Rob Cypher
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Sep 6, 2009, 2:11:45 PM9/6/09
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On Sep 4, 5:04 pm, Rob Cypher <bals...@aol.com> wrote:
> On Fri, 4 Sep 2009 13:56:41 -0700 (PDT), Freek <freek123...@googlemail.com>
> Rob Cypherhttp://robcypher.livejournal.comhttp://www.myspace.com/robcyphercollectivehttp://www.facebook.com/robcypherhttp://www.youtube.com/robcypherhttp://www.twitter.com/robcypher
> Permabanned from the Dextroverse and Bluelight- Hide quoted text -
>
> - Show quoted text -

They certainly do a great job of enhancing my morphine buzz when I do
take them with my two Kadian SR 60mg capsules. You should check out
what happens when you mix the Kadian SR with histamines.

WOMP WOMP
Tom

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