hello
I work with DB2 on old iSeries v6r1 from IBM for a few now, and everything is fine using python 2.7 with pyodbc, with unix or windows 10 clients.
I was discovering your libs, and wonder if it's ok with my setup, and the answer is YES, at least on windows.
So, if you have a working ODBC install, you just have to adjust your dsn from the basic example, and you're all set!
for info, my working dsn:
'DRIVER=iSeries Access ODBC Driver; SYSTEM=db_host; UID=user; PWD=password; DBQ=default_lib; EXTCOLINFO=1; Charset=utf-8'
some included options may not be needed, depending on your settings.
I don't test it yet on unix, since my setup don't provide python 3.5, but since I transpose my windows py2.7/pyodbc to py3.5/aioodbc flawlessly, I can't see why it should not work the same on unix.
if you have questions or comments, just let me know, I'll try to answer it.