Fwd: What's new for ' Actualización TEM' in PubMed
riki BELDA
Ricardo Belda Lozano
Inicio del mensaje reenviado:
De: My NCBI <efb...@mail.nih.gov>
Fecha: 1 de octubre de 2014 12:30:54 GMT+2
Para: <riki...@hotmail.com>
Asunto: What's new for ' Actualizaci??n TEM' in PubMed
Responder a: <riki...@hotmail.com>
This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM).
Do not reply directly to this message.Sender's message: Nueva Bibliografía del TEM
Sent on Wednesday, 2014 October 01
Search: "Rectum"[Mesh] OR "Rectal Neoplasms"[Mesh] AND "Microsurgery"[Mesh]
View complete results in PubMed (results may change over time).
Edit saved search settings, or unsubscribe from these e-mail updates.
Items 1 - 7 of 7
PubMed Results
1. Colorectal Dis. 2014 Jan;16(1):15-6. doi: 10.1111/codi.12494. Commentary on Sajid et al.
Bach SP.Author information:
University of Birmingham, Birmingham, UK; Queen Elizabeth Hospital Birmingham, Birmingham, UK. s.p....@bham.ac.uk.PMID: 24330433 [PubMed - indexed for MEDLINE] Related citations 
2. Colorectal Dis. 2014 Jan;16(1):2-14. doi: 10.1111/codi.12474. Systematic review and meta-analysis of published trials comparing the effectiveness of transanal endoscopic microsurgery and radical resection in the management of early rectal cancer.
Sajid MS1, Farag S, Leung P, Sains P, Miles WF, Baig MK.Author information:
1Department of General and Laparoscopic Colorectal Surgery, Western Sussex Hospitals NHS Trust, Worthing Hospital, Worthing, UK.Comment in
- Commentary on Sajid et al. [Colorectal Dis. 2014]
Abstract
AIM:
A systematic analysis was conducted of trials comparing the effectiveness of transanal endoscopic microsurgery (TEMS) with radical resection (RR) for T1 and T2 rectal cancer.
METHOD:
An electronic search was carried out of trials reporting the effectiveness of TEMS and RR in the treatment of T1 and T2 rectal cancers.
RESULTS:
Ten trials including 942 patients were retrieved. There was a trend toward a higher risk of local recurrence (odds ratio 2.78; 95% confidence interval 1.42, 5.44; z = 2.97; P < 0.003) and overall recurrence (P < 0.01) following TEMS compared with RR. The risk of distant recurrence, overall survival (odds ratio 0.90; 95% confidence interval 0.49, 1.66; z = 0.33; P = 0.74) and mortality was similar. TEMS was associated with a shorter operation time and hospital stay and a reduced risk of postoperative complications (P < 0.0001). The included studies, however, were significantly diverse in stage and grade of rectal cancer and the use of neoadjuvant chemoradiotherapy.
CONCLUSION:
Transanal endoscopic microsurgery appears to have clinically measurable advantages in patients with early rectal cancer. The studies included in this review do not allow firm conclusions as to whether TEMS is superior to RR in the management of early rectal cancer. Larger, better designed and executed prospective studies are needed to answer this question.
Colorectal Disease © 2013 The Association of Coloproctology of Great Britain and Ireland.
PMID: 24330432 [PubMed - indexed for MEDLINE] Related citations
3. Minim Invasive Ther Allied Technol. 2014 Jan;23(1):28-31. doi: 10.3109/13645706.2013.872663. Epub 2013 Dec 13. Transanal endoscopic microsurgery: also for the treatment of retrorectal tumors.
Duek SD1, Gilshtein H, Khoury W.Author information:
1Colorectal Surgery Unit, Department of General Surgery, Rambam Health Care Campus, Bruce Rappaport Medical School, Technion , Haifa , Israel.Abstract
Retrorectal tumors are an uncommon pathological entity. Their clinical importance arises from their occasional malignant nature or malignant transformation. The treatment of choice for most presacral tumors is surgical excision. The approach depends upon the upper limit of the lesion and the presumptive pathology. We reviewed the main features of these tumors with emphasis on transanal endoscopic microsurgery (TEM) as a viable surgical approach for the treatment of the lesions, undertaken in our institution. We present our small case series, consisting of six patients with retrorectal lesions who underwent local excision via TEM. Early and late postoperative outcomes are presented. TEM for retrorectal lesions appears to be a feasible and safe approach. A remarkably low morbidity favors TEM in selected patients.
PMID: 24329013 [PubMed - indexed for MEDLINE] Related citations 
4. Minim Invasive Ther Allied Technol. 2014 Jan;23(1):1-4. doi: 10.3109/13645706.2013.871294. Epub 2013 Dec 12. The outburst age: how TEM ignited the MIS revolution.
Lirici MM1, Kanehira E, Melzer A, Schurr MO.Author information:
1San Giovanni Hospital, Surgery , Rome , Italy.PMID: 24328982 [PubMed - indexed for MEDLINE] Related citations
5. Minim Invasive Ther Allied Technol. 2014 Jan;23(1):5-9. doi: 10.3109/13645706.2013.868814. Epub 2013 Dec 12. A single surgeon's experience with transanal endoscopic microsurgery over 20 years with 153 early cancer cases.
Kanehira E1, Tanida T, Kamei A, Nakagi M, Hideshima A.Author information:
1Department of Surgery, Medical Topia Soka , Soka City, Saitama , Japan.Abstract
BACKGROUND:
The first author performed transanal endoscopic surgery (TEM) in 302 patients in Japan for the last 20 years, 153 of which were early rectal cancer cases. The short- and long-term outcomes of the early rectal cancer cases are herein reported.
MATERIAL AND METHODS:
The original technique of TEM developed by Gerhard Buess was performed in all cases. The hospital records were reviewed to assess the clinical outcomes. A questionnaire was sent to the patients to analyze the long-term outcomes.
RESULTS:
One-hundred and fifty-three early cancer cases included 115 T0 and 38 T1 lesions. Full-thickness resection was performed in 36 patients, while 117 underwent submucosal dissection. Conversion to laparoscopic low anterior resection occurred in one case. Mortality was nil. Major operative complication was noted in only one patient, who developed stenosis. Seven patients underwent immediate salvage surgery. Six patients died of recurrence of rectal cancer. Disease-free survival rate at year 5 was 93.7%.
CONCLUSIONS:
Our study, one of the largest series in the world, confirms that TEM is a preferable option in the surgical treatment of T0 and T1a rectal carcinoma. As long as early cancer cases are treated, submucosal resection seems to be sufficient. When risk of recurrence is found by pathological examination, immediate salvage operation is mandatory to improve the prognosis.
PMID: 24328981 [PubMed - indexed for MEDLINE] Related citations
6. Minim Invasive Ther Allied Technol. 2014 Jan;23(1):21-7. doi: 10.3109/13645706.2013.833117. Epub 2013 Sep 1. Which treatment for large rectal adenoma? Preoperative assessment and therapeutic strategy.
Arezzo A1, Arolfo S, Cravero F, Migliore M, Allaix ME, Morino M.Author information:
1Department of Surgical Sciences, University of Torino , Torino , Italy.Abstract
In the present review the authors discuss the standard ways of preoperative work-up for a suspected large rectal non-invasive lesion, comparing East and West different attitudes both in staging and treatment. Looking at the literature and analyzing recent personal data, neither pit-pattern classification, nor EUS, nor biopsy histology, nor lifting sign verification, nor digital examination allow a specificity of more than three fourth of such cases. The authors disquisition about which optimal treatment excludes a role for EMR for the impossibility to obtain a single en-bloc specimen, minimum requirement for a correct lateral and vertical margin assessment. For the same reason ESD should be preferred, although a recent meta-analysis of the literature defined that one fourth of patients undergoing ESD for a preoperatively assessed non-invasive large rectal lesion fail to receive an R0 en-bloc resection. This forces about 10% of patients treated by flexible endoscopy to undergo abdominal surgery, which is about fourfold higher than TEM. While awaiting further implementation of modern technologies both to improve staging and to reduce invasiveness, a full-thickness excision of the rectal wall by TEM still represents the standard treatment even for suspected benign diseases.
PMID: 23992387 [PubMed - indexed for MEDLINE] Related citations
7. Minim Invasive Ther Allied Technol. 2014 Jan;23(1):17-20. doi: 10.3109/13645706.2013.789061. Epub 2013 Apr 17. Transrectal sentinel lymph node biopsy for early rectal cancer during transanal endoscopic microsurgery.
Arezzo A1, Arolfo S, Mistrangelo M, Mussa B, Cassoni P, Morino M.Author information:
1Department of Surgical Sciences, University of Torino , Torino , Italy.Abstract
BACKGROUND:
Local excision of invasive cancer by transanal endoscopic microsurgery (TEM) entails the risk of lymphnode metastases that obliges to radical surgery. A determination of metastatic lymph-nodes would avoid major surgery in the vast majority of cases. We applied the concept of sentinel lymphnode (SLN) biopsy to suspected invasive rectal cancers treated by TEM.
METHODS:
Indocyanine green (ICG) is injected in the submucosa underneath the lesion. The tumor is dissected full-thickness until the perirectal fat. A near infra-red (NIR) optic provides a map of mesorectal lymphatics, on which guide the perirectal fat is dissected and lymph-nodes are excised.
RESULTS:
The technique was tested in three patients. In all cases the pathologist confirmed presence of lymphnodes in the excised tissue, no case showed metastasis. In all cases final pathology of the rectal neoplasm did not indicate radical surgery.
CONCLUSION:
In suspected invasive cancers, SLN mapping could be a useful technique to identify the first lymph node receiving drainage from the tumour, whose accurate pathological examination could predict the status of the remaining nodes and indicate further radical surgery. An ongoing study on a prospective case series will assess sensitivity and negative predictive value of SLN biopsy.
PMID: 23590395 [PubMed - indexed for MEDLINE] Related citations