Separately, version 5 and later will pop-up with a warning mesaage when a file is opened that is of a file format version later than the viewer. Note: PDF versions are 1.0 through 1.6; Acrobat/viewer versions are 1 through 7. A 1.6 file will trigger the warning in Reader 6.
Finally, Acrobat has settings to determine the file version at creation, and further editing can change the file version. In Acrobat 7, you can make a file PDF 1.5, and Reader 6 has no trouble. Open the file in Acrobat 7, make some changes, save it, and now it may be version 1.6 which Reader 6 will warn you about when opening.
Noah Katz