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Jan 23, 2011, 9:07:25 AM1/23/11
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Computer algorithm, MRI used to tap memory
by Elizabeth Armstrong Moore


A computer algorithm, functional Magnetic Resonance Imaging (fMRI), and
neuroscientists working together have been able to identify what people
are remembering by measuring blood flow levels, according to new
research out of the University College London.

First, a group of 10 volunteers (average age 21) was shown three very
short (as in 7 seconds) films, each of a woman on a city street doing a
simple task, such as mailing a letter. Then, each of the volunteers was
placed inside an fMRI scanner and asked to recall each film, first in a
specific order, then at random.

One of the three short films showed this woman mailing a letter.
(Credit: Wellcome Trust Centre for Neuroimaging/UCL)

Using the scanner to measure changes in the brain's blood flow and a
computer algorithm, researchers were able to identify which short film
each person was remembering at a level the study's lead author describes
in a news release to be "significantly above what would be expected by
chance."

"This suggests that our memories are recorded in a regular pattern,"
says Martin Chadwick, who conducted the research at the University
College London's Wellcome Trust Centre for Neuroimaging. The article
appears in the journal Current Biology.

The researchers homed in on the medial temporal lobe, a region of the
brain thought to be most involved in episodic memory. The computer
algorithm performed best when analyzing the hippocampus, which the team
has already studied.

Across all participants, the rear right, front left, and front right
areas of the hippocampus appeared to be consistently involved. While it
remains unclear exactly what role the front two regions play, the rear
right was found in a previous study--identifying where a person was
standing in a virtual reality simulation--to be where spatial
information is recorded.

"Now that we are developing a clearer picture of how our memories are
stored, we hope to examine how they are affected by time, the aging
process and by brain injury," says Eleanor Maguire, who helmed the study
as an extension of last year's work on spatial memory.

It's arguable whether the algorithm's accuracy is good enough to
celebrate, since it identified the film being thought about correctly
less than half of the time (40 to 45 percent, to be precise). But that
is better than 33 percent, which is the rate at which a blind guess
between three films would be accurate.

Probably the most exciting discovery is that the memory traces
associated with each film were consistent throughout not only the study,
but from one volunteer to the next, suggesting that memories may in fact
have some sort of fixed, identifiable pattern.

http://news.cnet.com/8301-27083_3-10467801-247.html


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