Clinical Immunology 6th Edition
Myra Krallman
Journal of Clinical Immunology is an international journal that focuses on human immunology, particularly primary immunodeficiencies and related diseases.
- Publishes high impact papers exploring diagnosis, pathogenesis, prognosis, or treatment of human diseases.
- Considers a wide range of studies, from genetic discovery and clinical description to immunologic assessment, diagnostic approach, prognosis evaluation, and treatment intervention.
- In the top 25% of qualifying journals for editorial excellence.
- High level of author satisfaction with 100% of authors reporting they would publish with us again.
- Case reports of general significance are also considered.
Essentials of Clinical Immunology provides the most up-to-date, core information required to understand diseases with an immunological basis. Clinically focussed, the sixth edition of this classic text presents theoretical and practical information in a simple yet thorough way.
Essentials of Clinical Immunology covers the underlying pathophysiology, the signs and symptoms of disease, the investigations required and guidance on the management of patients.
Perfect for clinical medical students, junior doctors and medical professionals seeking a refresher in the role of immunology in clinical medicine, this comprehensive text features fully updated clinical information, boxes with key points, real-life case histories to illustrate key concepts and an index of contents at the start of each chapter.
A companion website at www.immunologyclinic.com provides additional learning tools, including more case studies, interactive multiple-choice questions and answers, all of the photographs and illustrations from the book, links to useful websites, and a selection of review articles from the journal Clinical and Experimental Immunology.
This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.
Professor Helen Chapel, Consultant Immunologist and Professor of Clinical Immunology, John Radcliffe Hospital, University of Oxford. Course Director for the MSc in Integrated Immunology.
This second edition of a bestseller details the manifestations, diagnosis and treatment of immune-related disease in the dog and cat. It is illustrated throughout in full color, to show and explain to the reader as clearly as possible the complicated principles of disease and immunodiagnostic tests, supported by clinical cases, gross and histopathology, cytology, hematology, immunohistochemistry and other immunological tests.
Glossary
Basic Immunology
Immunopathological Mechanisms
The Basis of Immune-Mediated Disease
Immune-Mediated Haematological Disease
Immune-Mediated Skin Disease
Immune-Mediated Musculoskeletal and Neurological Disease
Immune-Mediated Alimentary Disease
Immune-Mediated Respiratory and Cardiac Disease
Immune-Mediated Endocrine Disease
Immune-Mediated Renal and Reproductive Disease
Immune-Mediated Ocular Disease
Immunodeficiency Disease
Immune System Neoplasia
Multisystem and Intercurrent Immune-Mediated Disease
Disease, of the Lymphoid Tissue
Immunotherapy
Vaccination
Further reading
Index
The nine members of the Clinical Immunology Committee are appointed by Council for staggered three-year terms. The role of the committee is to liaise with organizations and AAI committees dealing with clinical immunology.
The AAI Clinical Immunology Committee is dedicated to promoting research in the field of clinical immunology and addressing issues important to AAI member physician-scientists. The charges of the committee include:
The Medical Laboratory Immunology Fellowship at UNC Hospitals is a 2-year training program accredited by the Committee on Post-Doctoral Educational Programs of the American Society for Microbiology. The UNC program is one of only three accredited programs in the United States. The goal of this program is to provide training and experience in various aspects of medical laboratory immunology and prepare the trainee for board certification. Salary support for the fellow will be based upon the current departmental guidelines. Vacation and an annual fund for travel, books, etc. are provided and the amounts based upon the current departmental guidelines.
The fellow will gain hands on experience in performing various serologic methods for the detection of antibodies to bacterial, viral and parasitic pathogens. The fellow will gain experience in the clinical application of these tests by participation in infectious disease rounds, providing consultation to physicians on the selection and interpretation of tests, providing continuing education to laboratory and clinical staff and via didactic sessions with Dr. Schmitz.
Methodologies available for hands on training include ELISA, IFA, Western blot, agglutination, flocculation and instrumentation for ELISA plate handling as well as IFA slide processing. The following tests are currently performed by the Immunology Laboratory: HIV, HAV, HBV, HCV, EBV, Toxoplasma, CMV, HSV1/2, Syphilis, RMSF, Lyme. Additional tests that will be added in the next year include Ehrlichia.
The fellow will gain hands on experience in performing various serologic methods for the detection of antibodies to a variety of allergens and autoantigens utilized for the laboratory diagnosis of allergic and autoimmune diseases. The fellow will gain experience in the clinical application of these tests by participating in rounds and clinical conferences with rheumatology staff and to provide consultation to physicians on selection and interpretation of tests and provide continuing education to laboratory and clinical staff.
The fellow will gain hands on experience in performing flow cytometric immunophenotyping (lymphocyte subset enumeration, immunodeficiency diseases and leukemia/lymphoma phenotyping), and functional assays. Experience in evaluation of cellular immunologic function will also be obtained. The fellow will gain experience in the clinical application of these tests by participation in relevant rounds and clinical conferences and to provide consultation to physicians on selection and interpretation of tests and provide continuing education to laboratory and clinical staff.
The fellow will gain hands on experience in performing cytotoxicity and DNA based HLA typing and antibody screening/crossmatching methods including PCR, cytotoxicity, ELISA and flow cytometric based methods as well as cytotoxicity based crossmatch testing. The fellow will gain experience in the clinical application of these methods by participating in solid organ and bone marrow transplant rounds and clinical conferences and provide continuing education to laboratory and clinical staff.
The fellow will gain hands on experience in the performance of assays for quantitation of immunologlobulins, serum protein electrophoresis and immunofixation. In addition, this rotation will include training in DNA analysis for mutations associated with various inherited diseases and gene rearrangements.
Experience in laboratory management will be acquired in an ongoing fashion during the 2-year fellowship by interaction with laboratory technical and supervisory and administrative staff. In addition, didactic lectures and discussions pertaining to laboratory safety, accreditation, personnel management, quality control/assurance will be attended by the fellow.
After sufficient training and documentation of competency, the fellow will participate in the on-call rotation for the serology and cellular immunology laboratories. This will include performance of STAT tests after hours, organ donor infectious disease serologic testing, leukemia/lymphoma phenotyping and consultation for clinical and laboratory staff.
The fellow will be expected to design, conduct and submit for publication, studies relevant to medical laboratory immunology. These may include but are not limited to commercial test evaluation, new method development, clinical outcome studies. Opportunities for collaboration with other investigators are possible. It is also expected that the fellow attends and presents data at national meetings related to medical laboratory immunology.
The fellow will be expected to present continuing education lectures to immunology and other hospital laboratory staff. In addition, 2 cases per year will be presented the Pathology Residents Report. Throughout the 2 years of training, cases will also be presented at the weekly laboratory rounds and other conferences as needed. The fellow will also participate in teaching the first-year medical student immunology laboratory section.
The fellows may freely use the Health Affairs Library which is located adjacent to the hospital. There also are numerous computer workstations available in the library with internet access available to the Fellow. The fellows have free access to electronic journals and have their own computer work station in the fellows office. The internationally recognized UNC School of Public Health is located across the street from the UNC Hospitals. The fellows are encouraged to attend conferences and seminars of interest there.
We provide comprehensive care in allergic and immunologic disorders. The common allergic and immunologic conditions that we treat include allergic rhinitis, various subtypes of asthma including allergic bronchopulmonary aspergillosis and aspirin/NSAID sensitive asthma (also known as aspirin-exacerbated respiratory disease-AERD), chronic sinusitis, nasal polyps, drug allergy, food allergy, atopic dermatitis (eczema), urticaria, angioedema (histaminergic and kininergic/complement mediated), anaphylaxis, mast cell disorders such as mastocytosis and mast cell activation syndrome, eosinophilic disorders such as Churg-Strauss syndrome, and hypereosinophilic syndrome, and immunodeficiency conditions such as common variable immunodeficiency (CVID), IgA deficiency, and hyper IgE syndrome. We are a specialized referral center for the foregoing illnesses. Our patients are typically referred by their local doctors/specialists because of difficulty in diagnosing or treating the disease.
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