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5-MeO-DMT is called “the God Molecule” for a simple and yet astounding reason: It can make one feel as if they are speaking to, connected with, or becoming one with the divine. Like many other psychedelics, 5-MeO-DMT is an entheogen. An entheogen is a chemical compound that can trigger mystical experiences—feelings of intense spirituality.
But you need not be religious or spiritual to have an entheogenic experience with 5-MeO-DMT (or any psychedelic for that matter). Every person’s individual experience is unique, and “God” is merely one word to describe the connectionthat the drug seems to make possible. Instead of “God,” others may prefer terms like Brahman, Nirvana, Gaia, Nature, Universal Consciousness, Higher Power, or none at all. Whatever term they use, each person’s experience is ultimately different, and the meaning and interpretation of that experience is up to the individual.
The idea that spirituality can be chemically triggered is one that many may find uncomfortable. But, as scientists probe into the mysterious world of psychedelics, many studies are finding exactly that: Psychedelics can inspire intense mystical experiences, similar to spontaneous religious epiphanies and spiritual revelations. Like religious or spiritual epiphanies, these chemically-induced experiences can be life-changing—and often correlate with the magnitude of healing the subject may experience for whatever indication they are aiming to treat with the psychedelic.
Indeed, some of the core tenants of a mystical experience include a deep-rooted feeling of unity and interconnectedness with the world around you, as well as profound feelings of joy, transcendence of time and space, and feelings of importance beyond the scope of the self. Psychedelic mystical experiences can be particularly profound because they can inspire a sense that this interconnectedness is reality, that this experience is the natural state of the world—the experience can have an inherent truth that extends beyond what words can describe.
In 2011, researchers used psilocybin to test the long-term impact of psychedelic therapy on personality changes in adults; psilocybin is the active constituent in magic mushrooms (sometimes simply called shrooms). In general, personality is considered relatively set after adults reach the age of 30. But, in this particular study, researchers found that psilocybin could inspire “lasting personality changes” for over a year after treatment.
And these changes were positive. After high-dose psilocybin therapy, participants who achieved a “mystical experience”—defined by specific criteria put forth by psychedelic scientists—left the study with higher marks of openness than they had upon arrival. “Openness” consists of a collection of personality traits, that includes a willingness to try new experiences, tolerance of others’ viewpoints, the appreciation of aesthetic qualities, and more.
Other studies found that psychedelic experiences have reduced depression and anxiety, aided in trauma therapy for post-traumatic stress, and even had positive impacts in reducing alcoholic addictions and obsessive-compulsive tendencies. But, the majority of these studies were performed on more common psychedelics, like psilocybin, lysergic acid diethylamide (LSD), and ketamine.
Now, researchers are testing the ability of 5-MeO-DMT to occasion similar results—and they’ve had small successes thus far. Recently, scientists proved that the toad molecule indeed can inspire mystical experiences, and may even hold potential as a more manageable therapy tool than psilocybin and LSD.
Of course, not every person will have such an awe-inspiring interaction with the drug. It’s even possible to have a challenging experience—one that’s uncomfortable, traumatizing, and even unsafe. Unlike your average medicine, there is no regulation nor substantive clinical research that provide guidance about how to use 5-MeO-DMT, while scientists also have not extensively looked into whether or not certain people may face considerable physical and mental health risks when trying the compound.
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