Are measures in UWNPSYCHSUM scaled by baseline measures?

[Adelyn Tsai]

Hi,

I want to ask for the composite scores in the UWNPSYCHSUM file, are they generated by scaling those measures by the baseline average and baseline standard deviation. That is, the measures from the follow-up visits can reflect how much change from the baseline.

Thank you again for your help,

Adelyn

[Danielle J Harvey]

My understanding is that the composite scores are computed separately for each visit (based on a model that was developed either using just baseline data or some longitudinal data). There is a methods document available for download on the ADNI website. There are also publications that go further into the details about how the composites were constructed (you should be able to access them through PubMed).

 

Danielle

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[Juliana Nery de Souza Talarico]

Hi,

I am looking for blood Abeta42 and Abeta40 for the ADNI1, GO, and 2 cohorts. I found it in the UPENN – 2D-UPLC and Bateman Lab datasets, but many participants did not have it. Is there another dataset in ADNI that contains blood Abeta42 and 40?

Thank you

Juliana

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[Danielle J Harvey]

Hi Juliana,

 

Plasma Abeta was not a planned part of ADNI-GO/2/3 – the plasma Abeta measures that are available are from side projects, so that is why the measures are not available for most participants. We will be collecting those measures as part of ADNI-4.

 

Danielle

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[Juliana Nery de Souza Talarico]

Em qua., 1 de mar. de 2023 às 9:50 AM, 'Danielle J Harvey' via Alzheimer's Disease Neuroimaging Initiative (ADNI) Data <adni...@googlegroups.com> escreveu:

Hi Juliana,

 

Plasma Abeta was not a planned part of ADNI-GO/2/3 – the plasma Abeta measures that are available are from side projects, so that is why the measures are not available for most participants. We will be collecting those measures as part of ADNI-4.

 

Danielle

 I got it! Thank you for the prompt answer.

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Juliana Nery de Souza-Talarico, PhD
Faculty member
Department of Medical Surgical Nursing
School of Nursing
University of São Paulo
Phone + 55 11 30617544
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