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Phoebe Hanna
Cellular Respiration Study Guide
1) Glycolysis (cytoplasm)
in – glucose
out – 2 pyruvate
-- provides enough energy for the immediate buildup of 2 ATP
--gain of 2 NADH
2) Preparatory Reaction (mitochondria)
in – 2 pyruvate
out – C2 acetyl group attached to CoA, 2 CO2
-- CO2 is given off
-- Reaction occurs twice per glucose molecule
3) Citric Acid/Krebs Cycle (matrix of mitochondria)
in – acetyl-CoA molecules
out – 4 CO2 per glucose molecule
-- 2 ATP per glucose molecule
4) Electron Transport Chain (cristae of the mitochondria)
in – 2 electrons for each NADH and FADH2 (which bring the electrons to the electron transport chain)
out – 3 ATP for each pair of electrons that entered by way of NADH, 2 ATP for each pair of electrons that entered by way of FADH2, O2 combines with H+ ions, forming H2O
-- 32 or 34 ATP
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Total number of ATP = 36 or 38
Organization of Cristae
-- within the cristae: electron transport chain
--The H+ flows through an ATP synthase complex from the intermembrane space into the matrix.
-- Chemiosmosis – how mitochondria produce ATP
-- ATP production is dependent upon the unequal distribution of H+ established by the pumping of H+ into the intermembrane space.
Fermentation
Def.: the metabolical recycling of NADH and producing NAD+ to continue glycolysis in the absence of oxygen
-- lactic acid (humans)
-- alcohol (e.g. yeast)
-- used, for example, during oxygen debt
-- produces 2 ATP (net)
Metabolism
-- all reactions in cellular respiration are a part of metabolism
-- substrates can be used for catabolism and anabolism
--catabolism: breaking down molecules
e.g. proteins à amino acids
carbohydrates à glucose
fats à glycerol, fatty acids
--deamination: process that removes amino groups from amino acids (amino groups can’t be respired)
--anabolism: the building up of molecules