Hi Matthew, I'm running Windows 10 on a laptop which isn't as good as your system by the sounds of it and Meshroom working fine so far. I just unzipped the Meshroom-2018.1.0 folder and open the Meshroom.exe file by double clicking on it or RMB > open etc. Runs fine. In the downloaded folder you should have the following files: COPYING.md, Meshroom.exe, meshroom_photogrammetry.exe, python36.dll along with the following folders: aliceVision, lib, qtPlugins. Hope this helps. Good luck.