my use of VGL

[SoJa]

Hello ☺
I use VGLII as part of my introduction courses in mendelian genetics
for 2nd year university students enrolled in Biology (Bordeaux,
France). After only one year trial, I found that having to design the
experimental crosses rather than just analyse results from a
conventional problem greatly improves hypothesis testing and
construction of scientific interpretations. It also enhances self-
confidence in all steps of genetic model building. VGLII therefore
offers an excellent compromise between traditional exercise books and
practical training on living organisms which are unfortunately not
affordable for that many students (200/year).
The lab training course is introduced by a 2-hours lecture supported
by a paper handout: in a first part, the objectives of the lab session
are presented as well as a description of VGLII commands and menus. In
a second part, students are shown a demonstration involving an easy
genetic determinism level (one gene on the X chromosome). During the
lab course, they have to deal with the segregation of 2-3 genes. They
are expected to demonstrate dominance/co or semi-dominance/recessivity
of the phenotypes, number of genes involved, whether genes are
autosomal or not and whether they are genetically linked or not, they
should chose adequate crosses (F1xF1, or backcrosses) and ultimately
calculate genetic distances. Their results must be comforted by
statistical analysis. TAs are requested all along for close guided
discussion. The lab class offers their first occasion to the students
to write a lab report in the format of a mini research article. This
is particularly relevant as they design the experiments by themselves
rather than being guided as in conventional lab courses and will
provide their own and unique interpretation.
All in all VGL makes genetics friendly and students are super positive
about the course!
I am happy to share my resources (lab handout and data on the
evaluation of this program) and learn more from your personal
experience of VGL.

Sophie

Prof. Sophie JAVERZAT

Université de Bordeaux 1
Responsable de la Licence Biologie
---------------------------------------------
INSERM U920
Mécanismes Moléculaires de l’Angiogenèse

Avenue des Facultés 33405 Talence
tel: 05 4000 8702 fax: 05 4000 8705
s.jav...@angio.u-bordeaux1.fr
http://www.u-bordeaux1.fr/U920/Site/javerzat.html