The IDA should only include scans that passed QC and were released from quarantine – MRIMPRANK should be a complete record of the ranking of all ADNI-1 scans that went to Mayo – are the visits of the scans that you are seeing in the IDA but not in MRIMPRANK after m36 or are they within ADNI-1? Are they all ADNI-1 participants (RID<2000)?
Danielle
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MRIMPRANK only includes information from the ADNI-1 visits (which for most folks is through m36, though there do appear to be m48 visits in there, but it may not capture all m48). It will not include anything for RIDs>2000, so no newly recruited ADNI-GO (or ADNI-2) participants will be in the file. For ADNI-1 folks, it won't include anything past m48.
Danielle
Hi Maryam,
Several files include the variable for series ID across all phases of ADNI (for example, in MPRAGEMETA the variable is SeriesID - the corresponding variable in the IDA_MR_Metadata_Listing file is LONIUID).
Danielle
"116_S_4453" in MPRAGEMETA, how can I find the ranking for them? |
Hi Maryam,
In ADNI-GO and ADNI-2, there we did a non-accelerated scan and an accelerated scan, so that is typically going to explain the 2 scans at a given visit for individuals with an RID>2000. In MPRAGEMETA with the variable Orig/Proc==”Original”, you will see a sequence descriptor MPRAGE for one of them and MPRAGE GRAPPA2 for the other (GRAPPA2 is the accelerated one). You will also see “Accelerated” in the Sequence Descriptors for IR-SPGR or IR-FSPGR. You can use SeriesID to identify the scan and then use ImageUID to identify the ID of either the original or the processed scan.
There shouldn’t be too many cases where there are “duplicates” not explained by accelerated vs non-accelerated (generally speaking, there should only be one processed scan for each accelerated and non-accelerated scan – and that is the preferred one, since Mayo only did the pre-processing on the preferred scan – I do think there are a few that slipped through, so there may be some that have more than one processed scan, but I’m not aware of how we can select the preferred one in those cases).
Danielle
Hi Maryam,
I believe the MRI Core generally recommended the GradWarp. As for instances where there is more than one processed scan (same sequence), yes, the larger UID is probably the preferred one...
Danielle
Hi Maryam,
The ADNI-1 study included a 3T MRI arm (so participants in that arm received both a 1.5T and 3T MRI). In ADNI-GO, the protocol (for newly recruited participants) was to scan at 3T (though continuing participants from ADNI-1 were continued at 1.5T unless there was a scanner change at the site). I'd potentially recommend using 1.5T since that was done on everyone in ADNI-1...
The lab that generated summary data using FreeSurfer processed both the 1.5T and 3T scans, so that data are available for both magnet strengths...
Danielle
"003_S_0908" |
"ADNI2 Initial Visit-Cont Pt" |
Hi Maryam,
I guess it depends on your research question. But, you will get more people if you stick to 1.5T in ADNI-1 (only ~25% of ADNI-1 participants received both 1.5T and 3T). If you see an ADNI-1 participant who has primarily 1.5T but then goes to 3T at some point and stays at 3T after that, that would likely be a scanner change. When I look at the person below (003_S_0908), I see 1.5T all the way through ADNI2 Year 1 Visit, but it switches to 3T for ADNI2 Year 2 Visit.